About medroxyprogesterone

Medroxyprogesterone belongs to a group of medicines called progestogens, which are female hormones.

When it is prescribed to help problems such as fluxo intenso, painful, irregular or missed periods, it works by replacing or supplementing the naturally produced female sex hormone called progesterone.

Medroxyprogesterone is also used for endometriose. Endometriosis is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or tummy (abdomen). The cells in this tissue need oestrogen (another female sex hormone) to grow and survive. Medroxyprogesterone reduces the effect of oestrogen on these cells which causes them to 'shrink'. This means the patches of endometriosis also shrink.

Medroxyprogesterone is also prescribed (although at higher doses than in the conditions mentioned above) to help treat some cancers, particularly câncer endometrial.

Medroxyprogesterone is also available as an injection to prevent pregnancy, and as tablets (in combination with an oestrogen) for hormone replacement therapy (HRT) during the menopause. There are other medicine leaflets available which will give you more information about medroxyprogesterone when it is used for these reasons. See the separate leaflets called Injeção de medroxiprogesterona para contracepção e Estrogênio e progestógeno para TRH.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking medroxyprogesterone tablets, it is important that your doctor knows:

• Se você está grávida ou amamentando.

• Se você tem um problema com suas artérias, chamado de doença arterial.

• Se você tem uma condição cardíaca.

• If you have any of the following conditions: migraines, asthma, epilepsy, diabetes, or high blood pressure.

• Se você tiver qualquer sangramento vaginal além do seu período menstrual normal.

• Se você já teve um coágulo de sangue nas pernas ou pulmões.

• If you have had any problems with the way your liver works, or if you have any problems with the way your kidneys work.

• Se você já teve depressão.

• If you have ever had breast cancer, or a cancer that you have been told is dependent on a sex hormone (unless this is why you have been prescribed medroxyprogesterone).

• Se você tem um distúrbio sanguíneo hereditário raro chamado porfiria.

• Se você já teve uma reação alérgica a um medicamento.

• Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
  

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack of tablets. It will give you more information about medroxyprogesterone and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take medroxyprogesterone tablets exactly as your doctor tells you to. There are several strengths of tablets, so it is a good idea to make sure you have been given the same strength each time you collect a fresh supply. If you are unsure about this, ask your pharmacist to check the strength for you.

• Your dose will depend on what you are being treated for. Your doctor will tell you how many tablets to take for each dose, and how often to take them. You may be asked to take the tablets every day, or only on certain days of your monthly cycle. The dose will also be printed on the label of the pack of tablets to remind you about what the doctor said to you but, if you are still unclear about how to take the tablets, you should ask your pharmacist to explain it to you again.

• You can take medroxyprogesterone tablets either before or after meals. It is advisable to swallow the tablets with a drink of water.

• Try to take your doses at the same time of day each day, as this will help you to remember to take medroxyprogesterone regularly. If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose and take the next dose as normal). Do not take two doses together to make up for a forgotten dose.

• Procure manter seus compromissos regulares com seu médico. Assim, ele pode acompanhar seu progresso. Além disso, lembre-se de cumprir as consultas de rotina para exames de mama e Papanicolau.

• These tablets are not for preventing pregnancy. If you need contraception you should discuss this with your doctor. It is important that you do not become pregnant whilst taking medroxyprogesterone as this treatment may harm your unborn baby.

• If you have diabetes you may need to check your blood glucose more frequently, as the tablets can affect the levels of sugar in your blood. Your doctor will advise you about this.

• It is best to avoid smoking and drinking too much alcohol while taking medroxyprogesterone. If you are a smoker and you would like advice on how to quit, speak with your doctor or pharmacist.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with medroxyprogesterone tablets. You will find a full list in the manufacturer's information leaflet that has been given to you. The unwanted effects may improve as your body adjusts to the new medicine, but speak with your doctor, nurse or pharmacist if any of the following continue or become troublesome.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, fale com seu médico ou farmacêutico para mais orientações.

• Mantenha todos os medicamentos fora do alcance e da vista das crianças.

• Armazene em local fresco e seco, longe de calor e luz diretos.