Creme de aciclovir
Lipsore, Virasorb, Zovirax
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 5 Nov 2024
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Use aciclovir cream five times a day for at least five days.
To avoid spreading the infection, wash your hands before and after applying aciclovir. Remember infection can also spread to others.
Do not share the same tube of cream with other people.
At a glance
Aciclovir cream is an antiviral medicine used to treat cold sores and genital herpes.
It works by stopping the herpes simplex virus from multiplying.
Start using the cream as soon as symptoms appear and apply it five times a day.
Wash your hands before and after applying the cream to prevent spreading the virus.
Common side-effects include flaking, itchy skin, or a burning sensation.
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About aciclovir cream
Tipo de medicamento | An antiviral cream |
Usado para | Treatment of cold sores and genital herpes |
Também chamado de | Acyclovir (in US); Lipsore®; Virasorb®; Zovirax® |
Disponível como | Creme |
Aciclovir is an antiviral agent. It works by attacking the herpes simplex virus, of which there are two types:
Type 1 herpes simplex virus is the usual cause of herpes labial around the mouth. It also causes up to half of the cases of genital herpes.
Type 2 herpes simplex virus usually only causes herpes genital. It can sometimes cause cold sores.
Aciclovir does not kill the herpes simplex virus, but it does prevent it from multiplying. This means that, although it may have little effect on existing blisters, it can prevent them from getting worse. If you use aciclovir cream as soon as your symptoms start then it will reduce the severity and duration of the symptoms. Aciclovir cream is available on prescription for the treatment of cold sores and genital herpes infections. You can also buy some brands without a prescription in order to treat cold sores.
There are other preparations of aciclovir available which are not dealt with by this medicine leaflet. See the separate leaflets called Aciclovir para infecções virais e Pomada oftálmica de Aciclovir for more information about other formulations of aciclovir.
Before using aciclovir cream
Voltar ao conteúdoTo make sure that this is the right treatment for you, before you start using aciclovir cream it is important that your doctor or pharmacist knows:
If you are pregnant. This is because, if you are expecting a baby, medicines should only be used on the advice of a doctor.
If your immune system is not working as well as it should (for instance, if you have HIV ou AIDS). This is because you may need additional antiviral treatment.
Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
If you have ever had an allergic reaction to a medicine or skin product.
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How to apply aciclovir cream
Voltar ao conteúdoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using aciclovir cream and will provide you with a full list of the side-effects which you could experience from using it.
Apply the cream five times a day. The best way to do this is to use it every four hours during the day (suggested times are 7 am, 11 am, 3 pm, 7 pm and 11 pm). Dab the cream on to the area rather than rubbing it in. This will minimise any damage to the blisters, which could cause pain and spread the virus around.
Start using the cream at the first sign of infection (for instance, when you first feel your skin tingling) and continue to use it for five days. This is often sufficient time for the sore to heal but you can continue to use the cream for a further five days if needed. Remember to wash and dry your hands before and after using aciclovir, to prevent spreading any infection.
If you forget to use the cream, apply it as soon as you remember and then continue using it again at your usual times.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoTry to keep the areas affected by blisters as clean and dry as possible and only touch the sores when you apply the cream.
Aciclovir cream is not intended for use in your mouth or vagina, or near your eyes. This is because it may irritate these parts of your body. If you have sores in any of these areas, you should make an appointment to see your doctor, as alternative preparations can be prescribed which will be suitable for you to use.
When you have a cold sore you should not kiss anyone or allow anyone to come into skin contact with the sore. In particular, avoid kissing newborn babies and anyone who has a poor immune system. When you have no symptoms, you are not usually infectious.
Genital herpes simplex virus is very contagious when blisters are present. You should not have sex from the time your symptoms first start until they are fully over, as there is a high chance of passing on the virus.
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Can aciclovir cream cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with creams containing aciclovir. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Aciclovir cream side-effects (these affect fewer than 1 in 10 people) | O que posso fazer se passar por isso? |
Flaking, itchy or dry skin, burning or stinging when applying the cream | These effects do not usually last for long but if any become troublesome speak with your doctor or pharmacist |
Se você experimentar quaisquer outros sintomas que você acha que podem ser devido ao creme, por favor, fale com seu médico ou farmacêutico para mais conselhos.
How to store aciclovir cream
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Check the label to see how long the cream can be kept once the pack has been opened.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Esta preparação é para uso apenas na pele. Se você suspeitar que alguém engoliu uma quantidade por acidente, entre em contato com o departamento de emergência do hospital local para obter orientação.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está usando.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

Inseguro sobre misturar medicamentos?
Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.
Perguntas frequentes
What is the main difference between aciclovir cream and other medications for herpes?
Aciclovir cream is an antiviral agent that specifically prevents the herpes simplex virus from multiplying. While it may have little effect on existing blisters, it can stop them from worsening and reduce the severity and duration of symptoms if used early. Other forms of aciclovir, such as tablets or eye ointment, are used for different viral infections or in different areas of the body and are not covered by this leaflet.
How soon should I apply aciclovir cream after noticing cold sore symptoms?
You should start using aciclovir cream as soon as you notice the first signs of infection, such as a tingling sensation in your skin. Early application helps to reduce the severity and duration of symptoms.
How long should I continue to use the aciclovir cream?
You should typically use the cream for five days. This is usually enough time for the sore to heal. However, if needed, you can continue to use the cream for an additional five days.
Are there any specific areas of the body where I should avoid using aciclovir cream?
Yes, aciclovir cream is not meant for use inside your mouth, in your vagina, or near your eyes, as it can cause irritation. If you have sores in these areas, you should see your doctor for alternative treatments.
What should I do if the side effects of aciclovir cream, like flaking or stinging, don't go away?
While flaking, itching, dry skin, or a burning/stinging sensation are common side effects that usually improve as your body adjusts, you should speak with your doctor or pharmacist if these effects continue or become troublesome.
Is it safe to use aciclovir cream if I am pregnant or have a weakened immune system?
If you are pregnant, aciclovir cream should only be used if advised by a doctor. If your immune system is not working well, for example due to HIV or AIDS, you should inform your doctor as you might need additional antiviral treatment.
Leitura adicional e referências
- Manufacturer's PIL, Zovirax® Cream; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated November 2020.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 8 de nov de 2027
5 Nov 2024 | Última versão

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