Comprimidos de Metilprednisolona
Medrone
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 21 Set 2022
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Methylprednisolone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Seu farmacêutico lhe dará um 'Cartão de Tratamento com Esteroides' azul. Carregue-o com você o tempo todo.
Take methylprednisolone tablets with food.
If you need any medical treatment, make sure the person treating you knows you are taking methylprednisolone. This is because your dose may need to be increased for a short while.
Em resumo
Methylprednisolone is a corticosteroid medicine used to treat many allergic and inflammatory conditions.
It works by interfering with chemicals in your body that cause inflammation.
Take your tablets once daily with food, usually at breakfast time.
Do not stop taking methylprednisolone suddenly; your doctor will need to reduce your dose gradually.
Carry a Steroid Treatment Card if your course of treatment lasts more than three weeks.
See your doctor straight away if you become ill or think you have been in contact with chickenpox, measles, or shingles.
About methylprednisolone
Tipo de medicamento | Um medicamento corticosteroide |
Usado para | Allergic and inflammatory conditions |
Também chamado de | Medrone®; Depo-Medrone®; Solu-Medrone® |
Disponível como | Comprimidos e injeção |
Methylprednisolone tablets belong to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Esteroides orais are used to treat a wide variety of conditions. Some examples include inflammatory bowel diseases (for example, Doença de Crohn, colite ulcerativa), autoimmune diseases (for example, lúpus eritematoso sistêmico (LES), sarcodose), joint and muscle diseases (for example, artrite reumatoide), and alergias. They are also used to treat some cancers.
Methylprednisolone works in part by interfering with the release of certain chemicals in your body which cause inflammation.
Methylprednisolone is also available in the form of an injection. Some types of injection are used when treatment is needed quickly, or a person is unable to swallow tablets. Other types of injection are given to relieve inflammation in a specific area, such as a painful or swollen joint. This leaflet gives advice for people taking methylprednisolone tablets.
Before taking methylprednisolone
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking methylprednisolone it is important that your doctor knows:
Se você tem pressão alta (hipertensão).
Se você teve um ataque cardíaco, ou se tem qualquer outro problema cardíaco.
Se você tiver algum problema com o funcionamento do seu fígado, ou se tiver algum problema com o funcionamento dos seus rins.
Se você (ou um parente próximo) tem diabetes ou uma condição ocular chamada glaucoma.
If you have any of the following conditions: an underactive thyroid, 'thinning' of the bones (osteoporosis), epilepsy, a condition causing muscle weakness (called myasthenia gravis), a stomach ulcer, or a bowel disorder.
Se você já teve um problema de saúde mental.
If you are pregnant or breastfeeding. (Oral steroids like methylprednisolone can be taken while you are expecting or breastfeeding; however, it is important that your doctor knows about the baby.)
Se você tem qualquer tipo de infecção no momento, ou se já teve tuberculose (TB).
Se você já teve um coágulo sanguíneo indesejado em uma artéria ou veia.
Se você recentemente tomou, ou está prestes a tomar, alguma vacina.
If you are taking other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Se você já teve uma reação alérgica a um medicamento, ou se já desenvolveu dor muscular após tomar um medicamento esteroide.
How to take methylprednisolone tablets
Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about methylprednisolone and will also provide you with a full list of side-effects which you could experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take for each dose. It is usual to take methylprednisolone once daily at breakfast-time. If you have been told otherwise, you must take the tablets exactly as you have been told by your doctor.
Take methylprednisolone with food. Swallow the tablet with a drink of water.
Se você esquecer de tomar uma dose no horário habitual, tome-a assim que se lembrar (com algo para comer). Se você não se lembrar até o dia seguinte, pule a dose esquecida. Não tome duas doses juntas para compensar uma dose esquecida.
Continue to take methylprednisolone until your doctor tells you to stop. Stopping taking the tablets suddenly can cause problems so your doctor will want you to reduce your dose gradually over a period of time if/when this becomes necessary.
Obtendo o máximo do seu tratamento
If your course of treatment is due to last more than three weeks, you will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking methylprednisolone for, and who prescribed it for you. Please make sure that this information is kept up to date. If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking methylprednisolone and show them your treatment card. This is because your dose may need adjusting.
Tente manter suas consultas regulares com seu médico. Isso é para que seu médico possa verificar seu progresso. Seu médico desejará que você faça exames de tempos em tempos para garantir que você permaneça livre de alguns dos efeitos colaterais indesejados do tratamento.
There are several strengths of methylprednisolone tablets available: 2 mg, 4 mg, 16 mg, and 100 mg. Each time you collect a new supply of tablets from your pharmacy, check to see if the tablets are the same as before. If they are different, speak with your pharmacist who will check it out for you.
Methylprednisolone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you deve see your doctor as soon as possible.
Some vaccines are not suitable for you while you are being treated with methylprednisolone. If you need any immunisations, make sure you mention that you are taking an oral steroid.
It is best not to drink grapefruit juice while you are on methylprednisolone. This is because a chemical in grapefruit juice is thought to increase the amount of methylprednisolone in your bloodstream, and could make side-effects more likely.
If you buy any medicines, check with your pharmacist that they are suitable to take with methylprednisolone.
Can methylprednisolone cause problems?
Along with its useful effects, methylprednisolone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking an oral steroid usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with methylprednisolone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below.
Embora nem todos experimentem efeitos colaterais, e alguns melhorem à medida que seu corpo se ajusta ao novo medicamento, fale com seu médico ou farmacêutico se ficar preocupado com qualquer um dos seguintes:
Comum methylprednisolone side-effects | O que posso fazer se passar por isso? |
Dor de barriga (abdominal), indigestão, sensação de enjoo (náusea) | Mantenha-se em alimentos simples. Se você estiver doente (vomitar) e houver sangue presente, deve falar com seu médico imediatamente |
Fraqueza muscular ou sensação de cansaço | Não dirija e não use ferramentas ou máquinas enquanto estiver afetado |
Mudanças de humor ou comportamento, especialmente no início do tratamento | If you become confused, irritable or start having worrying thoughts about harming yourself, speak with your doctor straightaway |
Dificuldades para dormir, dor de cabeça, aumento de peso e períodos irregulares em mulheres | Se algum desses se tornar problemático, fale com seu médico |
Risco aumentado de contrair uma infecção | Se você ficar doente, marque uma consulta para ver seu médico imediatamente |
Long-term treatment with methylprednisolone may cause other unwanted effects | Se você tiver algum sintoma que esteja causando preocupação, deve marcar uma consulta com seu médico para obter aconselhamento |
Importante: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking methylprednisolone.
For more information about side-effects which are possible when methylprednisolone is taken long-term, see the separate leaflet called Esteroides Orais.
How to store methylprednisolone tablets
Mantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Informações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

Inseguro sobre misturar medicamentos?
Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.
Perguntas frequentes
Can I take all my methylprednisolone tablets at once in the morning?
Yes, it is common to take methylprednisolone once daily at breakfast-time. However, you should always follow the specific instructions given by your doctor regarding how many tablets to take for each dose and when to take them.
Why would my doctor prescribe methylprednisolone given the potential side-effects?
Methylprednisolone is prescribed to treat a wide range of conditions, including various allergic reactions and inflammatory diseases. Your doctor will have discussed the potential side-effects with you, and generally, the benefits of taking an oral steroid like methylprednisolone are considered to outweigh the risks from its side-effects.
I'm told to take this with food. Does it matter what kind of food?
Yes, it is important to take methylprednisolone with food. You should generally stick to simple foods if you experience tummy pain, indigestion, or nausea. Additionally, you should avoid drinking grapefruit juice as it is thought to increase the amount of methylprednisolone in your bloodstream, potentially making side-effects more likely.
I'm worried about getting infections while taking this medicine. What should I do?
Methylprednisolone can suppress your immune system, increasing your risk of infection. If you become ill, you should make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles, or chickenpox (or suspects they might have them), you must see your doctor as soon as possible.
What should I do if I think I've taken too much methylprednisolone?
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Leitura adicional e referências
- Manufacturer's PIL, Medrone® Tablets 2 mg, 4 mg; Pfizer Limited, The electronic Medicines Compendium. Dated November 2018.
- Manufacturer's PIL, Medrone® 100 mg Tablets; Pfizer Limited, O Compêndio Eletrônico de Medicamentos. Data de outubro de 2020.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
Sobre o revisor

Sid Dajani
Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.

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