Folic acid
folate - FolicA, FoliSol, Lexpec
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 17 Abr 2023
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As well as taking folic acid, try to eat a healthy diet containing lightly cooked green leafy vegetables.
Folic acid rarely causes side-effects.
At a glance
Folic acid is a vitamin (B9) important for growth and general health, also called folate.
It is used to treat folic acid deficiency and a type of anaemia.
Pregnant women should take folic acid to reduce the risk of birth defects like spina bifida.
Begin taking folic acid before pregnancy and continue for at least the first 12 weeks.
Folic acid is also used with methotrexate in some conditions to reduce side-effects.
You can buy 400 microgram tablets, but your doctor will prescribe 5 mg tablets.
Folic acid supplements are unlikely to cause side-effects.
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About folic acid
Tipo de medicamento | Vitamin B9 |
Usado para | Folic acid deficiency in adults and children; folic acid supplementation before/during pregnancy |
Também chamado de | Folate; FolicA®; FoliSol®; Lexpec® |
Disponível como | Tablets and oral liquid |
Folic acid in anaemia
Vitamins are substances required by our bodies in small amounts for growth and general health. Our bodies do not store very much folic acid so we need to have a regular fresh supply. We can usually get the amounts we need from the food that we eat. Many foods contain folic acid, including spinach, sprouts, broccoli, green beans, peas, chickpeas, brown rice, kidney, liver and potatoes. Some people, for various reasons, may not receive enough from their diet alone. Folic acid is important for the production of red blood cells. A lack of it can lead to anaemia, which can cause tiredness and sometimes other symptoms. Folic acid deficiency is treated easily by taking a course of folic acid tablets for a few months.
Folic acid in pregnancy
Pregnant women in particular need a good supply of folic acid because it is used by the developing baby. It has been shown that taking folic acid supplements decreases the chance of spina bifida and other neural tube defects in the baby. The very early stages of pregnancy are crucial in the need for folic acid and this is why folic acid supplements are recommended for women planning a pregnancy.
Extra folic acid is advised for at least the first 12 weeks of gravidez for all women - even if you are healthy and have a good diet. For most women, a supplement of 400 micrograms of folic acid a day from before conception until the twelfth week of pregnancy is recommended. It is best to start taking the extra folic acid before becoming pregnant. If the pregnancy is unplanned then start taking folic acid as soon as you know you are pregnant. You can buy tablets of folic acid at most health food shops or pharmacies.
If you have had a previous pregnancy affected by a neural tube defect or if there is a family history of such, a supplement of 5 mg (milligrams) of folic acid each day until the twelfth week is recommended. A supplement of 5 mg daily in pregnancy is also recommended with some medical conditions such as coeliac disease, diabetes, and sickle cell anaemia, and if you are taking medicines to treat epilepsy. This strength of folic acid tablet is not available to buy. Your doctor will prescribe the tablets for you.
Folic acid in other conditions
Folic acid is also used alongside metotrexato treatment in people with severe Doença de Crohn, psoríase, e artrite. When it is used in these medical conditions, folic acid is taken on a different day of the week to methotrexate. It is taken to reduce the side-effects which can be caused by methotrexate.
How to take folic acid
Voltar ao conteúdoIf you have bought folic acid tablets because you are planning to have a baby, read the manufacturer's printed information on the pack (or from inside it) before you start taking the tablets. Make sure you are clear about what dose to take - the recommended dose is 400 micrograms once daily. The 5 mg tablet has more than ten times as much folic acid as this. If you have any questions, ask a pharmacist to advise you.
If you have been prescribed 5 mg folic acid tablets by a doctor, take them exactly as you are told to. Depending upon the reason for which you are taking folic acid, you may be asked to take one tablet every day, or one tablet only on certain days of the week. Try to take your doses at the same time of day each day that you take them, as this will help you to remember to take the tablets regularly. There will be more information about folic acid on the manufacturer's printed information leaflet from inside your pack.
It is not important whether you take folic acid before or after meals.
If you forget to take a tablet, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.
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Obtendo o máximo do seu tratamento
Voltar ao conteúdoIn addition to taking folic acid, try also to eat a healthy diet including foods rich in folic acid, such as spinach, sprouts, broccoli, green beans and potatoes. Lightly cook the vegetables, as the cooking process reduces the amount of folic acid they contain. Some bread and breakfast cereals are fortified with folic acid also.
Can folic acid cause problems?
Voltar ao conteúdoFolic acid supplements are unlikely to cause any side-effects. The 5 mg tablets may, on rare occasions, cause mild upset stomach (loss of appetite, nausea, and a bloated feeling). If you experience any symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for advice.
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How to store folic acid
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Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

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Perguntas frequentes
What foods can help me get enough folic acid naturally?
Many foods contain folic acid, including spinach, sprouts, broccoli, green beans, peas, chickpeas, brown rice, kidney, liver and potatoes. Some bread and breakfast cereals are also fortified with folic acid. It's best to lightly cook vegetables such as spinach and broccoli, as extensive cooking can reduce their folic acid content.
If I am pregnant, when should I start taking folic acid?
It is best to start taking extra folic acid before becoming pregnant. If your pregnancy is unplanned, you should start taking folic acid as soon as you find out you are pregnant. Supplementation is recommended from before conception until the twelfth week of pregnancy.
What is the recommended dose of folic acid for most pregnant women?
For most women, a daily supplement of 400 micrograms of folic acid is recommended from before conception until the twelfth week of pregnancy. You can buy this strength of folic acid at most health food shops or pharmacies.
Are there any specific medical conditions or circumstances where a higher dose of folic acid is recommended during pregnancy?
Yes, a higher dose of 5 mg of folic acid each day until the twelfth week of pregnancy is recommended if you have had a previous pregnancy affected by a neural tube defect, or if there is a family history of such. This higher dose is also advised for some medical conditions like coeliac disease, diabetes, and sickle cell anaemia, or if you are taking medicines for epilepsy. This 5 mg strength requires a prescription from your doctor.
If I miss a dose of my folic acid tablets, what should I do?
If you forget to take a tablet, take it as soon as you remember. However, if you don't remember until the following day, you should skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.
Can folic acid be taken at any time of day, with or without food?
Yes, it is not important whether you take folic acid before or after meals. It's suggested to try and take your doses at the same time each day you take them to help you remember to take them regularly.
Are there any common side effects from taking folic acid supplements?
Folic acid supplements are generally unlikely to cause any side-effects. On rare occasions, the higher strength 5 mg tablets may cause mild upset stomach, which can include loss of appetite, nausea, and a bloated feeling.
Leitura adicional e referências
- Manufacturer's PIL, Folic Acid Tablets 5 mg; Wockhardt UK Ltd, electronic Medicines Compendium. Dated May 2018.
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About the authorView full bio

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista: 15 Out 2027
17 Abr 2023 | Última versão

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