Mefloquine for malaria prevention

About mefloquine

Mefloquine tablets help to protect you from malaria when you travel to areas where this can be a problem. Malaria is a serious infection. It is common in tropical countries such as parts of Africa, Asia, South and Central America, and the Middle East. Malaria is a disease which is passed on to humans by infected mosquitoes. A parasite called plasmodium lives inside the stomachs of infected female mosquitoes and is passed on to humans by a bite. Mefloquine works by killing the parasites passed into your body from the bites of the infected mosquitoes.

Como o padrão da malária varia de acordo com a parte do mundo para a qual você está viajando, bem como a estação do ano e o tipo de atividade que você planejou, você deve sempre obter os conselhos mais recentes sobre prevenção da malária com seu médico, farmacêutico ou organizador de viagens. Uma viagem de mochila nas costas pode exigir medidas preventivas diferentes contra a malária em comparação com aquelas necessárias para uma viagem de negócios a uma cidade.

Mefloquine tablets are not available on the NHS, although you will require a prescription from a doctor to obtain them. You will be given a private (non-NHS) prescription to take to your local pharmacy, and you will be asked to pay for the tablets when they are supplied.

Mefloquine can sometimes be given to treat malaria in people who have become infected. This leaflet does not contain information about this, but your doctor can give you more information if you have been prescribed it for this reason.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking mefloquine it is important that your doctor or pharmacist knows:

• Se você está grávida, tentando ter um bebê ou amamentando.

• If you have epilepsy or have ever had fits (convulsions).

• Se você tem uma condição cardíaca.

• If you have ever had depression, severe anxiety, or any other mental health problem.

• Se você tiver algum problema com o funcionamento do seu fígado ou com o funcionamento dos seus rins.

• If you have had Blackwater fever (a complication of malaria infection).

• Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

• If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to a medicine called quinine.
  

• Before you take mefloquine, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mefloquine. It will also provide you with a full list of the side-effects which you may experience from taking it and what to do if you experience them.

• Take the tablets exactly as your doctor tells you to. The dose to prevent malaria in an adult is one 250 mg tablet once a week. Your dose will be printed on the label of the pack to remind you. (If you have malaria and you are taking mefloquine to treat it, your dose will be different to this.) If you are giving mefloquine to a child, the dose prescribed will depend on the weight of your child. Check the label carefully to make sure you are giving the correct dose.

• Start taking the course of tablets 2-3 weeks before you travel and continue to take them for four weeks after you return. Take the tablet on the same day of the week. If you develop any side-effects in the 2-3 weeks before you travel, speak with your doctor for further advice.

• Swallow the tablet with a drink of water during a mealtime (or just after a snack). If you prefer, the tablet can be crushed and mixed with a little food, such as jam or honey, to make it easier to swallow.

• If you forget to take a dose, take it as soon as you remember and then continue with your next dose on the usual day. Do not take two doses at the same time. You must complete the full course of tablets unless you are told otherwise by a doctor.

• These tablets will help prevent you from getting malaria, but it is also important that you take the following precautions against being bitten by mosquitoes:
  

  • Cubra as áreas descobertas dos seus braços e pernas com roupas de mangas compridas e folgadas, calças compridas e meias. Isso é especialmente importante se você estiver ao ar livre após o pôr do sol, pois é quando os mosquitos se alimentam.

  • Use um spray repelente de insetos eficaz em suas roupas e em qualquer área da sua pele que esteja exposta. Se você também estiver usando protetor solar, aplique o protetor solar primeiro e o repelente de insetos depois.

  • Borrife o quarto com um inseticida todas as noites, algumas horas antes de ir para a cama. Verifique suas áreas de dormir em busca de mosquitos - preste atenção especial aos móveis e áreas sob sua cama onde os insetos podem se esconder.

  • Se você estiver dormindo em um quarto sem tela, use um mosquiteiro impregnado com inseticida.

• It is possible that mefloquine may make you feel dizzy and affect your balance. These effects may continue for a while, even after you have stopped mefloquine. Make sure you know how you react before you drive and before you use machines or tools.

• Your doctor will discuss with you the possibility of other unwanted side-effects. If you develop any changes in your moods, thoughts or behaviour, you should see your doctor before your next dose is due so that you can be given an alternative antimalarial medicine.

• If you have been advised to have an oral vaccine to protect you against typhoid, you should arrange to have this at least three days before you start taking mefloquine. This is because mefloquine can stop the vaccine from working properly.

• If you buy any other medicines to take, check with a pharmacist that they are safe to take alongside mefloquine.

• Se você se sentir mal ou desenvolver uma temperatura alta (febre) ou sintomas semelhantes aos da gripe enquanto estiver viajando ou dentro de um ano (especialmente se for dentro de três meses) após retornar para casa, você deve consultar seu médico imediatamente. Isso é importante, mesmo que você tenha tomado seus comprimidos antimaláricos corretamente.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with mefloquine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, discuta-os com seu médico ou farmacêutico, que poderá aconselhá-lo melhor.

• Mantenha todos os medicamentos fora do alcance e da vista das crianças.

• Armazene em local fresco e seco, longe de calor e luz diretos.