Diltiazem
AdizemTildiem, Zemtard
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSLast updated 9 Jan 2023
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When you first start taking diltiazem you may get a headache, feel flushed, or get swollen ankles. These symptoms usually pass after a few days.
Each time you collect a new supply of diltiazem, check to make sure you have been given the same type of tablets or capsules as before.
At a glance
Diltiazem is a medicine used to treat high blood pressure and prevent angina.
It works by relaxing blood vessels and reducing the heart's force and rate.
Take your tablets or capsules exactly as your doctor tells you, usually once or twice a day.
Common side-effects include headaches, dizziness, and swollen ankles which often improve.
Do not suddenly stop taking diltiazem without discussing it with your doctor.
If you experience new chest pain or worsening angina, contact your doctor.
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About diltiazem
Tipo de medicamento | Calcium-channel blocker |
Usado para | High blood pressure, and angina |
Também chamado de | Adizem®; Angitil®; Dilcardia®; Retalzem®; Slozem®, Tildiem®; Viazem®; Uard®; Zemtard® |
Disponível como | Comprimidos e cápsulas |
Diltiazem is used to treat pressão alta (hipertensão) and prevent chest pain caused by angina. It works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina pain.
Before taking diltiazem
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking diltiazem it is important that your doctor knows:
Se você está grávida, tentando ter um bebê ou amamentando.
If you have any problems with your kidneys or liver.
If you have a heart condition (such as heart failure, an abnormal heart rhythm, or if you have had a heart attack recently).
Se você tem níveis elevados de açúcar no sangue (diabetes mellitus).
If you have asthma or other breathing problems.
Se você tem um distúrbio sanguíneo hereditário raro chamado porfiria.
Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
If you have ever had an allergic reaction to this or to any other medicine.
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How to take diltiazem
Voltar ao conteúdoBefore you start taking diltiazem, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about the specific brand of tablet or capsule you have been given, and a full list of side-effects which you may experience from taking it.
There are several different formulations of diltiazem available, so it is important that you take your tablets or capsules exactly as your doctor tells you to. 'Standard' 60 mg tablets are taken three times daily, whereas longer-acting tablets or capsules are taken once a day or twice a day. Your doctor will tell you which is right for you, and this will also be printed on the label of the pack to remind you.
Try to take diltiazem at the same times each day, as this will help you to remember to take your doses.
Swallow the tablets or capsules whole with a drink of water - do not chew, break or crush them. You can take diltiazem before or after food.
Se você esquecer de tomar uma dose, tome-a assim que se lembrar, a menos que esteja quase na hora da próxima dose, nesse caso, pule a dose esquecida. Não tome duas doses juntas para compensar uma dose esquecida.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoTente manter suas consultas regulares com seu médico. Isso é para que seu médico possa verificar seu progresso.
Your doctor will discuss with you the possibility of unwanted side-effects when you first start taking diltiazem. You may experience headaches, feeling flushed, swollen ankles and some dizziness. These effects usually only last for a few days, but if they continue or become troublesome, you should let your doctor know.
Different formulations and brands of diltiazem can act in a slightly different way in your body. Because of this, it is important that you continue to take the same type of tablet or capsule as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same and that the brand name is the same. If you are unsure, or if have any questions about your prescription, please ask your pharmacist to check it for you.
If you have diabetes you may need to check your blood sugar (glucose) level more often. This is because diltiazem may raise your glucose levels. Ask your doctor or pharmacist for advice.
Before you buy any medicines or take any 'over-the-counter' remedies, please check with a pharmacist that they are suitable for you to take. This is because some medicines can interact with diltiazem.
Drinking grapefruit juice may affect the amount of diltiazem in your blood and can make you more likely to experience side-effects. Let your doctor or pharmacist know if you enjoy drinking grapefruit juice and wish to continue.
If you need to have an operation or any medical treatment, always tell the person carrying out the treatment which medicines you are taking. Diltiazem may interfere with the way some anaesthetics work.
If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine as it may increase the chance that you experience side-effects, such as feeling dizzy or light-headed.
Suddenly stopping treatment may cause problems, so keep taking diltiazem unless your doctor tells you otherwise. If it does become necessary for you to stop treatment, your doctor will want you to reduce your dose over a few days.
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Can diltiazem cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diltiazem. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common diltiazem side-effects | O que posso fazer se passar por isso? |
Feeling dizzy or light-headed, especially when sitting or standing up | Getting up more slowly may help. Do not drive and do not use tools or machines until you feel better |
Dor de cabeça | Beba bastante água e peça ao seu farmacêutico que recomende um analgésico adequado. Se as dores de cabeça continuarem, fale com o seu médico |
Indigestion, feeling sick (nausea) | Prefira refeições simples - evite alimentos ricos e condimentados |
Constipação | Tente manter uma dieta equilibrada e beba vários copos de água todos os dias |
Red or itchy skin | Ask a pharmacist to recommend a suitable remedy. If it becomes troublesome, let your doctor know |
Swollen ankles, feeling hot and flushed, being aware of your heartbeat, feeling tired | Speak with your doctor about these if any continue beyond a few days or become troublesome |
Importante: if you get chest pain, or if your angina pain gets worse or becomes more frequent, contact your doctor as soon as possible.
Se você sentir quaisquer outros sintomas que acha que podem ser devido a este medicamento, fale com seu médico ou farmacêutico.
How to store diltiazem
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Yellow Card website.

Inseguro sobre misturar medicamentos?
Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.
Perguntas frequentes
Can I switch between different brands or types of diltiazem if they are both 60 mg tablets?
No, it's important to stick to the same type and brand of tablet or capsule you've been prescribed each time. Different versions of diltiazem can work slightly differently in your body. Always check to make sure your new supply looks the same and has the same brand name. If you have any questions, ask your pharmacist.
I have diabetes. Do I need to be aware of anything specific when taking diltiazem?
Yes, if you have diabetes, you might need to check your blood sugar (glucose) levels more frequently. Diltiazem has the potential to raise your glucose levels. It's best to discuss this with your doctor or pharmacist for personalised advice.
What should I do if I feel dizzy or light-headed shortly after starting diltiazem?
Feeling dizzy or light-headed, especially when sitting or standing up, is a common side-effect that usually improves within a few days. Getting up more slowly can help. You should avoid driving or operating machinery until you feel better. If these effects continue or become troublesome, let your doctor know.
Can I drink alcohol while taking diltiazem?
It is advisable to discuss alcohol consumption with your doctor. They might recommend that you avoid alcohol while on this medication, as it could increase your chances of experiencing side-effects like dizziness or light-headedness.
Do I need to inform healthcare providers about my diltiazem medication if I'm having surgery or other medical treatment?
Yes, it is very important to tell anyone carrying out an operation or any medical treatment that you are taking diltiazem. This is because diltiazem can affect how some anaesthetics work.
What should I do if my angina pain gets worse or I start experiencing it more often while taking diltiazem?
If you experience new chest pain, or if your existing angina pain worsens or becomes more frequent, you should contact your doctor as soon as possible. This is an important symptom to report immediately.
Leitura adicional e referências
- Manufacturer's PIL, Tildiem® 60 mg Modified-Release Tablets; Sanofi Ltd, The electronic Medicines Compendium. Dated August 2021.
- Manufacturer's PIL, Adizem®-SR 90 mg, 120 mg and 180 mg prolonged-release capsules; Napp Pharmaceuticals Limited, The electronic Medicines Compendium. Dated November 2020.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
- Manufacturer's PIL, Adizem®-XL 120 mg, 180 mg, 200 mg, 240 mg and 300 mg prolonged release capsules; Napp Pharmaceuticals Limited, The electronic Medicines Compendium. Dated November 2020.
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About the authorView full bio

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 8 Jul 2027
9 Jan 2023 | Última versão

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