Pular para o conteúdo principal

Dutasterida para aumento da glândula prostática

Avodart

Dutasteride is for men only. It must not be taken by women, children or adolescents.

Take one capsule each day.

Your symptoms may start to improve within a few weeks, although it can take up to six months for you to notice the full benefit.

Em resumo

  • Dutasteride is a medicine for men with an enlarged prostate gland, also called benign prostatic hyperplasia (BPH).

  • It works by shrinking the prostate, which helps to ease problems with passing urine.

  • Take one capsule every day at the same time, swallowing it whole without chewing.

  • It can take up to six months to feel the full benefit of this medicine.

  • Dutasteride can harm an unborn baby, so handle with care and use contraception if your partner could become pregnant.

  • Tell your doctor if you develop breast pain, lumps, or nipple discharge, as these can be rare side-effects.

About dutasteride

Tipo de medicamento

5-alpha reductase inhibitor

Usado para

Enlargement of the prostate gland in men

Também chamado de

Avodart®;
Combination brands: Combodart®; Dutrozen® (dutasteride with tamsulosina)

Disponível como

Cápsulas

The prostate gland commonly becomes larger in older men. O aumento da glândula prostática também é chamado de hiperplasia prostática benigna (HPB). The prostate is situated close to the bladder, so its enlargement can cause problems with passing urine. Common symptoms that are experienced are having to wait before your urine starts to flow, taking longer at the toilet, dribbling urine, and a feeling that your bladder is not quite empty.

Dutasteride works by blocking the conversion of the hormone testosterone to the more potent hormone dihydrotestosterone. It does this by blocking an enzyme called 5-alpha reductase. Dihydrotestosterone is partly responsible for making the prostate enlarge. Therefore, a reduced amount of dihydrotestosterone in the prostate causes it to shrink. This helps you to pass urine more easily.

Sometimes, more than one type of medicine is needed to control the symptoms of prostate enlargement. Dutasteride is available in combination with another medicine for prostate enlargement, called tamsulosina. The combination brand is called Combodart® and it may give quicker and better relief of symptoms than either medicine alone.

Before taking dutasteride

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dutasteride it is important that your doctor knows:

  • Se você já teve uma reação alérgica a um medicamento.

  • Se você tiver algum problema com o funcionamento do seu fígado.

  • Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

How to take dutasteride

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dutasteride and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take dutasteride exactly as your doctor tells you to. Take one capsule each day. Swallow the capsule whole - do not chew or open the capsule as this could irritate your mouth.

  • You can take the capsule either before or after a meal, but try to take the capsule at the same time of day each day. This will help you to remember to take your doses regularly.

  • If you forget to take a dose on time, take it when you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Obtendo o máximo do seu tratamento

  • Your symptoms may start to improve within a few weeks although it can take up to six months for you to notice the full benefit. This is because it takes time for the prostate gland to gradually shrink. Because of this, it is important that you continue to take the capsules regularly, even if you don't feel a benefit straightaway.

  • Remember to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

  • Consider reducing or stopping the amount of caffeine you drink (commonly found in tea, coffee and cola) and alcohol. These can make your symptoms worse, so drinking less of these things may benefit you.

  • If you are a smoker, stopping smoking may significantly improve your symptoms. This is because nicotine irritates the bladder. Ask your doctor for advice on quitting.

  • Dutasteride may cause harm to an unborn baby. Because of this, women who are pregnant should not handle these capsules if they are damaged or leaking. Also, small amounts of dutasteride will be in your semen while you are taking this medicine, and it is therefore recommended that you use a barrier method of contraception (such as a condom) if your partner could become pregnant. If you need further advice about this, speak with your pharmacist or doctor.

  • If you are having an operation or any medical treatment, tell the person carrying out the treatment that you are taking dutasteride. This is because dutasteride can interfere with a blood test used to detect prostate cancer, so you must tell your doctor about taking dutasteride if you need this test.

Can dutasteride cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with dutasteride. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common dutasteride side-effects (these affect fewer than 1 in 10 men)

O que posso fazer se passar por isso?

Reduced desire to have sex, inability to get an erection, breast tenderness

Se algum desses se tornar problemático, fale com seu médico

Dizziness when taken with tamsulosin

Não dirija e não use ferramentas ou máquinas enquanto estiver afetado

Importante: if you develop any pain or lumps in your breast area, or any discharge from your nipples, you should tell your doctor. This is because there have been a few rare reports of breast cancer in men taking 5-alpha reductase inhibitors like finasteride and dutasteride.

Se você sentir quaisquer outros sintomas que acha que podem ser devido ao medicamento, fale com seu médico ou farmacêutico para mais conselhos.

How to store dutasteride

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

If you buy any medicines, always check with a pharmacist that they are safe to take alongside your prescribed medicines.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

verificador de sintomas

Inseguro sobre misturar medicamentos?

Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.

Perguntas frequentes

What is the difference between dutasteride and combination brands like Combodart®?

Dutasteride is a single medicine used to treat benign prostatic hyperplasia (BPH). Combodart® is a combination medicine that contains both dutasteride and tamsulosin. The article notes that combination brands like Combodart® may provide quicker and better relief of symptoms than taking either medicine alone.

Can dutasteride impact my ability to have children or my partner's pregnancy?

Yes, dutasteride can potentially harm an unborn baby. Therefore, pregnant women should not handle damaged or leaking capsules. Also, small amounts of dutasteride will be present in your semen while you are taking this medicine. If your partner could become pregnant, it is recommended to use a barrier method of contraception, such as a condom. For further advice, you should speak with your pharmacist or doctor.

Are there any lifestyle changes I can make to improve my prostate symptoms while taking dutasteride?

Yes, you can consider reducing or stopping your intake of caffeine (found in tea, coffee, and cola) and alcohol, as these can worsen your symptoms. If you smoke, stopping smoking may also significantly improve your symptoms because nicotine irritates the bladder. Your doctor can offer advice on quitting smoking.

How should I store dutasteride capsules?

You should keep all medicines, including dutasteride, out of the reach and sight of children. Store them in a cool, dry place, away from direct heat and light.

Leitura adicional e referências

Sobre o autorVer biografia completa

Imagem do autor

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

Sobre o revisor

Imagem do autor

Sid Dajani

Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão prevista: 31 Mar 2027
  • 11 de maio de 2024 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
verificador de elegibilidade para gripe

Pergunte, compartilhe, conecte-se.

Navegue por discussões, faça perguntas e compartilhe experiências em centenas de tópicos de saúde.

Inscreva-se no boletim informativo do Patient

Sua dose semanal de conselhos de saúde claros e confiáveis - escritos para ajudá-lo a se sentir informado, confiante e no controle.

Por favor, insira um endereço de e-mail válido

Ao se inscrever, você aceita nossos Política de Privacidade. Você pode cancelar a inscrição a qualquer momento. Nunca vendemos seus dados.