Adesivos de Rotigotina
Neupro
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 3 Dez 2024
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Apply one patch every day.
Please keep all your regular appointments with your doctor. You will need tests from time to time to check on your progress.
Occasionally, people using rotigotine have fallen asleep suddenly during the day with little warning of being tired. If you experience this, please do not drive, and make an appointment to see your doctor as soon as possible. Rotigotine can also cause impulsive types of behaviour in some people.
At a glance
Rotigotine patches treat Parkinson's disease and severe restless legs syndrome.
They work by acting like dopamine in the brain, helping to ease symptoms.
Apply one new patch every day to a different skin area, removing the old one.
Avoid applying patches near direct heat sources as this can increase medicine release.
Tell your doctor if you experience sudden sleepiness or changes in behaviour.
Do not stop using the patches suddenly; your doctor will advise on gradual reduction.
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About rotigotine patches
Tipo de medicamento | A dopamine-receptor agonist |
Usado para | Parkinson's disease, restless legs syndrome |
Também chamado de | Neupro® |
Disponível como | Skin patches |
Rotigotine is usually prescribed to treat Doença de Parkinson. Parkinson's disease affects the way your brain co-ordinates the movements of your muscles. A number of cells in a small part of your brain, called the substantia nigra, become damaged and die. These brain cells pass messages down nerves in the spinal cord by producing a chemical called dopamine, and it is these messages which control the muscles of the body. As the cells in the brain are damaged, the amount of dopamine that is produced is reduced. A combination of the reduction of cells and a low level of dopamine in the cells in this part of the brain, causes nerve messages to the muscles to become slowed and abnormal. This produces the main symptoms of Parkinson's disease, which are stiffness, shaking (tremor), and slowness of movement.
Rotigotine is a dopamine-receptor agonist which means that it acts on the same receptors in your brain as dopamine. In effect, it acts like a substitute for dopamine and this helps to ease your symptoms. It may be used alone, or in combination with other medicines to treat Parkinson's disease.
Rotigotine is also used to treat síndrome das pernas inquietas (RLS). This is an uncomfortable feeling in your legs, which gives you the urge to move your legs to get relief. Rotigotine can help when these symptoms are severe enough to cause distress.
Before using rotigotine patches
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start using the patches it is important that your doctor knows:
Se você está grávida ou amamentando.
Se você tiver algum problema com o funcionamento do seu fígado.
Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
Se você já teve uma reação alérgica a um medicamento.
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How to use rotigotine patches
Voltar ao conteúdoBefore you apply a patch, read the manufacturer's printed information leaflet from inside the pack and any additional information your doctor has given to you. These will give you more information about rotigotine and how to use the patches correctly, and it will also provide you with a full list of the side-effects which you may experience.
There are several different strengths of rotigotine patch. Each time you collect a prescription, please check the strength on the box to make sure that you have been given the strength you are expecting. Ask your pharmacist to check for you if you are unsure about anything.
When you first start using the patches you will be given a low-dose patch. The strength of the patch will then be increased each week until your symptoms are controlled.
Apply one patch every day. Try to get into the habit of applying the patches at the same time of day each day. Also, it's important that you remember to remove the 'old' patch before you apply the 'new' patch.
You can put the patches on areas of your body such as the sides of your body, your thighs, hips, tummy (abdomen), shoulder and upper arms.
To make sure the patch sticks well, press the patch down firmly with the palm of your hand for about 30 seconds.
Each time you apply a patch, use a different area of skin to apply the new patch to. Do not use the same area again for at least 14 days.
If you forget to change your patch at your usual time, do it when you remember, and then change this new patch on the next day at your usual time. If a patch comes off accidentally, apply a new patch but then continue to change it at your usual time.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoTry to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. During the first few weeks of treatment in particular, your dose may require adjusting. Rotigotine can cause your blood pressure to fall (particularly in the early days of your treatment) and your doctor will want to check for this. Your doctor could also recommend you have eyesight tests from time to time.
Try to make sure that when you are wearing a patch it does not come into contact with a heat source such as a heating pad, hot water bottle, electric blanket, or a heated water bed. Heated items like these may increase the amount of medicine that is released from the patch. Having long hot baths or sunbathing for long periods of time is also best avoided.
Sometimes people taking medicines like rotigotine can fall asleep suddenly during the day with little or no warning of being tired beforehand. Until you know how you react, take extra care if you drive or operate machinery. If you do find yourself falling asleep suddenly, you should see your doctor as soon as possible for advice, and avoid driving or using tools and machines in the meantime.
Treatment with medicines like rotigotine can sometimes cause problems with tipos de comportamento impulsivo. Se você notar qualquer mudança no seu comportamento, como um desejo aumentado de jogar, comer compulsivamente, gastar excessivamente ou um aumento no desejo sexual, você deve informar seu médico o mais rápido possível.
Mantenha-se o mais ativo possível e exercite-se regularmente tanto quanto puder. Você pode caminhar mais devagar do que antes, mas uma caminhada diária é um bom exercício e pode ajudar a soltar os músculos rígidos.
If you are a driver you should tell the DVLA and your insurance company if you have Parkinson's disease. Depending on the severity of symptoms and the medicines that you are taking, you may still be allowed to drive following a medical assessment.
If you are due to have an operation or any medical treatment, please tell the person carrying out the treatment that you are using skin patches. This is particularly important if you are due to have MRI (magnetic resonance imaging) or cardioversion, as any patches will need to be removed before these procedures.
There is a small increased risk of skin problems developing in people with Parkinson's disease, although the cause of this is unclear. It is a good idea to check your skin from time to time for any unusual areas of skin, and to speak with your doctor if you are concerned.
Keep using the patches until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor will want you to reduce the strength of the patches gradually if you need to stop treatment.
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Can rotigotine patches cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with rotigotine. You will find a full list in the manufacturer's information leaflet supplied with the patches. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common rotigotine side-effects (these affect more than 1 in 10 people) | O que posso fazer se passar por isso? |
Dor de cabeça | Beba bastante água e peça ao seu médico ou farmacêutico que recomende um analgésico adequado. Se as dores de cabeça continuarem, informe o seu médico |
Sentindo-se mal (náusea) ou vomitando (vômito) | Mantenha refeições simples ou sem sabor (evite alimentos ricos e condimentados) |
Skin reactions or itching where the patch has been applied | Protect the area from sunshine until it has healed |
Common rotigotine side-effects (these affect fewer than 1 in 10 people) | O que posso fazer se passar por isso? |
Feeling drowsy or sleepy, falling asleep suddenly | If this happens, do not drive and do not use tools or machines. Speak with your doctor |
Feeling dizzy or faint (due to changes in your blood pressure) | Getting up and moving around more slowly may help. If you begin to feel dizzy, lie down so that you do not faint; then sit for a few moments before standing. This usually passes as your body gets used to the patches, but in the meantime do not drive and do not use tools or machines |
Difficulties sleeping, abnormal thinking and behaviour, the sensation of having a 'thumping heart' (palpitations), hiccups, constipation, loss of weight, swollen legs and ankles, feeling irritable, indigestion | Se algum desses se tornar problemático, fale com seu médico |
Allergic reactions | If severe, speak with a doctor straightaway |
Impulsive types of behaviour | Informe seu médico sobre isso o mais rápido possível |
If you experience any other symptoms which you think may be due to the patches, please speak with your doctor or pharmacist for further advice.
How to store rotigotine patches
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
If you suspect that you or someone else might have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
Este medicamento é para você. Não o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Se você comprar qualquer medicamento, sempre verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
If you have any questions about this medicine, please ask your pharmacist for advice.
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Perguntas frequentes
What is the main role of rotigotine in treating Parkinson's disease?
Rotigotine acts similarly to dopamine on your brain's receptors. In Parkinson's disease, brain cells that produce dopamine become damaged, leading to reduced dopamine levels. Rotigotine substitutes for this missing dopamine, helping to ease symptoms like stiffness, shaking, and slow movement.
Are there specific areas on the body where I should apply the rotigotine patch?
Yes, you can apply the rotigotine patch to various parts of your body. Suitable areas include the sides of your body, your thighs, hips, tummy (abdomen), shoulder, and upper arms. It's important to use a different skin area each time you apply a new patch, and not to reuse the same area for at least 14 days.
How can I ensure the patch sticks properly to my skin?
To make sure a rotigotine patch adheres well, you should press it down firmly with the palm of your hand for about 30 seconds after applying it.
What should I do if my rotigotine patch comes off unexpectedly?
If a rotigotine patch accidentally comes off, apply a new patch immediately. However, you should then continue to change this new patch at your usual time the following day.
What kind of environmental factors should I avoid while wearing a rotigotine patch?
While wearing a rotigotine patch, you should avoid contact with heat sources such as heating pads, hot water bottles, electric blankets, or heated water beds, as these can increase the amount of medicine released from the patch. It's also best to avoid long hot baths or extended sunbathing.
Can rotigotine patches affect my eyesight?
The article states that your doctor might recommend eyesight tests from time to time during your treatment with rotigotine. This suggests that there could be potential visual effects that your doctor would monitor.
How should I dispose of used rotigotine patches or any unwanted medicine?
You should not keep out-of-date or unwanted medicines, including used patches. Take them to your local pharmacy, which will dispose of them for you safely.
Leitura adicional e referências
- Manufacturer's PIL, Neupro® 4 mg, 6 mg, 8mg /24 hr Transdermal Patch; UCB Pharma Limited, The electronic Medicines Compendium. Dated January 2024.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista: 4 de Dez 2027
3 Dez 2024 | Última versão

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