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Comprimidos de Cabergolina

Dostinex, Cabaser

Cabergoline should be taken with food.

It can cause dizziness, especially during the first few days of treatment.

Each time you collect a fresh supply, check to see if the tablets look the same as you have had before. If they are different, discuss this with your pharmacist who will advise you.

At a glance

  • Cabergoline is a medicine used to treat conditions caused by high prolactin levels and Parkinson's disease.

  • It prevents prolactin production and encourages dopamine release.

  • Your doctor will tell you how much to take and how often.

  • Take tablets with a meal to help reduce feeling sick.

  • Cabergoline can cause side effects like tiredness, dizziness, and sudden sleepiness.

  • Seek medical advice if you experience breathlessness, chest pain, or changes in behaviour.

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About cabergoline

Tipo de medicamento

Um medicamento dopaminérgico

Usado para

Disorders due to high prolactin levels; Parkinson's disease

Também chamado de

Dostinex® (for high prolactin levels)

Cabaser® (for Parkinson's disease)

Disponível como

Comprimidos

Cabergoline is prescribed for a number of different medical conditions. Your doctor will tell you why it has been prescribed for you.

  • Cabergoline prevents the production of a chemical called prolactin. Prolactin is involved in a number of processes within the body, including milk production after childbirth. Cabergoline is therefore helpful in preventing or reducing milk production when this is needed for medical reasons.

  • High levels of prolactin occur in people with prolactinomas. A prolactinoma is a non-cancerous swelling in the pituitary gland. This can cause various symptoms including reduced fertility, breast changes, and headaches. Prolactinomas can be treated successfully with medicines which reduce the production of prolactin, such as cabergoline. In these cases, treatment is usually long-term.

  • Cabergoline can be prescribed to treat Doença de Parkinson, although other treatments are usually preferred. In Parkinson's disease, a number of cells in a small part of the brain become damaged and die. These brain cells normally pass messages down nerves in the spinal cord by producing a chemical called dopamine, and it is these messages which control the muscles of the body. As the cells are damaged, the amount of dopamine that is produced is reduced. A combination of the reduction of cells and a low level of dopamine in the cells in this part of the brain, causes nerve messages to the muscles to become slowed and abnormal. This produces the main symptoms of Parkinson's disease, which are stiffness, shaking (tremor), and slowness of movement. Cabergoline encourages the release of dopamine which helps to ease these symptoms.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking cabergoline it is important that your doctor knows:

  • Se você está grávida ou amamentando.

  • If you have been told you have scar tissue affecting your heart, lungs or abdomen.

  • Se você tem uma condição cardíaca ou doença dos vasos sanguíneos.

  • Se você já teve uma úlcera estomacal.

  • Se você tem um problema com o funcionamento do seu fígado.

  • Se você tem um problema de circulação chamado síndrome de Raynaud.

  • Se você já teve um problema sério de saúde mental, como um transtorno psicótico.

  • Se você tem um distúrbio sanguíneo hereditário raro chamado porfiria.

  • Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

  • Se você já teve uma reação alérgica a um medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cabergoline and will provide you with a full list of the side-effects which you may experience from taking it.

  • The dose you will need to take will depend upon the reason you are taking cabergoline. You may be asked to take cabergoline just for a few days if it is to stop breast milk; or each day if you have Parkinson's disease; or, if you are taking cabergoline to reduce high prolactin levels, you may only need one dose a week. Your doctor will tell you how much to take and how often to take it, and this information will also be printed on the label of the pack to remind you.

  • Read the directions from your doctor carefully and take cabergoline exactly as you are told to. If you are taking cabergoline for the first time, your doctor may give you a small dose and then gradually increase your dose. Slowly increasing your dose like this will help to reduce side-effects, such as dizziness, which can occur during the first few days of treatment.

  • Swallow the tablet with a drink of water, at a mealtime. Taking cabergoline with a meal will help to reduce the risk of feeling sick (nausea).

  • Try to take cabergoline at the same time(s) of day each day; if you are taking it weekly, take it on the same day of the week each week.

  • Se você esquecer de tomar uma dose, tome-a assim que se lembrar. Se, ao se lembrar, já estiver quase na hora da próxima dose, tome a próxima dose no horário habitual, mas pule a dose esquecida. Não tome duas doses juntas para compensar uma dose esquecida.

  • Try to keep your regular appointments with your doctor so your progress can be checked. Cabergoline can cause heart and lung problems, particularly in people who need to take it over a long period of time. In order for your doctor to check for this, you may need to have an ECG, lung function tests, blood tests and an X-ray from time to time if you are taking cabergoline long-term.

  • There are two different brands and several different strengths of cabergoline tablets. Each time you collect a fresh supply of tablets, it's a good idea to check the packet to make sure they are what you are expecting. If you have any questions about your tablets, ask your pharmacist for advice.

  • If you are a woman, you may want to discuss what forms of contraception are suitable for you. Hormonal forms of contraception (such as 'the pill') may not be suitable while you are taking cabergoline. You should avoid becoming pregnant during treatment with cabergoline and for one month after stopping.

  • Sometimes people taking cabergoline can fall asleep suddenly with little or no warning of being tired beforehand. Until you know how you react, take extra care if you drive and if you operate machinery. If you do find yourself falling asleep suddenly, you should see your doctor as soon as possible for advice. Avoid driving and avoid use of tools and machines in the meantime.

  • Treatment with medicines like cabergoline can sometimes cause problems with impulsive types of behaviour. If you notice any changes in your behaviour, such as an increased desire to gamble, binge eat, or spend excessively, or an increased sex drive, you must let your doctor know as soon as possible.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cabergoline. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common cabergoline side-effects

O que posso fazer se passar por isso?

Feeling tired, sleepy or dizzy

Se isso acontecer, não dirija e não use ferramentas ou máquinas até se sentir melhor

Dor de cabeça

Se a dor de cabeça for intensa ou persistir, fale com seu médico imediatamente; caso contrário, peça ao seu farmacêutico para recomendar um analgésico adequado

Sentindo-se mal (náusea) ou vomitando, indigestão

Stick to simple meals - avoid rich or spicy foods. Remember to take the tablets after food

Constipação

Tente manter uma dieta equilibrada e beba bastante água todos os dias

Disturbed sleep, swollen hands or feet

Se algum desses se tornar problemático, fale com seu médico

Changes in the way you feel (such as being depressed or confused), thinking things that are not true (hallucinations), uncontrollable muscle movements

You should let your doctor know about these as soon as possible

Alterações em alguns resultados de exames de sangue

Seu médico verificará estes

Importante: cabergoline can cause some more serious side-effects. It is important that you contact your doctor for advice imediatamente if you develop any of the following:

  • Qualquer falta de ar ou dificuldades para respirar, ou uma tosse que não passa.

  • Dor ou desconforto no peito ou no abdômen (barriga).

If you experience any other symptoms which you think may be due to cabergoline, speak with your doctor or pharmacist for further advice.

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Keep the tablets in their original container - it contains a silica gel desiccant to protect the tablets from the moisture in the air. Do not swallow the desiccant.

  • Store the container in a cool, dry place, away from direct heat and light.

Informações importantes sobre todos os medicamentos

Se você estiver prestes a fazer uma operação ou tratamento dentário, informe à pessoa que realizará o tratamento quais medicamentos você está tomando.

Se você tomar qualquer medicamento que comprou sem receita, verifique com um farmacêutico se eles são adequados para tomar junto com seus medicamentos prescritos.

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

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Relate efeitos colaterais suspeitos de medicamentos, vacinas, cigarros eletrônicos, incidentes com dispositivos médicos, produtos defeituosos ou falsificados (falsos) à Agência Reguladora de Medicamentos e Produtos de Saúde para garantir o uso seguro e eficaz.

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Perguntas frequentes

Why is cabergoline used for different conditions, like high prolactin levels and Parkinson's disease, if they seem unrelated?

Cabergoline works by affecting different chemical processes in the body. For high prolactin levels, it stops the production of prolactin. For Parkinson's disease, it encourages the release of dopamine, which helps to ease the symptoms of stiffness, shaking, and slowness of movement.

What specifically should I tell my doctor before starting cabergoline regarding existing health conditions?

Before starting cabergoline, it's important to tell your doctor if you are pregnant or breastfeeding, have scar tissue affecting your heart, lungs, or abdomen, a heart condition, blood vessel disease, a stomach ulcer, liver problems, Raynaud's syndrome, a serious mental health problem (like a psychotic disorder), or a rare blood disorder called porphyria. Also, mention all other medicines you are taking, including non-prescription, herbal, or complementary ones, and if you've ever had an allergic reaction to any medicine.

How long will I need to take cabergoline for?

The duration of your treatment will depend on why you are taking cabergoline. If it's to stop breast milk production, you might only take it for a few days. If it's for Parkinson's disease, you will likely take it daily. For high prolactin levels, treatment is usually long-term, and you might only need one dose a week.

Are there any specific lifestyle adjustments I should make while taking cabergoline?

Yes, there are a few. Always take cabergoline with a meal to reduce the risk of feeling sick. If you experience sudden sleepiness, avoid driving or operating machinery and contact your doctor. If you notice changes in your behaviour like increased gambling, binge eating, excessive spending, or an increased sex drive, inform your doctor immediately. If you are a woman of childbearing potential, discuss suitable contraception as hormonal methods may not be suitable, and you should avoid pregnancy during and for one month after treatment.

What measures are taken to monitor for serious side-effects of cabergoline, especially during long-term use?

If you are taking cabergoline long-term, your doctor will schedule regular appointments to check your progress. This may include having an ECG, lung function tests, blood tests, and an X-ray from time to time to monitor for potential heart and lung problems that can occur with long-term use.

I'm concerned about 'impulsive types of behaviour' mentioned as a side-effect. What exactly does this mean and what should I look out for?

Impulsive types of behaviour can include an increased desire to gamble, binge eat, or spend excessively, as well as an increased sex drive. It's important to be aware of these potential changes. If you notice any of these behaviours developing or becoming more prominent, you must let your doctor know as soon as possible.

What should I do if I forget to take a dose of cabergoline?

If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses together to try and make up for the forgotten one.

Leitura adicional e referências

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão prevista para: 30 Nov 2026
  • 1 Dez 2023 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
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