Hemorragia intraventricular em bebês
Revisado por Dra. Anjum Gandhi, FRCPCHÚltima atualização por Dra. Mary Harding, MRCGPÚltima atualização 31 de maio de 2018
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Nesta série:Bebês prematurosAlimentação de bebês prematurosEnterocolite necrosanteRetinopatia da prematuridade
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Uma hemorragia intraventricular é um sangramento no cérebro. Bebês prematuros estão particularmente em risco dessa condição.
Em resumo
An intraventricular haemorrhage (IVH) is bleeding into fluid-filled spaces in the brain called ventricles.
This type of bleed is more common in premature babies due to fragile blood vessels.
Signs can include floppiness, less alertness, fits, or swelling of the soft spots on the head.
IVH is usually diagnosed using an ultrasound scan on the baby's head.
There is no specific treatment, but the bleed is monitored as it usually reduces over time.
More severe bleeds (Grade 3 or 4) can lead to long-term issues like cerebral palsy.
Steroid medicines given to women in premature labour may help prevent some cases of IVH.
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O que é uma hemorragia intraventricular?
A haemorrhage means a bleed - that is blood leaking out of blood vessels into the area surrounding the blood vessel. An intraventricular haemorrhage (IVH) is a bleed into the brain. Specifically, a bleed into fluid-filled spaces in the brain, called ventricles.
An IVH can occur at any age. It is a type of derrame, and may be due to various causes including pressão alta, a head injury, abnormally formed blood vessels, or brain tumours.
This leaflet is specifically about intraventricular haemorrhage in newborn babies.
There is a high risk of IVH in babies who were born very early (premature babies).
Why are premature babies at risk of intraventricular haemorrhage?
In premature babies, the brain is still developing. The new blood vessels near the ventricles of the brain are very fragile. They can tear very easily, allowing blood to leak out and into the ventricles. Other medical conditions and fluctuations in the blood flow to the brain can make bleeding more likely.
Which babies are most at risk?
IVH is common in very premature babies and rare in babies who were not born early (babies born at term). The earlier the baby is born, the higher the risk of IVH. Also the lower the birth weight, the more the risk of IVH. About one in four babies weighing less than 1500 g develop IVH.
Other problems can put a premature baby more at risk of developing IVH. Other medical problems affecting the steadiness of the blood flow to the brain can increase the risk. For example, breathing problems, infections, low oxygen levels, heart conditions, etc. All these conditions in themselves are more likely in premature babies, which all adds to the reasons for IVH occurring in this group of babies.
Babies born at term have IVH much less commonly. It is usually due to complicated difficult deliveries, or due to underlying medical problems (such as abnormal bleeding tendencies).
What are the signs of intraventricular haemorrhage?
It depends on how big a bleed there has been. Small bleeds may not cause much harm and so there may not be any signs or symptoms. Larger bleeds will have more impact and may be more apparent. Bleeds are classified as Grades 1 to 4, depending on how much of the brain tissue is affected. Grade 1 is the mildest bleed, with Grade 4 being the most severe. These larger, more severe bleeds are more likely to cause long-term problems.
Possible signs of IVH include:
Being more floppy.
Being less alert.
Convulsões (ataques).
Swelling around the soft spots on the head (fontanelles).
Breathing less regularly.
Feeding less well.
Change in colour (becoming more pale or developing a bluish colour).
IVH in most cases occurs within the first few days after the baby is born.
Quais testes são necessários?
IVH is usually diagnosed with an ultrassonografia. This is the type of scan you have when you are pregnant, but in this case the probe is placed over the soft spots (fontanelles) of the baby's head. The scan is painless and uses sound waves. It can be performed in the neonatal intensive care unit.
What is the treatment for intraventricular haemorrhage?
There is no specific treatment. Your baby will be monitored to check the area of bleeding is gradually getting smaller. Think of it like a bruise inside the brain - much like any other bruise the body gradually re-absorbs the blood and the swelling gradually settles down. Your baby will be monitored for any damage which might have been caused by this pressure on the brain.
Some babies develop an accumulation of fluid in the brain, causing an increased pressure in the brain - this is called hydrocephalus. Premature babies are monitored so that this is picked up early if it is happening. This is done by measuring the size of their heads and by regular ultrasound scans. Sometimes this needs treating by placing a shunt (drain) in the brain to help clear the extra fluid. This involves an operation.
Qual é a perspectiva?
For lower-grade haemorrhages, the outlook (prognosis) is good. Long-term damage is unlikely. However, for babies who have had Grade 3 or Grade 4 IVH, there is a risk that damage to the brain will have longer-term consequences. More than half of these babies have brain problems as a result of the IVH. The type of problems the baby may have in future include:
Dificuldades de aprendizagem.
Delays in development.
Problems with eyesight or hearing.
Can intraventricular haemorrhage be prevented?
Lots of research has been done and is being done to look at ways of preventing IVH. The most important factor is babies being born prematurely, but of course it is often not possible to prevent this. Giving medicamentos esteroides para women in premature labour seems to help in preventing some cases of IVH.
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Perguntas frequentes
What is the primary cause of intraventricular haemorrhage (IVH) in premature babies?
In premature babies, the primary reason for IVH is that the blood vessels near the ventricles of the brain are still developing and are very fragile. These delicate vessels can easily tear, leading to blood leakage into the ventricles. Other factors like fluctuations in blood flow to the brain and other medical conditions can also increase the likelihood of bleeding.
How soon after birth does IVH typically occur in babies?
In most cases, intraventricular haemorrhage occurs within the first few days after a baby is born.
What specifically is a 'shunt' and why might a baby need one after an IVH?
A shunt is a drain that is surgically placed in the brain. Some babies develop hydrocephalus after an IVH, which is an accumulation of fluid in the brain causing increased pressure. A shunt helps to clear this extra fluid, relieving the pressure on the brain.
Are there any specific measures taken to monitor for brain damage caused by IVH's pressure?
Yes, babies are monitored for any damage that might be caused by pressure on the brain. This includes regularly measuring the size of their heads and performing regular ultrasound scans to check for the development of hydrocephalus, which is an accumulation of fluid. This monitoring helps ensure that any issues are detected early.
What is a fontanelle and why is it important for diagnosing IVH?
Fontanelles are the soft spots on a baby's head. They are important for diagnosing IVH because an ultrasound scan, which is the primary diagnostic tool, involves placing the probe over these soft spots to view the brain. Swelling around the fontanelles can also be a sign of IVH.
Leitura adicional e referências
- Bliss; instituição de caridade para bebês nascidos prematuros ou doentes
- Szpecht D, Frydryszak D, Miszczyk N, et al; The incidence of severe intraventricular hemorrhage based on retrospective analysis of 35939 full-term newborns-report of two cases and review of literature. Childs Nerv Syst. 2016 Dec;32(12):2447-2451. doi: 10.1007/s00381-016-3164-5. Epub 2016 Jul 8.
- Szpecht D, Nowak I, Kwiatkowska P, et al; Intraventricular hemorrhage in neonates born from 23 to 26 weeks of gestation: Retrospective analysis of risk factors. Adv Clin Exp Med. 2017 Jan-Feb;26(1):89-94.
- Ballabh P; Pathogenesis and prevention of intraventricular hemorrhage. Clin Perinatol. 2014 Mar;41(1):47-67. doi: 10.1016/j.clp.2013.09.007. Epub 2013 Dec 12.
Sobre o autorVer biografia completa

Dra. Mary Harding, MRCGP
Médico Generalista, Autor Médico
BA, MA, MB, BChir, MRCGP, DFFP
A Dra. Mary Harding se formou na faculdade de medicina da Universidade de Cambridge em 1989.
Sobre o revisorVer biografia completa

Dr Anjum Gandhi, FRCPCH
Consultor Pediatra
MBBS, MD, MRCP, FRCPCH
Dr. Anjum Gandhi tem mais de 25 anos de experiência clínica, de ensino e de pesquisa em pediatria e é Consultor Pediatra.
Histórico do artigo
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31 de maio de 2018 | Última versão

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