Buserelin for men
Suprefact
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 14 Sept 2024
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Buserelin (brand name Suprefact®) is a hormone treatment for men with prostate cancer who have not had surgery to remove the testicles.
Each time you collect your prescription for buserelin, check to make sure the brand name is Suprefact®. This is because there is another brand of buserelin nasal spray available, which is not suitable for you.
Use one spray into each nostril six times each day.
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About buserelin for men
Tipo de medicamento | A gonadorelin analogue |
Usado para | Câncer de próstata |
Também chamado de | Suprefact® |
Disponível como | Injection and nasal spray |
Although in many cases câncer de próstata is slow-growing, in some men it can be more aggressive and spread to other parts of the body. When this happens, there can be a benefit from using a hormone treatment, such as buserelin, which slows the progress of the cancer.
Prostate cancer cells need the male hormone testosterone to grow. Buserelin works by reducing the production of testosterone and this helps to stop the growth of the cancer cells.
Buserelin is also used in some disorders which affect women. There is a separate medicine leaflet called Buserelin for women que fornece mais informações sobre isso.
Before using buserelin
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using buserelin it is important that your doctor knows:
If you have low moods or are depressed.
Se você tem pressão alta (hipertensão).
If you have diabetes (diabetes mellitus).
If you have a bone disease such as osteoporosis.
Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.
Se você já teve uma reação alérgica a um medicamento.
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How to use buserelin
Voltar ao conteúdoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about buserelin and will provide you with a full list of the side-effects which you could experience.
When you start buserelin, you will be given injections every eight hours for the first seven days. For convenience, these injections are likely to be given to you while you are in hospital. On the next day, you will be given a nasal spray to use. You must follow the instructions given to you by your doctor for using the spray, but it is usually recommended that you use one spray into each nostril six times each day as follows:
1st dose before your breakfast.
2nd dose after your breakfast.
3rd dose before your midday meal.
4th dose after your midday meal.
5th dose before your evening meal.
6th dose after your evening meal.
Each time you open a new bottle, you will need to attach the nebuliser to the bottle of solution and then 'prime' the spray. You do this by pumping the spray about six or seven times until you see a fine spray produced. Priming fills the nebuliser and tests that the spray is working correctly.
It is important that you use this medicine regularly and space the doses out evenly through the day. If you forget to take a dose at your usual time, take it as soon as you remember. If it is almost time for your next dose then skip the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
About 1 in 10 men notice that their symptoms (usually pain) become worse for a short while when they first start treatment with buserelin. Your doctor is likely to give you some tablets to take during the first few weeks to help prevent this. If you do experience any increase in pain, this will settle again after a couple of weeks.
Please keep your appointments with your doctor so that your progress can be monitored. Your doctor will want you to have regular blood tests to check your hormone levels.
Even if you get a cold or your nose feels blocked, you should continue to use the spray as it will still work. If you are using any other nasal sprays (such as decongestants), you should use buserelin spray first, then wait at least 30 minutes after using buserelin before using the other nasal spray.
Buserelin can affect your blood sugar levels. If you have diabetes you may need to check your blood glucose more frequently. Your doctor will advise you about this.
Can buserelin cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with buserelin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common buserelin side-effects (these affect fewer than 1 in 10 men) | O que posso fazer se passar por isso? |
Feeling dizzy, tired, or sleepy | If this happens, do not drive and do not use tools or machines while affected |
Feeling sick (nausea) or being sick (vomiting), stomach or tummy (abdominal) pain | Mantenha-se em alimentos simples - evite refeições ricas ou picantes |
Diarreia | Beba bastante água para repor os líquidos perdidos |
Constipação | Eat a well-balanced diet and drink several glasses of water each day |
Headache, muscle pain and stiffness | Peça ao seu farmacêutico para recomendar um analgésico adequado |
Irritation of your nose or throat, nosebleeds, changes in the way things smell and taste, changes in your weight, feeling nervous or depressed, disturbed sleep, being aware of a fast heartbeat, dry skin, acne, changes in the thickness of your hair | Se algum desses se tornar problemático, fale com seu médico |
Importante: In rare cases this medicine may cause a serious allergic reaction. Seek urgent medical attention if you develop a red, itchy skin rash and any difficulties with your breathing, including swelling of the face, lips or tongue. Taking an antihistamine may help slow the reaction whilst you are waiting for treatment.
If you experience any other symptoms which you think may be due to buserelin, please speak with your doctor or pharmacist for further advice.
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How to store buserelin
Voltar ao conteúdoMantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Each bottle of nasal spray contains one week of treatment. Even if there is some solution left after using the spray for a week, please do not use it. Instead, open a fresh bottle.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Se você comprar qualquer medicamento, verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do site Cartão Amarelo.
Vídeos selecionados para Tratamento e medicamentos para o câncer

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Leitura adicional e referências
- Manufacturer’s PIL, Suprefact® 100 micrograms Nasal Spray Solution; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated October 2020.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Next review due: 3 Sept 2027
14 Sept 2024 | Última versão

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