Can I take Apixaban and Naproxen together?

Por que isso acontece

Apixaban is an anticoagulant (blood thinner) that prevents clots by blocking a specific clotting factor. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that also thins the blood by preventing platelets from sticking together. Additionally, naproxen can irritate the lining of the stomach. When used together, their blood-thinning effects add up, making it much harder for your body to stop any bleeding that starts.

You should avoid taking naproxen while you are on apixaban unless your doctor has specifically told you to do so and is monitoring you closely. If you need pain relief, paracetamol is generally a safer alternative. If you have already taken both and notice any unusual bleeding, severe headache, or dark stools, seek medical attention immediately.

Combined use (Drug-Drug Interaction)

Do not take naproxen while taking apixaban unless specifically directed by a specialist. Taking both significantly increases your risk of life-threatening internal bleeding. Use paracetamol for pain relief instead.

Asma

Do not take naproxen if you have ever had wheezing, runny nose, or a skin rash after taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can trigger a severe or fatal asthma attack.

Stomach Ulcers

Avoid naproxen if you have a history of stomach ulcers or intestinal bleeding, as it can cause new bleeding or perforation of the stomach lining, which may be fatal.

Álcool

You should limit or avoid alcohol while taking these medicines. Both apixaban and naproxen increase your risk of bleeding in the stomach and intestines; drinking alcohol further irritates the stomach lining and can significantly increase this risk.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.