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Acetato de ciproterona - um antiandrogênico para homens

Cyprostat, Androcur

Take cyproterone tablets with a drink of water and something to eat.

Cyproterone may make you feel tired or weak. If this happens, do not drive and do not use tools or machines.

Cyproterone can affect the way your liver works and the way your adrenal glands work. Your doctor will discuss the risk of these with you before you start the treatment.

Em resumo

  • Cyproterone is an anti-androgen medicine.

  • It is used to treat prostate cancer in men and to control hypersexuality in men.

  • Take cyproterone with food or a snack.

  • Cyproterone can make you feel tired, so do not drive or use machines if this happens.

  • Your doctor will monitor your liver and adrenal gland function with blood tests.

  • Tell your doctor if you experience yellow skin/eyes, stomach pain, or feel very tired or depressed.

About cyproterone

Tipo de medicamento

Anti-androgen

Usado para

To treat prostate cancer in men; to control hypersexuality in men

Também chamado de

Cyprostat® (used for prostate cancer); Androcur® (used for hypersexuality)

Disponível como

Comprimidos

Cyproterone belongs to a group of medicines known as anti-androgens. This means that it blocks the actions of male sex hormones called androgens, and it also reduces the amount of male hormones your body produces. This anti-androgen action can be helpful in the treatment of two different conditions - in the treatment of câncer de próstata, and to control the sex drive in men with hypersexuality.

In prostate cancer, the cancer cells need the male hormone testosterone to grow and multiply well. Hormone treatments like cyproterone block the effect of testosterone on prostate cancer cells. This slows down the growth of the cancer. Cyproterone also helps to reduce symptom 'flares' and side-effects from other treatments which may be used for the cancer, or following surgery.

In men who have hypersexuality, cyproterone is used to control sexual desire or deviation. If you are prescribed cyproterone for this reason, your doctor will ask you to sign an agreement before you start the treatment.

Cyproterone is also found in very low doses in a contraceptive tablet called co-cyprindiol. It is useful for managing cicatrizes de acne or excess hair growth (hirsutism) whilst also providing contraception.

Before taking cyproterone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking cyproterone it is important that your doctor knows:

  • If you are under 18 years old. Cyproterone is not recommended for this age group.

  • If you are depressed.

  • If you have any problems with the way your liver works, or if you drink a lot of alcohol.

  • Se você tem diabetes.

  • If you have blood vessel problems, such as if you have ever had a blood clot in a leg or lung.

  • If you have a type of anaemia known as sickle cell anaemia.

  • If you have ever had a type of brain tumour called meningioma, or if you have been diagnosed with another type of cancer (other than prostate cancer if that is what you are being treated for).

  • Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

  • Se você já teve uma reação alérgica a um medicamento.

How to take cyproterone

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cyproterone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take cyproterone exactly as your doctor tells you to. How you should take the tablets will depend on what condition you are being treated for, so your doctor will give you full directions. Your dose will also be printed on the label of the pack to remind you about what the doctor said to you.

  • Take your doses with a snack, or just after eating a meal. Swallow the tablets with a drink of water.

  • Try to take cyproterone at the same times of day each day. This will help you to remember to take your doses regularly.

  • If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.

Obtendo o máximo do seu tratamento

  • Please keep your regular appointments with your doctor. Your doctor will want you to have some blood tests both before and during your treatment. The tests will check the levels of your blood cells, and that your liver stays healthy. Your doctor will also want to check that your adrenal glands are not being affected by the treatment.

  • Cyproterone can make you feel tired or weak. If this happens to you, do not drive and do not use tools or machines, as these symptoms may put others as well as yourself at risk.

  • Your doctor may recommend you do not drink alcohol while you are on cyproterone. This is because regularly drinking alcohol can stop cyproterone from working as well as it should.

  • When you have been taking cyproterone for some weeks, your sperm count will reduce and you are likely to become unable to father a child. You must not, however, rely on cyproterone as a contraceptive. Although this infertility is likely to reverse when you stop taking cyproterone, you should speak with your doctor if you are thinking of having children in the future.

Can cyproterone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cyproterone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common cyproterone side-effects


O que posso fazer se passar por isso?

Reduced sperm count

Your doctor will discuss this with you before your treatment starts

Feeling tired or weary

Se isso acontecer, não dirija e não use ferramentas ou máquinas

Hot flushes and sweating

Try to keep yourself cool by wearing light and airy clothes

Changes in your weight, feeling depressed or restless, breast tenderness, feeling short of breath

Se algum desses se tornar problemático, fale com seu médico

Importante: cyproterone can affect the way your liver works and the way your adrenal glands work. Your doctor will discuss this with your before you start the treatment, but it is important you tell your doctor if you develop any of the following:

  • Any yellowing of your skin or of the whites of your eyes, or if you develop any stomach discomfort or pain that does not go away quickly. These can be signs that your liver is being affected.

  • If you feel very tired, start losing your appetite or weight, develop diarrhoea or sickness (vomiting), or feel particularly irritable or depressed. These can be signs that your adrenal glands are being affected.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, por favor, fale com seu médico ou farmacêutico para mais orientações.

How to store cyproterone

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

Este medicamento é para você. Não o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Se você estiver prestes a fazer uma operação ou tratamento dentário, por favor, informe à pessoa que realizará o tratamento quais medicamentos você está tomando.

Se você comprar qualquer medicamento, verifique com um farmacêutico se eles são adequados para tomar com seus outros medicamentos.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

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Inseguro sobre misturar medicamentos?

Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.

Perguntas frequentes

What is the age restriction for taking cyproterone?

Cyproterone is not recommended for individuals who are under 18 years old. Your doctor will need to know if you are in this age group before prescribing the medication.

Can cyproterone affect my ability to have children in the future?

Yes, after taking cyproterone for some weeks, your sperm count will reduce, and you will likely become unable to father a child. While this infertility is likely to reverse if you stop taking cyproterone, it's important to discuss your plans for having children with your doctor if this is a concern for you.

What should I do if I become depressed while taking cyproterone?

If you experience changes in your mood, such as feeling depressed, and these become troublesome, you should speak with your doctor for advice. Depression is listed as a possible side-effect that needs medical attention if it persists or worsens.

What are the early warning signs of liver or adrenal gland problems while on cyproterone?

You should tell your doctor immediately if you notice any yellowing of your skin or eyes, or if you have stomach discomfort or pain that doesn't go away quickly, as these can signal liver issues. For adrenal gland problems, watch out for feeling very tired, losing appetite or weight, developing diarrhoea or sickness (vomiting), or feeling particularly irritable or depressed.

Leitura adicional e referências

Sobre o autorVer biografia completa

Imagem do autor

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

Sobre o revisor

Imagem do autor

Sid Dajani

Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão prevista para: 13 Jun 2027
  • 10 Jun 2024 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
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