Ibuprofeno para dor e inflamação
Brufen, Calprofen, Nurofen
Revisado por Dr Colin Tidy, MRCGPÚltima atualização por Michael Stewart, MRPharmSLast updated 27 Fev 2023
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Ibuprofen is a painkiller that eases pain and reduces inflammation. It should be taken with a meal or a snack.
The most common side effects are stomach ache, indigestion, feeling sick (nausea), and being sick (vomiting).
Ibuprofen is not recommended for children who have chickenpox. Use paracetamol instead.
Speak with a doctor before taking ibuprofen if you have ever had a bad reaction to any other anti-inflammatory painkiller.
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About ibuprofen
Tipo de medicamento | Um medicamento anti-inflamatório não esteroidal (AINE) |
Usado para | Relief of pain, inflammation, or fever |
Também chamado (Reino Unido) | Anadin®, Brufen®; Calprofen®; Cuprofen®; Fenpaed®; Feminax®; Flarin®; Ibucalm®; Noubid®; Nurofen® |
Também chamado (EUA) | Advil®; Alivio®; Aprofen®; Cedaprin®; CounterAct® IB; Dolex®; Dragon Tabs®; Flex-Prin®; Ibutab®; Motrin® IB; Probufen®; Profen® IB; Proprinal® |
Disponível como | Tablets, capsules, effervescent granules, oral liquid medicine, modified-release tablets, orodispersible (melt in the mouth) tablets, chewable capsules |
What is ibuprofen used for?
Voltar ao conteúdoIbuprofen is a type of anti-inflammatory painkiller (also called non-steroidal anti-inflammatory drugs (NSAIDs), or 'anti-inflammatories') that is used to treat pain and reduce inflammation (swelling).
Conditions that it is commonly used to treat include:
Dental pain.
Pain after surgical operations.
Ibuprofen can also be used to relieve cold and 'flu-like' symptoms including febre (temperatura alta). It can be taken by adults and by children over the age of 3 months.
Ibuprofen is available on prescription, and you can also buy a number of preparations which contain ibuprofen without a prescription at pharmacies and other retail outlets.
It is also available as a gel which can be applied directly to your skin to help relieve muscle and joint pain.
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How does ibuprofen work?
Voltar ao conteúdoIbuprofen works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes.
These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation.
By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
Side effects of ibuprofen
Voltar ao conteúdoCommon side effects of ibuprofen are:
Indigestão.
Queimação no estômago.
Dor de estômago.
Sentindo-se mal.
Vômito.
Diarreia.
You will find a full list of the side effects associated with ibuprofen from the manufacturer's printed information leaflet supplied with the medicine.
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How to manage ibuprofen side effects
Voltar ao conteúdoOs efeitos indesejados muitas vezes melhoram à medida que seu corpo se ajusta ao novo medicamento, mas fale com seu médico ou farmacêutico se algum dos seguintes persistir ou se tornar problemático.
Common ibuprofen side effects | O que posso fazer se passar por isso? |
Indigestion, heartburn, stomach pain | Remember to take your doses with food, or with a glass of milk. If the discomfort continues, speak with your doctor |
Feeling sick or being sick, diarrhoea | Stick to simple meals. Drink plenty of liquid to replace any lost fluids |
Importante: if you experience any of the following less frequent but possibly serious symptoms, stop taking ibuprofen and contact your doctor for advice straightaway:
Se você tiver alguma dificuldade respiratória, como chiado ou falta de ar.
If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.
If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.
Ibuprofen may increase the risk of developing serious skin infections when used in children with chickenpox. Therefore, paracetamol is usually recommended in chickenpox and ibuprofen should not be used.
Ibuprofen does not affect your ability to drive or to use machinery.
Se você sentir quaisquer outros sintomas que acha que podem ser devido ao medicamento, fale com seu médico ou farmacêutico para mais conselhos.
Who should not take ibuprofen?
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions. Before taking ibuprofen it is important that your doctor knows:
If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Doença de Crohn ou colite ulcerativa.
If you have asma or any other allergic disorder.
Se você está grávida, tentando ter um bebê ou amamentando.
Se você tiver algum problema com o funcionamento do seu fígado, ou se tiver algum problema com o funcionamento dos seus rins.
Se você tem uma condição cardíaca ou um problema com seus vasos sanguíneos ou circulação.
If you have pressão alta.
Se você tiver algum problema de coagulação sanguínea.
Se você tem níveis elevados de açúcar no sangue ou colesterol.
Se você tem um distúrbio do tecido conjuntivo, como lúpus eritematoso sistêmico. Esta é uma condição inflamatória que também é chamada de lúpus ou LES.
Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
If you have ever had an allergic reaction to any other NSAID (such as aspirina, naproxeno, diclofenaco, e indometacina), ou a qualquer outro medicamento.
How to take ibuprofen
Voltar ao conteúdoBefore you take ibuprofen, read the leaflet in the pack. It explains how the medicine works and lists possible side effects.
For adults and children 12 and older, the usual dose is 200-400 mg three or four times a day if needed. If your tablets are the slow-release kind, the dose is different - they’re usually taken once or twice a day.
Different brands may have different strengths, so always check the label to make sure you’re taking the right amount
If you’re giving liquid ibuprofen to a child, the dose depends on their age. Read the bottle label carefully so you give the correct amount. The doses below are a general guide for a 100 mg/5 ml ibuprofen suspension.
3-5 months: 50 mg (2.5 ml) three times daily.
6-11 months: 50 mg (2.5 ml) three or four times daily.
1-3 years: 100 mg (5 ml) three times daily.
4-6 years: 150 mg (7.5 ml) three times daily.
7-9 years: 200 mg (10 ml) three times daily.
10-11 years: 300 mg (15 ml) three times daily.
Ibuprofen is best taken with food. This will help to protect your stomach from side effects such as indigestão.
If you have been prescribed a modified-release form of ibuprofen (Brufen Retard® brand), swallow the tablet or capsule whole with a glass of water. Do not crush or break the tablets.
If you have been prescribed a sachet containing ibuprofen granules (Brufen® Effervescent Granules), mix the contents of the sachet into a glass of water to make a fizzy drink. Drink it straightaway after mixing it.
If you forget a dose, take it when you remember - unless it’s almost time for your next one. If it is, just skip the missed dose and take the next one as normal. Não tome duas doses de uma vez.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoYour doctor will give you the lowest dose of ibuprofen for the shortest time to help avoid side effects. If you need it long-term, they might also give you another medicine to protect your stomach.
If you bought ibuprofen yourself, only use it for a short time and stop once the pain or fever goes away.
Keep your regular check-ups with your doctor, especially if you're taking ibuprofen for a long-term problem.
If you have asthma, ibuprofen can sometimes make symptoms like wheezing or breathlessness worse. If that happens, stop taking it and see your doctor.
Some anti-inflammatory medicines, including ibuprofen, may slightly increase the risk of heart and blood vessel problems if used long-term. If you’re worried, talk to a healthcare professional. Always stick to the recommended dose.
If you buy other medicines, check with a pharmacist that they’re safe to take with ibuprofen. Don’t take ibuprofen along with any other anti-inflammatory painkillers - some cold and flu medicines contain them.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando.
How to store ibuprofen
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.
Perguntas frequentes
Voltar ao conteúdoHow long does it take for ibuprofen to work?
Ibuprofen usually starts working within 20 to 30 minutes, with its full pain-relieving and anti-inflammatory effects typically felt after about 1 to 2 hours. How quickly it works can depend on your metabolism and the type of ibuprofen.
Can you take ibuprofen while pregnant?
You should avoid taking ibuprofen while pregnant, especially after 20 weeks, as it may affect the baby’s development and increase the risk of complications in later pregnancy.
Can you drink alcohol with ibuprofen?
It’s generally best to avoid alcohol while taking ibuprofen as it can increase the risk of stomach irritation, bleeding, and other side effects. However, drinking a small amount of alcohol is usually fine.
Can you take ibuprofen and paracetamol together?
Yes, ibuprofen and paracetamol can be taken together for short-term pain relief as they work differently in the body. They can also be taken alternately to maintain consistent relief.
Can you take ibuprofen with co-codamol?
Yes, you can take ibuprofen with co-codamol as they work differently to relieve pain. They can provide stronger pain control when used together. Always follow dosing instructions carefully.
How long does ibuprofen last?
The effects of ibuprofen typically last 4 to 6 hours, depending on the dose and formulation. Extended-release versions may last longer.

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Leitura adicional e referências
- Manufacturer's PIL, Ibuprofen 200 mg and 400 mg film-coated tablets (PL 16363/0523); Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated June 2020.
- Manufacturer's PIL, Ibuprofen 100 mg/5 ml Oral Suspension; Pinewood Healthcare Ltd, The electronic Medicines Compendium. Dated February 2023.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 8 de agosto de 2027
27 Fev 2023 | Última versão

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