Aminofilina
Phyllocontin Continus
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 28 Sept 2022
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Aminophylline helps relieve symptoms such as cough, wheeze and shortness of breath.
You will be prescribed two doses of aminophylline each day - take them 12 hours apart.
Swallow the tablets whole - do not crush or chew them.
If you are a smoker or drink alcohol, ask your doctor for advice, as these can affect the amount of the medicine in your blood.
Em resumo
Aminophylline is a bronchodilator medicine used for lung problems like asthma and COPD.
It comes as modified-release tablets, usually taken twice a day, 12 hours apart.
Swallow tablets whole; do not chew, break, or crush them.
Your doctor may adjust your dose based on blood tests.
Keep taking aminophylline unless your doctor tells you to stop.
If your symptoms worsen, contact a doctor or nurse straight away.
If you suspect an overdose, go to A&E immediately.
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About aminophylline
Tipo de medicamento | Xanthine bronchodilator |
Usado para | Lung-related problems such as asthma and chronic obstructive pulmonary disease (COPD); sometimes used to treat heart failure |
Também chamado de | Phyllocontin Continus® |
Disponível como | Modified-release tablets and injection |
Aminophylline is an oral bronchodilator medicine which is prescribed for people with breathing problems, such as asma e doença pulmonar obstrutiva crônica (DPOC). It is a medicine that you take by mouth as a tablet. It is also available as an injection, but this is usually given in a hospital environment. Aminophylline is actually a mixture of a medicine called theophylline, and ethylenediamine. The ethylenediamine is used to improve how well the active medicine, theophylline, dissolves.
This medicine works by opening up the air passages in your lungs so that air can flow into your lungs more freely. This makes breathing easier and helps relieve symptoms such as coughing, wheezing and shortness of breath.
Before taking aminophylline
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking aminophylline it is important that your doctor or pharmacist knows:
Se você está grávida, tentando ter um bebê ou amamentando.
If you have a heart condition or liver problems.
If you have an overactive thyroid gland gland (hyperthyroidism).
Se você tem pressão alta (hipertensão).
Se você tem uma úlcera no estômago.
If you drink alcohol or smoke.
Se você tem epilepsia.
If you are currently unwell with a high temperature.
Se você tem um distúrbio sanguíneo hereditário raro chamado porfiria.
If you have been told you have low levels of potassium in your blood.
If you are taking or using any other medicines or inhalers. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
Se você já teve uma reação alérgica a um medicamento.
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How to take aminophylline
Voltar ao conteúdoBefore starting this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about aminophylline and a full list of side-effects which you may experience from taking it.
Aminophylline is taken twice a day, in the morning and evening. Always try to take your doses 12 hours apart and at the same times each day. For example, at 8 am and 8 pm each day. You can take the tablets before or after meals.
Swallow the tablets whole with a drink of water. Do not chew, break, or crush them.
There are two different strengths of tablet available, and you will be asked to take either one or two tablets for each of your doses. Your dose may be adjusted over the first few weeks, depending on the results of some blood tests. The tests allow your doctor to make sure that you have the dose that helps your condition, but avoids any unwanted symptoms.
Your doctor or pharmacist will tell you what strength of tablet is right for you and how many tablets to take for each dose. Your dose will also be on the label of the pack to remind you.
If you forget to take a dose but it is still within four hours of the time you should have taken it, take a dose as soon as you remember. If it is more than four hours since you should have taken it, do not take the missed dose but do remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoContinue to take aminophylline unless your doctor tells you otherwise. Bronchodilators like aminophylline are usually prescribed long-term.
Try to keep your regular appointments with your doctor. This is so your doctor can review your condition on a regular basis. Your doctor will want to test your blood from time to time to make sure that you are receiving the correct dose and also to check the levels of potassium in your blood.
The amount of aminophylline in your blood should be kept within a certain range. It can vary if you are unwell, or if you start or stop smoking, take other medicines, or if you drink more alcohol than usual. This is because these things interfere with the way aminophylline is handled by your body. Some of these things will increase the amount of medicine in your body, leading to side-effects. Others will reduce it, leading to your treatment not being as effective as it should be.
If at any time you find that your symptoms are getting worse, contact a doctor or nurse for advice straightaway.
If you want to buy any medicines, check with a pharmacist that they are safe for you to take. Some medicines (including the herbal remedy St John's wort) can affect the levels of aminophylline in your blood and should not be taken alongside it without your doctor knowing.
Some vaccines, such as the flu vaccine, may also affect aminophylline levels. Make sure you tell your doctor about any vaccinations you have.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking, as some anaesthetics can interfere with aminophylline.
Aminophylline can be very toxic in overdose. If you suspect that someone has taken more than they should (and especially if it is a child), go to the accident and emergency department of your local hospital straightaway. Take the container with you, even if it is empty.
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Can aminophylline cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with aminophylline. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Comum aminophylline side-effects | O que posso fazer se passar por isso? |
Feeling sick (nausea), upset stomach | Stick to simple foods - avoid rich or spicy meals. Try taking your doses after meals |
Dor de cabeça | Beba bastante água e peça a um farmacêutico que recomende um analgésico adequado. Se as dores de cabeça continuarem, informe seu médico |
A fast heartbeat, difficulty sleeping, feeling shaky or restless, being sick (vomiting) | If these symptoms continue or are severe, speak with your doctor or pharmacist, they could be a sign your dose is too high |
Erupção cutânea com coceira | This may be a sign of an allergic reaction - let your doctor know about this |
Se você sentir quaisquer outros sintomas que acha que podem ser devido a este medicamento, fale com seu médico ou farmacêutico.
How to store aminophylline
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá imediatamente ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio, para que o médico saiba o que foi tomado.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
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Perguntas frequentes
What is the key ingredient in aminophylline that helps with breathing?
Aminophylline is a mixture of the medicine theophylline and ethylenediamine. Theophylline is the active ingredient that works to open up the air passages in your lungs, making breathing easier and relieving symptoms like coughing, wheezing, and shortness of breath.
How often will my blood need to be tested while I'm taking aminophylline?
Your doctor will want to test your blood from time to time to make sure you are receiving the correct dose and to check the levels of potassium in your blood. This is important because the amount of aminophylline in your blood needs to be kept within a certain range to be effective and to avoid unwanted symptoms.
Are there any specific drinks or habits I should be careful about when taking aminophylline?
Yes, factors like drinking alcohol or smoking can interfere with how your body handles aminophylline. Being unwell or taking other medicines can also affect its levels. These changes can either increase the medicine in your body, potentially leading to side-effects, or reduce it, making the treatment less effective.
What should I do if I feel worse despite taking aminophylline as prescribed?
If you notice that your symptoms are getting worse at any time, you should contact a doctor or nurse for advice straightaway.
Can I take other over-the-counter medicines or herbal remedies with aminophylline?
You should always check with a pharmacist before buying any other medicines, including herbal and complementary medicines. Some medicines, such as the herbal remedy St John's wort, can affect the levels of aminophylline in your blood and should not be taken without your doctor's knowledge.
What should I do if I'm preparing for surgery or dental work?
If you are due to have an operation or any dental treatment, you must tell the person carrying out the treatment about all the medicines you are taking, as some anaesthetics can interfere with aminophylline.
What are the signs that my aminophylline dose might be too high?
Certain side-effects like a fast heartbeat, difficulty sleeping, feeling shaky or restless, or being sick (vomiting) could be a sign that your dose is too high. If these symptoms continue or are severe, you should speak with your doctor or pharmacist.
Leitura adicional e referências
- Manufacturer's PIL, Phyllocontin Continus® tablets 225 mg, Phyllocontin Forte Continus® tablets 350 mg; Napp Pharmaceuticals Limited, The electronic Medicines Compendium. Dated May 2019.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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Sobre o autorVer biografia completa

Helen Allen, MPharm
Farmacêutico, Autor Médico
MPharm
Helen Allen se formou como farmacêutica em 1979 e passou 3 anos como autora dos folhetos de informações sobre medicamentos para a EMIS.
Sobre o revisor

Sid Dajani
Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão agendada: 26 de mar de 2027
28 Sept 2022 | Última versão
7 Jun 2013 | Publicado originalmente
Escrito por:
Helen Allen, MPharm

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