Memantina para demência
Ebixa, Valios
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 19 Jan 2025
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Memantine helps to ease the symptoms of dementia in Alzheimer's disease.
Take one dose every day, at the same time of day each day. You can take memantine either before or after meals.
You will be given a small dose when you first start treatment. This will gradually be increased over the following few weeks.
Em resumo
Memantine is a medicine for moderate or severe Alzheimer's disease.
It helps with thinking symptoms like memory loss and confusion.
It is not a cure but can slow symptom progression.
Specialists prescribe it, especially if other Alzheimer's medicines are unsuitable.
A caregiver must supervise the treatment.
Take your dose regularly, at the same time each day.
Não dirija ou opere máquinas se sentir tontura ou sono.
About memantine
Tipo de medicamento | An anti-dementia medicine (a glutamate receptor antagonist) |
Usado para | Symptoms of dementia in Alzheimer's disease |
Também chamado de | Ebixa®, Valios® |
Disponível como | Tablets, soluble tablets, melt-in-the-mouth (orodispersible) tablets and oral liquid medicine |
Memantine is prescribed for people who have dementia which is associated with Alzheimer's disease. It is used to help the symptoms which affect thinking, such as memory loss and confusion. You can find out more about medicines like memantine in the separate leaflet called Medicines for dementia.
Memantine is not a cure, but it can slow down the progression of the symptoms in some people. It works by reducing the amount of a brain chemical called glutamate. It is thought that this may help to slow down the damage to brain cells affected by Alzheimer's disease.
Memantine will be prescribed by a specialist doctor. It is prescribed for people with moderate or severe Alzheimer's disease, who for some reason cannot take the other medicines more usually prescribed for Alzheimer's disease. It will only be started for people who have a caregiver able to supervise the treatment. If you are the caregiver, please read this document on behalf of the person who is receiving memantine.
Before taking memantine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking memantine it is important that your doctor knows:
Se você tiver algum problema com o funcionamento dos seus rins, ou qualquer problema com o funcionamento do seu fígado.
If you have ever had fits.
Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
Se você já teve uma reação alérgica a um medicamento.
How to take memantine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about memantine and will provide you with a full list of the side-effects which you could experience from taking it.
Your caregiver will help you take your tablets/medicine exactly as your doctor tells you to. Take one dose every day.
Your doctor will start you on a dose of 5 mg and then gradually increase your dose over the following few weeks. This allows your doctor to make sure that you have the dose that helps your condition but avoids any unwanted symptoms.
You can take memantine at whatever time of day you find easiest to remember, but try to take your doses at the same time of day each day. It can be taken either with or without food.
Doses of the oral liquid medicine must be measured using the dose pump which is supplied with the bottle. When you first open a bottle, attach the pump to the bottle and 'prime' it by pushing the head of the pump down five times. Throw away any solution that comes out of the bottle as you do this. The next time you use the pump, it will provide a dose of 5 mg every time you push it down fully. Measure out the correct dose on to a spoon or into a glass of water. If you are at all unsure of what to do or how to use the pump to measure out the correct dose, ask your pharmacist to show you.
If you have been given soluble tablets, dissolve the tablet in half a glass of water and drink it straightaway. Alternatively, soluble tablets can be swallowed whole with a drink of water.
If you have been given melt-in-the-mouth (orodispersible tablets), place the tablet on your tongue and allow it to dissolve before swallowing. Handle the tablets as little as possible and do not touch them with wet hands as they will start to dissolve.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Obtendo o máximo do seu tratamento
It may take several weeks before memantine appears to take effect. Continue to take your doses every day until you are told otherwise by your doctor.
Your doctor will want to check your progress every few weeks to make sure that the dose is right for you and that you are getting benefit from the treatment. Always try to keep these regular doctor's appointments.
There are several strengths of memantine tablet available - 5 mg, 10 mg, 15 mg, and 20 mg. Each time you collect a fresh supply, check the label on the box to make sure it is the strength of tablet you are expecting.
If you make any major changes to your diet, please let your doctor know. This is because your dose may need adjusting if, for example, you change from a diet that includes meat, to one that contains only vegetables.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking memantine. This is particularly important if you are going to need a general anaesthetic.
Can memantine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with memantine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common memantine side-effects (these affect fewer than 1 in 10 people) | O que posso fazer se passar por isso? |
Constipação | Tente manter uma dieta equilibrada e beba vários copos de água todos os dias |
Dor de cabeça | Beba bastante água e peça ao seu farmacêutico para recomendar um analgésico adequado. Se as dores de cabeça continuarem, informe o seu médico |
Feeling sleepy or dizzy, difficulties with balance | Take care as you move about. Do not drive and do not use tools or machines |
Feeling short of breath, allergic reactions | Informe seu médico sobre isso |
High blood pressure, changes in your liver function tests | Your doctor will monitor you for these |
Se você sentir quaisquer outros sintomas que acha que podem ser devido ao medicamento, por favor, fale com seu médico ou farmacêutico para mais orientações.
How to store memantine
Mantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Once opened, a bottle of the medicine only keeps for three months. Do not store it or use it after this time.
Informações importantes sobre todos os medicamentos
Informações importantes sobre todos os medicamentos
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Se você comprar qualquer medicamento, sempre verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

Inseguro sobre misturar medicamentos?
Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.
Perguntas frequentes
What is memantine for?
Memantine is prescribed for people with moderate or severe Alzheimer's disease to help manage symptoms affecting thinking, such as memory loss and confusion. It is used when other more commonly prescribed medicines for Alzheimer's are not suitable.
Can I take memantine if I have kidney or liver problems?
If you have any problems with how your kidneys or liver work, it's important to let your doctor know before starting memantine. Your doctor will need to consider these conditions to ensure it is safe for you to take.
What should I do if I forget to take a dose of memantine?
If you forget a dose, take it as soon as you remember. However, if you don't remember until the following day, you should skip the missed dose. Do not take two doses at once to make up for a forgotten dose.
How long does it take for memantine to start working?
It may take several weeks before you notice the effects of memantine. It's important to continue taking your doses daily as prescribed by your doctor.
Can diet changes affect my memantine dosage?
Yes, if you make any significant changes to your diet, such as switching from a meat-inclusive diet to a purely vegetarian one, you should inform your doctor. Your memantine dose may need to be adjusted.
What should I do if I experience drowsiness or dizziness from memantine?
If you feel sleepy or dizzy, or have difficulties with balance, take extra care when moving around. You should not drive or operate tools or machines if you are experiencing these side-effects. If they continue or become bothersome, speak with your doctor or pharmacist.
How should I store the oral liquid form of memantine?
Keep the oral liquid medicine in a cool, dry place, away from direct heat and light, and out of reach of children. Once a bottle has been opened, it should only be used for three months. Do not store or use it after this time.
Leitura adicional e referências
- Manufacturer's PIL, Ebixa® 5 mg, 10 mg, 15 mg and 20 mg Film-Coated Tablets; Lundbeck Limited, The electronic Medicines Compendium. Dated July 2021.
- Manufacturer's PIL, Ebixa® 5 mg/pump actuation oral solution; Lundbeck Limited, The electronic Medicines Compendium. Dated July 2021.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
Sobre o autorVer biografia completa

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
Sobre o revisor

Sid Dajani
Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Artigo também disponível em Inglês, Alemão, Espanhol, Francês, Italiano, Português, Hindi, Hebraico, Árabe, e Sueco.
Próxima revisão prevista: 19 Jan 2028
19 Jan 2025 | Última versão

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