Can I take St John's wort and Vitamin C together?

Por que isso acontece

Vitamin C (ascorbic acid) and St John's Wort (Hypericum perforatum) are processed by the body through different pathways. Vitamin C is water-soluble and does not interfere with the liver enzymes (specifically the CYP450 system) that St John's Wort is known to affect. Furthermore, they do not have overlapping effects on the body's systems that would cause a conflict.

You can continue to take both supplements as directed. However, always inform your doctor or pharmacist about all supplements you are taking, as St John's Wort interacts with many prescription medicines, such as the contraceptive pill, blood thinners, and antidepressants.

Depressão e Saúde Mental

Como outros antidepressivos, a erva-de-são-joão pode aumentar o risco de pensamentos suicidas ou automutilação, especialmente ao iniciar o tratamento. Procure ajuda médica imediata se seu humor piorar.

Drug Interactions

St John's wort significantly reduces the effectiveness of many essential medicines, including the contraceptive pill, blood thinners (warfarin), epilepsy medications, and organ transplant drugs. Do not start it without a pharmacist checking your current medications.

Síndrome da Serotonina

Tomar hipericão junto com outros antidepressivos ou triptanos (para enxaqueca) pode causar síndrome serotoninérgica, uma condição potencialmente fatal que envolve febre alta, agitação e rigidez muscular.

Fotossensibilidade

A erva-de-são-joão pode tornar sua pele significativamente mais sensível à luz solar, levando a queimaduras solares graves ou reações na pele mesmo com exposição limitada.

Kidney stones (renal calculi)

High doses of vitamin C can increase the amount of oxalate in your urine, which significantly raises the risk of developing kidney stones, especially if you have had them before.

G6PD deficiency

Very high doses of vitamin C can cause oxidative stress and lead to the breakdown of red blood cells (haemolysis) in individuals with G6PD deficiency.

Álcool

It is best to avoid or strictly limit alcohol while taking St John's wort. Combining the two can increase drowsiness and dizziness, and may worsen the side effects of the herbal remedy.

Cafeína (Café, Chá, Bebidas Energéticas)

St John's wort can sometimes increase sensitivity to caffeine, leading to feelings of restlessness, anxiety, or a racing heart. Monitor your intake if you feel jittery.

Alimentos ricos em tiramina (por exemplo, queijos envelhecidos, carnes curadas, molho de soja, marmite, frutas maduras demais)

While less common than with older prescription antidepressants, St John's wort can potentially interact with tyramine-rich foods, leading to a sudden, dangerous increase in blood pressure (hypertensive crisis). You should consume these foods in moderation.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.