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Rimegepant para dor de cabeça por enxaqueca

Vydura

This medicine can treat an active migraine attack and prevent future attacks from happening.

For treatment of a migraine attack once it has started, the recommended dose is one 75 mg tablet as needed and no more than once daily.

To prevent migraines the dose is one tablet every other day.

The maximum dose is one 75 mg tablet every day.

The most common side-effect is feeling sick (nausea), if this happens try taking your dose with a meal or snack.

Em resumo

  • Rimegepant (Vydura) treats and prevents migraine headaches in adults.

  • It is an 'melt-in-the-mouth' tablet that dissolves in your mouth.

  • To treat a migraine, you can take one tablet daily if needed.

  • For prevention, take one tablet every other day.

  • Tell your doctor if you are pregnant, have kidney/liver problems, or take other medicines.

  • Nausea is a common side-effect, usually improving as your body adjusts to the medicine.

  • Seek medical attention for severe allergic reactions like shortness of breath or facial swelling.

About rimegepant for migraine headache

Tipo de medicamento

CGRP-receptor blocker

Usado para

Treating and preventing migraine headaches in adults aged 18 years or older

Também chamado de

Vydura®

Disponível como

'Melt-in-the-mouth' orodispersible tablets

Rimegepant can be used to treat an active enxaqueca or to prevent migraine attacks from happening. Although it is not known exactly how rimegepant works, it is known to block the action of a substance called calcitonin gene-related peptide (CGRP) by attaching to its receptor sites in the brain. People with migraine may have raised levels of CGRP. By blocking the effects of CGRP, rimegepant can stop an active migraine attack and also reduce the number of attacks over time.

In people with migraine, it is thought that some chemicals in the brain increase in activity. As a result, parts of the brain then send out confused signals which result in the symptoms of headache and sickness (náusea e vômito). Why people with migraine should develop these chemical changes is not clear, but for some people there may be things which trigger an attack, like certain foods or drinks.

Before taking rimegepant

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking rimegepant it is important that your doctor knows:

  • Se você está grávida, tentando ter um bebê ou amamentando.

  • If you have any problems with the way your kidneys work or the way your liver works.

  • Se você já teve uma reação alérgica a um medicamento.

  • Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

How to take rimegepant tablets

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer’s leaflet will give you more information about rimegepant and a full list of side-effects which you may experience from taking it.

  • Take rimegepant exactly as your doctor tells you to. If you are taking rimegepant to prevent migraine attacks then the usual dose is one 75 mg tablet every other day.

  • If you are taking rimegepant to treat a current migraine headache then you can take one tablet every day if required. The maximum dose is one 75 mg tablet per day.

  • The tablet is orodispersible which means it will dissolve in the mouth without the need to drink water.

  • Take care to handle the tablet as little as possible and make sure your hands are dry. Peel back the foil on the blister, do not try to push the tablet through the foil. Place the tablet on, or under, your tongue and allow it to dissolve.

  • It is not important whether you take your dose before or after food.

  • If you forget to take a dose, take it as soon as you remember unless your next dose is nearly due, in which case, leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed one.

Obtendo o máximo do seu tratamento

  • Tente manter todas as suas consultas regulares com o seu médico. Isso é para que o seu médico possa verificar o seu progresso.

  • If you find that rimegepant does not relieve or prevent your migraines, make an appointment to discuss this with your doctor, as an alternative medicine may be more effective for you.

  • It may help to keep a migraine diary. Note down when and where each migraine attack started, what you were doing, and what you had eaten that day. A pattern may emerge and it may be possible for you to avoid some of the things that trigger your migraine attacks.

  • Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as ibuprofen) in addition to rimegepant. Your doctor will advise you about this if it is recommended for you.

  • Some medicines can affect how well rimegepant works. Your doctor or pharmacist will advise you on this, and you will find a full list in the manufacturer's information supplied with your pack.

  • If you buy any medicines, check with your doctor or a pharmacist that they are suitable for you to take with rimegepant. You should not take the herbal medicine St John's wort while you are being treated with rimegepant..

  • Some people who get frequent migraine attacks are in fact getting medication-induced headache. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers too often. If you use painkillers on more than two days a week on a regular basis, you may be at risk of this. You should talk with your doctor if you suspect it.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking rimegepant.

Can rimegepant cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with rimegepant. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common rimegepant side-effects (affecting fewer than 1 in 10 people)

O que posso fazer se passar por isso?

Sentindo-se enjoado (náusea)

Stick to simple foods, avoid rich or spicy foods. Try taking your dose with a meal

Stop using rimegepant and seek medical attention if you develop any signs of a severe reação alérgica, such as shortness of breath, facial swelling or a severe skin rash.

Se você sentir quaisquer outros sintomas que acha que podem ser devido a este medicamento, fale com seu médico ou farmacêutico.

How to store rimegepant tablets

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

  • Once the foil blister is opened do not store the tablet for later use.

Informações importantes sobre todos os medicamentos

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

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Perguntas frequentes

What is CGRP and why is blocking it important for migraine?

CGRP stands for calcitonin gene-related peptide. People with migraine may have raised levels of this substance. Rimegepant works by blocking the action of CGRP at its receptor sites in the brain, which can stop an active migraine attack and reduce the frequency of attacks over time.

Are there any specific medical conditions that might prevent me from taking rimegepant?

Yes, it's important for your doctor to know if you have any problems with your kidneys or liver, as these conditions might affect whether rimegepant is suitable for you or if extra care is needed during treatment.

Can I take other medications, including over-the-counter remedies or herbal supplements, with rimegepant?

It's important to inform your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. Some medicines can affect how well rimegepant works. Specifically, you should not take the herbal medicine St John's wort while being treated with rimegepant.

What should I do if I experience nausea from rimegepant?

Nausea is a common side-effect affecting fewer than 1 in 10 people. If you experience feeling sick, you can try sticking to simple foods, avoiding rich or spicy foods, and taking your dose with a meal. If it continues or becomes troublesome, speak with your doctor or pharmacist.

How should I dispose of any leftover or expired rimegepant tablets?

Você não deve manter medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que os descartará de forma segura para você.

Leitura adicional e referências

Sobre o autorVer biografia completa

Imagem do autor

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

Sobre o revisorVer biografia completa

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Dr Krishna Vakharia, MRCGP

Diretor Médico de Saúde, Optum UK

MBChB, MRCGP(2013), BMedSci (hons), DFSRH, DRCOG, PGDipDerm (Distn)

Dr. Krishna Vakharia é uma médica de clínica geral do NHS. Ela também é examinadora regular do Diploma de Pós-Graduação em Dermatologia Prática na Universidade de Cardiff, além de ser a Diretora Médica de Saúde na Optum UK.

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