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Danazol capsules

Clinical author's note Michael Stewart 26/11/2024: Danol® capsules have been discontinued in the UK. At the time of review there are no licensed products containing danazol available in the UK. However danazol is available as a specially manufactured medicine or as an imported medicine. Products are still available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Start taking danazol on the first day of your period unless you have been told otherwise. You can take the capsules either before or after meals.

It is important that you do not become pregnant while on danazol. Follow your doctor's advice about suitable contraception.

About danazol

Tipo de medicamento

A gonadotrophin inhibitor

Usado para

Endometriosis; breast cyst pain

Também chamado de

Danol® (discontinued); Cyclomen® (in Canada)

Disponível como

Cápsulas

Danazol works by altering the levels of some of your body's hormones. It is used to treat a number of different conditions.

Endometriose is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or abdomen. It can cause painful periods and persistent pain in the pelvic area, as well as other symptoms. By altering the levels of your hormones, danazol will help to relieve these symptoms.

Danazol is also prescribed to ease severe pain and tenderness associated with breast cyst disease (where other treatments have proved unhelpful). Breast cysts are small lumps which are found in the breast, but which are not cancerous.

In addition to the two conditions above, danazol is also prescribed by specialist doctors for people with a condition known as hereditary angio-oedema (although it is not licensed for this condition). If you have been prescribed it for this reason, please speak with your doctor if you have any questions about your treatment.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking danazol it is important that your doctor knows:

  • Se você está grávida, tentando ter um bebê ou amamentando.

  • If you have a heart condition.

  • If you have any vaginal bleeding other than your regular period.

  • If you have ever had an unwanted blood clot (thrombosis), or stroke.

  • If you have any of the following conditions: epilepsy, diabetes (diabetes mellitus), high blood pressure, migraine, or a blood fat (lipid) disorder.

  • Se você tiver algum problema com o funcionamento do seu fígado, ou qualquer problema com o funcionamento dos seus rins.

  • If you have either of the following blood disorders: polycythaemia or porphyria.

  • If you know you have a type of cancer which is affected by hormones.

  • Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

  • Se você já teve uma reação alérgica a um medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about danazol, and will also provide you with a full list of side-effects which you could experience from taking it.

  • You should start taking danazol on the first day of your next period unless you have been told otherwise.

  • Your doctor will tell you how many capsules to take each day, and when you should take them. As a guide, for the treatment of endometriosis or breast pain, danazol is usually taken 2-4 times daily for 3-6 months. Take the capsules exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.

  • Swallow the capsules whole with a drink of water - do not chew or open them before you swallow.

  • You can take danazol capsules either before or after meals, but try to take your doses at the same times each day, as this will help you to remember to take them regularly.

  • Se você esquecer de tomar uma dose, tome-a assim que se lembrar (a menos que esteja quase na hora da próxima dose, nesse caso, pule a dose esquecida). Não tome duas doses juntas para compensar uma dose esquecida.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor may want you to have some blood tests during this treatment.

  • It is important that you do not become pregnant while you are on danazol. If appropriate, you and your partner should use a non-hormonal method of contraception, such as a condom. This is because hormonal methods (such as 'the pill' or 'mini pill') will not work. Speak with your doctor if you need further advice about what methods of contraception are suitable for you to use.

  • It is best not to drink alcohol while you are on danazol. This is because drinking alcohol while taking danazol could make you feel sick or short of breath.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with danazol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Danazol side-effects

O que posso fazer se passar por isso?

Sentindo-se mal (náusea), dor de estômago

Stick to simple foods (avoid rich or spicy meals)

Feeling dizzy or tired, eyesight changes

If this happens, do not drive and do not use tools or machines while affected. Let your doctor know about any eyesight changes

Headache, other aches and pains

Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or continues, speak with your doctor

Increased growth of hair (particularly on your body or face), voice changes, hair loss similar to male baldness

Speak with your doctor about this as soon as possible. An alternative treatment may be more suitable for you

Acne, skin rash, muscle cramps, mood changes, changes in your desire for sex, increased appetite and weight changes, irregular menstrual periods, vaginal dryness and irritation, hot flushes, reduced breast size, a feeling that your heart is racing

Se algum desses se tornar problemático, fale com seu médico

Importante: if you experience any of the following rare but possibly serious symptoms, please speak with your doctor straightaway:

  • A severe headache and sickness (nausea and vomiting).

  • Any yellowing of your skin or of the whites of your eyes (jaundice).

  • Any painful swelling of your arms or legs, or sudden chest pain.

  • Any bruising that you can't explain. This could be a sign of a blood disorder.

If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá imediatamente ao departamento de emergência do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines.

If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do site Cartão Amarelo.

Vídeos selecionados para Tratamento de desequilíbrio hormonal

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Leitura adicional e referências

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Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Next review due: 26 Nov 2027
  • 26 Nov 2024 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
flu eligibility checker

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