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Valsartan - an angiotensin receptor blocker

You can take valsartan either before or after a meal.

Any side-effects are usually mild. The most common side-effect is dizziness.

Some painkillers may interfere with valsartan and increase the risk of side-effects, so ask a pharmacist for advice before you buy any medicines.

Clinical author's note: Michael Stewart 15/11/2018:Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as valsartan. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the Alerta MHRA.

At a glance

  • Valsartan is a medicine used to treat high blood pressure, heart failure, and protect the heart.

  • It works by relaxing and widening blood vessels, which lowers blood pressure and helps the heart.

  • Take valsartan exactly as prescribed, usually once or twice a day, with or without food.

  • Common side-effects can include feeling tired or dizzy.

  • Tell your doctor if you have kidney or liver problems, or are pregnant or breastfeeding.

  • Seek medical help immediately for swelling of your face or mouth after taking it.

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About valsartan

Tipo de medicamento

Um antagonista do receptor de angiotensina II

Usado para

Hypertension; heart failure; to protect the heart

Também chamado de

Diovan®;
Combination brands: Co-Diovan® (valsartan with hydrochlorothiazide); Exforge® (valsartan with amlodipina); Entresto® (valsartan with sacubitril)

Disponível como

Comprimidos, cápsulas e medicamentos líquidos orais

Valsartan is an angiotensin receptor blocker. It is also called an angiotensin-II receptor antagonist, or an AIIRA. You will have been prescribed valsartan either because your pressão arterial muito alta (hipertensão), or because your heart is not working as well as it should (insuficiência cardíaca), or to protect your heart if you have recently had a heart attack.

Valsartan works by blocking the effect of a chemical called angiotensin II. Angiotensin II causes your blood vessels to narrow, so by blocking its effect valsartan allows your blood vessels to relax and widen. As this happens, the pressure within your blood vessels is reduced and it is easier for your heart to pump blood around your body. Valsartan also helps to protect the heart following a heart attack.

Valsartan may be prescribed on its own to treat high blood pressure, or you may also be given other medicines to take alongside it. This is because a combination of medicines which work in different ways can often lower your blood pressure more than one medicine on its own. Combination brands which contain valsartan alongside other medicines for high blood pressure include Co-Diovan® and Exforge®. Being prescribed a combination brand like these will help to reduce the number of tablets you need to take each day.

One combination brand, called Entresto®, is prescribed for heart failure and contains valsartan with sacubitril.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking valsartan it is important that your doctor knows:

  • Se você está grávida, tentando ter um bebê ou amamentando.

  • If you have a problem with your kidneys, particularly if it is a blockage of the artery which supplies blood to your kidneys.

  • Se você tiver algum problema com suas válvulas cardíacas ou músculo cardíaco.

  • If you have a problem with the way your liver works, or if you have a condition which blocks the flow of bile from your liver.

  • Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

  • Se você já teve uma reação alérgica a um medicamento.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about valsartan and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take valsartan exactly as your doctor tells you to. You may be asked to take valsartan once or twice a day depending on the reason why you are taking it. When you first start treatment, your doctor may gradually increase the strength of your dose to suit your condition. There are several different strengths of tablet/capsule available, so each time you collect a fresh supply, it's a good idea to check the strength on the packet to make sure they are what you are expecting.

  • Try to take valsartan at the same time(s) of day each day. Taking your doses at the same times will help you to remember to take valsartan regularly.

  • Swallow the tablet/capsule with a drink of water. You can take valsartan either before or after a meal.

  • Se você esquecer de tomar uma dose, tome-a assim que se lembrar. Se, ao se lembrar, já estiver quase na hora da próxima dose, tome a próxima dose no horário habitual, mas pule a dose esquecida. Não tome duas doses juntas para compensar uma dose esquecida.

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored and your blood pressure measured. Your doctor may want you to have some blood tests from time to time to check on your kidneys, and also how much potassium is in your blood.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with valsartan. This is because some anti-inflammatory painkillers (such as aspirin and ibuprofen) may interfere with the way it works, and also may increase the risk of side-effects.

  • É muito importante que você siga quaisquer orientações dietéticas e de estilo de vida que seu médico possa ter lhe dado, como manter uma alimentação saudável, não fumar e praticar exercícios regularmente.

  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on valsartan because it will increase the risk of side-effects, such as feeling dizzy or faint.

  • Procure evitar substitutos de sal que contenham potássio. Isso porque os substitutos podem aumentar a quantidade de potássio no seu sangue, o que pode causar problemas.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking valsartan. This is because your blood pressure may drop too low if you are given some anaesthetics.

  • Treatment with valsartan is often long-term unless you experience an adverse effect. Continue to take it regularly, unless you are advised otherwise by your doctor.

Se você também estiver tomando hidroclorotiazida em combinação com este medicamento

  • Estudos sugerem que tomar doses mais altas de hidroclorotiazida por longos períodos de tempo pode aumentar o risco de certos tipos de câncer de pele.

  • Informe o seu médico se você já foi tratado para câncer de pele antes.

  • Informe seu médico sobre qualquer nova pinta ou alteração em pintas existentes, ou marcas preocupantes na sua pele.

  • Use protetor solar sob luz solar intensa. Não use camas de bronzeamento.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with valsartan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Valsartan side-effects


O que posso fazer se passar por isso?

Sentindo-se cansado ou tonto

Não dirija e não use ferramentas ou máquinas enquanto estiver afetado

Tummy (abdominal) pain, cough, headache, stomach upset

Se houver problemas, fale com seu médico

Importante: valsartan has been associated with an allergic-type reaction in a few people. Although this occurs only rarely, if you get any swelling of your mouth or face, speak with your doctor or go to your local accident and emergency department straightaway.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, fale com seu médico ou farmacêutico para mais orientações.

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

MHRA - Relatando reações adversas

Relate efeitos colaterais suspeitos de medicamentos, vacinas, cigarros eletrônicos, incidentes com dispositivos médicos, produtos defeituosos ou falsificados (falsos) à Agência Reguladora de Medicamentos e Produtos de Saúde para garantir o uso seguro e eficaz.

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Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.

Perguntas frequentes

What is the main purpose of valsartan medication?

Valsartan is primarily used to treat high blood pressure, improve heart function in people with heart failure, and protect the heart if someone has recently had a heart attack. It works by relaxing and widening blood vessels to reduce blood pressure and make it easier for the heart to pump blood.

Can I take valsartan with other medications for high blood pressure?

Yes, valsartan can be prescribed on its own or alongside other medicines for high blood pressure. Combination brands like Co-Diovan® (with hydrochlorothiazide) and Exforge® (with amlodipine) contain valsartan with other drugs to enhance blood pressure reduction and reduce the number of tablets you need to take.

Are there any specific over-the-counter medicines I should avoid while taking valsartan?

You should check with a pharmacist if any over-the-counter medicines are suitable to take with valsartan. Specifically, some anti-inflammatory painkillers such as aspirin and ibuprofen may interfere with valsartan's effectiveness and increase the risk of side-effects.

What should I do if I forget to take a dose of valsartan?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and take your next dose as usual. Do not take a double dose to compensate for a forgotten one.

How often will I need to see my doctor or have tests while on valsartan?

You should attend regular appointments with your doctor so they can monitor your progress and measure your blood pressure. Your doctor may also request blood tests periodically to check your kidney function and potassium levels in your blood.

Is it safe to drink alcohol while taking valsartan?

It is best to ask your doctor for advice regarding alcohol consumption while on valsartan. Your doctor might recommend avoiding alcohol as it can increase the risk of side-effects like feeling dizzy or faint.

What kind of dietary advice should I follow when taking valsartan?

It's important to follow any dietary advice given by your doctor, such as eating a healthy diet. You should also try to avoid salt substitutes that contain potassium, as these can increase potassium levels in your blood and potentially cause problems.

How should I store valsartan medication?

Valsartan should be stored in a cool, dry place, away from direct heat and light. Always keep all medicines out of the reach and sight of children.

Leitura adicional e referências

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão prevista: 17 Dez 2026
  • 18 Dez 2023 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
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