Rivastigmina
Alzest, Exelon, Prometax
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 29 Dez 2022
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Rivastigmine helps ease the symptoms of memory loss and dementia.
You will be given a small dose when you first start treatment. This will gradually be increased.
If you are taking the capsules or liquid medicine, take your doses after a meal.
If you are using the patches, make sure you remove the old patch before applying a new one.
At a glance
Rivastigmine is a medicine used to treat symptoms of dementia associated with Alzheimer's or Parkinson's disease.
It aims to slow the progression of symptoms, not cure the condition, by increasing a brain chemical.
A specialist doctor will prescribe rivastigmine, which comes as capsules, liquid, or skin patches.
Take capsules or liquid with meals, or apply a new patch daily to non-hairy skin.
Do not stop taking it suddenly; if you miss doses for several days, talk to your doctor.
Common side-effects include feeling sick, indigestion, diarrhoea, or dizziness.
Tell your doctor if you have liver, kidney, heart, or breathing problems before starting it.
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About rivastigmine
Tipo de medicamento | Anti-dementia medicine (an acetylcholinesterase inhibitor) |
Usado para | Dementia associated with Alzheimer's disease or Parkinson's disease |
Também chamado de | Almuriva®; Alzest®; Erastig®; Exelon®; Nimvastid®; Prometax® |
Disponível como | Capsules, oral liquid medicine and skin patches |
Rivastigmine is used to treat the symptoms of dementia, such as memory loss. It is prescribed for people who have dementia which is associated with Alzheimer's disease or Doença de Parkinson.
Rivastigmine cannot cure dementia, but it can slow down the progression of the symptoms in some people. It works by increasing the level of a natural chemical called acetylcholine. This is a chemical which allows nerve cells in the brain to communicate with each other, and it is known that people with dementia have low levels of it. The symptoms of dementia can be improved by increasing the levels of acetylcholine.
Rivastigmine will be prescribed by a specialist doctor. If you are a caregiver, please read this leaflet on behalf of the person who is receiving rivastigmine.
Before taking rivastigmine
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking rivastigmine it is important that your doctor or pharmacist knows:
Se você tiver problemas no fígado ou nos rins.
Se você tem uma condição cardíaca.
If you have any problems with your breathing, such as asthma or chronic obstructive pulmonary disease (COPD).
If you have any problems passing urine.
If you have ever had a stomach (gastric) or duodenal ulcer.
If you have ever had fits (convulsions or seizures).
Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
Se você já teve uma reação alérgica a um medicamento.
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How to take rivastigmine
Voltar ao conteúdoBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about rivastigmine and a full list of side-effects which you may experience from it.
Your caregiver will help you take your medicine exactly as your doctor has told you. It is usual to be prescribed two doses to take each day. Your dose will be written on the label of your pack to remind you.
There are several different strengths of rivastigmine capsules and patches available, so make sure the product you have been given is the strength you were expecting. If you are unsure, ask your pharmacist for advice.
Ideally the capsules or liquid medicine should be taken with, or soon after, your breakfast and your evening meal. Try to take your doses at the same times each day as this will help you to remember to take them.
If you have been prescribed capsules to take, you should swallow the capsule whole without chewing or crushing it. Taking your doses with a small drink of water may help.
Se você esquecer de tomar uma dose, tome-a assim que se lembrar, a menos que esteja quase na hora da sua próxima dose, nesse caso, pule a dose esquecida. Não tome duas doses juntas para compensar uma dose esquecida.
If you forget to take rivastigmine for several days, talk with your doctor before starting to take it again, as you may need to re-start your treatment on a lower dose.
If you have been prescribed skin patches, you will be asked to apply one patch each day. Make sure the previous day's patch is removed before you apply a new patch. If the patches cause any irritation to your skin, you should let your doctor know about this.
Taking rivastigmine oral liquid medicine
Read the manufacturer's instructions for the medicine you have been given.
Open the bottle and remove the oral dosing syringe and bottle adaptor provided.
Push the nozzle of the syringe into the bottle adaptor and insert it firmly into the top of the bottle.
Turn the bottle upside down.
Pull the plunger on the syringe a little way and push back up to get rid of any air bubbles. Then pull the plunger down to withdraw the required amount of medicine. Re-check your dose once you have removed the syringe from the bottle.
You can swallow the medicine straight from the syringe, or you can stir it into a glass of water to drink it.
When you have finished taking your dose, wipe the outside of the syringe with a tissue. The syringe can be cleaned in warm, soapy water.
Applying rivastigmine (Exelon®) patches
Open a packet and remove the patch from inside.
Apply the patch to an area of non-hairy skin on your back, upper arm, or chest (but not to your breast area). Press down on the patch with the palm of your hand for around 30 seconds. This will make sure it sticks firmly in place.
After 24 hours, remove the patch and do not use the same area of skin to apply another patch to for at least 14 days.
Repeat this process each day, removing the previous day's patch before applying a new patch.
If you forget to apply a new patch for more than three days, talk with your doctor before applying another patch, as you may need a lower dose.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoWhen starting your treatment your doctor will give you a small dose and then gradually increase the dose. This allows your doctor to make sure that you have the dose that helps your condition and avoids any unwanted side-effects.
Your doctor will want to check your progress every few weeks to make sure the dose is right for you and that you are getting benefit from this treatment. Try to keep these regular doctor's appointments.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking rivastigmine. This is because rivastigmine may affect the amount of any anaesthetic you may need.
If you buy any medicines, always check with a pharmacist that they are safe to take with your other medicines. Some medicines can interfere with the way rivastigmine works.
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Can rivastigmine cause problems?
Voltar ao conteúdoAlong with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with rivastigmine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of taking a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common rivastigmine side-effects | O que posso fazer se passar por isso? |
Sentindo-se mal (náusea) ou vomitando, indigestão, dor de estômago (dor abdominal) | Let your doctor know if this happens, as your treatment may need reviewing |
Diarreia | Drink plenty of water to replace any lost fluids. Let your doctor know if it continues |
Sentindo-se tonto ou cansado | Be especially careful if you are using any tools or machines |
Dor de cabeça | Beba bastante água e peça ao seu farmacêutico que recomende um analgésico adequado. Se as dores de cabeça continuarem, fale com o seu médico |
Loss of appetite, losing weight, feeling anxious or agitated, trembling, falling, sweating, and skin reactions (with the patches) | Se algum desses se tornar problemático, fale com seu médico |
Se você sentir quaisquer outros sintomas que acha que podem ser devido a este medicamento, fale com seu médico ou farmacêutico.
How to store rivastigmine
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Once opened, a bottle of the medicine only keeps for one month. Do not store it or use it after this time.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

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Perguntas frequentes
What is the main goal of rivastigmine treatment for dementia?
Rivastigmine is used to help manage the symptoms of dementia, such as memory loss, for people with Alzheimer's disease or Parkinson's disease. While it cannot cure dementia, it can help slow down the progression of these symptoms in some individuals.
How does rivastigmine work in the brain to help with dementia symptoms?
Rivastigmine works by increasing the levels of a natural brain chemical called acetylcholine. This chemical is essential for nerve cells to communicate in the brain, and people with dementia often have low levels of it. By increasing acetylcholine, rivastigmine can improve dementia symptoms.
How should I take rivastigmine capsules or liquid medicine to get the best effect?
It is usually recommended to take rivastigmine capsules or liquid medicine twice a day, ideally with or shortly after breakfast and your evening meal. Taking your doses at the same time each day can help you remember. Swallow capsules whole with a drink of water. If you're using the liquid, you can take it directly from the syringe or stirred into water.
What should I do if I forget to take a dose of rivastigmine?
If you forget a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Never take two doses at once to make up for a forgotten one. If you miss several days of treatment, you should speak with your doctor before starting again, as you might need to begin on a lower dose.
Are there any specific instructions for applying rivastigmine skin patches?
Apply one patch each day to a non-hairy area of skin on your back, upper arm, or chest (avoiding the breast area). Press the patch firmly for about 30 seconds to ensure it sticks. Remember to remove the previous day's patch before applying a new one, and avoid using the same skin area for a new patch for at least 14 days. If the patches cause skin irritation, inform your doctor.
What should I tell my doctor or pharmacist before starting rivastigmine?
Before starting rivastigmine, it's important to inform your doctor or pharmacist if you have any liver or kidney problems, a heart condition, breathing issues like asthma or COPD, problems passing urine, a history of stomach or duodenal ulcers, or have ever experienced fits or seizures. Also, mention all other medicines you are taking, including over-the-counter or herbal remedies. Let them know if you've had an allergic reaction to any medicine in the past.
How will my doctor decide the correct dose of rivastigmine for me?
When you start treatment, your doctor will prescribe a small dose and gradually increase it. This allows them to find the most effective dose for your condition while minimising unwanted side-effects. Your progress will be checked regularly to confirm the dose is right and that you are benefiting from the treatment.
What should I do if I experience common side-effects like feeling sick or an upset tummy?
Common side-effects such as nausea, vomiting, indigestion, or tummy pain often improve over the first few days. If these continue or become troublesome, you should let your doctor know, as your treatment may need reviewing. For diarrhoea, drink plenty of water to prevent dehydration, and inform your doctor if it persists.
Leitura adicional e referências
- Manufacturer's PIL, Rivastigmine Mylan 1.5 mg, 3 mg, 4.5 mg, 6 mg Hard Capsules; Mylan, The electronic Medicines Compendium. Dated April 2021.
- Manufacturer's PIL, Rivastigmine Rosemont 2 mg/ml Oral Solution; Rosemont Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated September 2019.
- Manufacturer's PIL, Exelon® 4.6 mg/24h, 9.5 mg/24h, 13.3 mg/24h Transdermal Patch; Novartis Pharmaceuticals UK Ltd, The electronic Medicines Compendium. Dated November 2020.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 28 Jun 2027
29 Dez 2022 | Última versão

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