Dexamethasone

About dexamethasone

Dexamethasone belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Corticosteroids are produced naturally in your body. They help to keep you healthy. By boosting your body with extra corticosteroid, it can help treat conditions involving inflammation.

Oral steroids are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases (for example, Doença de Crohn, colite ulcerativa), autoimmune diseases (for example, lúpus eritematoso sistêmico (LES), sarcoidosis), joint and muscle diseases (for example, artrite reumatoide), and allergies. Dexamethasone is also used in the treatment of some cancers and in people receiving palliative care. In children, it is prescribed to treat a breathing condition called croup.

Dexamethasone is also used to diagnose Cushing's disease (an adrenal gland disorder), and is prescribed as a treatment for people who have a disorder called hiperplasia adrenal congênita (HAC).

Dexamethasone is also used to treat inflammation in the eyes. More information about this can be found in our leaflet Dexamethasone eye drops for inflammation.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking dexamethasone it is important that your doctor knows:

• Se você tem pressão alta (hipertensão).

• If you have had a heart attack, or if you have any other heart problems.

• Se você tiver algum problema com o funcionamento do seu fígado, ou se tiver algum problema com o funcionamento dos seus rins.

• If you (or a close family member) have either diabetes or an eye condition called glaucoma.

• If you have any of the following conditions: an underactive thyroid gland, 'thinning' of the bones (osteoporosis), epilepsy, a condition causing muscle weakness (called myasthenia gravis), a stomach ulcer, or a bowel disorder.

• If you have ever had a mental health problem.

• If you are pregnant or breastfeeding. (Oral steroids like dexamethasone can be taken while you are expecting or breastfeeding; however, it is important that your doctor knows about the baby.)

• If you have any kind of infection at the moment, or if you have ever had tuberculosis (TB).

• If you have ever had an unwanted blood clot in an artery or a vein.

• If you have recently had, or are about to have, any vaccinations.

• If you are taking or using any other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.

• Se você já teve uma reação alérgica a um medicamento, ou se já desenvolveu dor muscular após tomar um medicamento esteroide.

• Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about dexamethasone and will also provide you with a full list of side-effects which you could experience from taking it.

• Your doctor or pharmacist will tell you how much to take, and when to take your doses. Depending upon the reason why you are taking dexamethasone, you will be prescribed either a single dose, or a course of treatment. If you are prescribed a single dose, your doctor will tell you at what time to take the medicine. If you are prescribed a course of treatment, it is usual to take the doses once a day, straight after breakfast. However, if you are taking dexamethasone for CAH or as a test for Cushing's syndrome, you will be advised to take your doses at bedtime.

• Take dexamethasone with something to eat. Swallow the tablet with a drink of water.

• If you forget to take a dose at your usual time, take it as soon as you remember (with something to eat). If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

• Continue to take dexamethasone until your doctor tells you to stop. Once you have been taking dexamethasone for more than three weeks, stopping taking it suddenly can cause problems, so your doctor will want to reduce your dose gradually over a period of time if/when this becomes necessary.

• If your course of treatment is due to last more than three weeks, you will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking dexamethasone for, and who prescribed it for you. Please make sure that this information is kept up to date. If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking dexamethasone and show them your treatment card. This is because your dose may need adjusting.

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have tests from time to time to make sure you remain free from some of the unwanted side-effects of treatment.

• Dexamethasone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you deve consulte seu médico o mais rápido possível.

• Some vaccines are not suitable for you while you are being treated with dexamethasone. If you need any immunisations, make sure you mention that you are taking an oral steroid.

• If you buy any medicines, check with your pharmacist that they are suitable to take with dexamethasone.

Along with its useful effects, dexamethasone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking an oral steroid usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with dexamethasone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.

Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:

Importante: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking dexamethasone.

For more information about side-effects which are possible when dexamethasone is taken long-term, see the separate leaflet called Oral Steroids.

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