Can I take antihistamines with asthma?
Guia de interação medicamentosa
Publicado originalmente 30 Apr 2026
Atende aos diretrizes editoriais
- BaixarBaixar
- Compartilhar
- Language
- Discussão
- Versão em Áudio
While antihistamines are generally safe for people with asthma, older 'sedating' antihistamines (like chlorphenamine) can occasionally make asthma symptoms harder to manage by drying out the airways. Additionally, some people with asthma may have a higher risk of allergic reactions to certain ingredients in liquid medications.
Neste artigo:
Video picks for Interações medicamentosas
Continue lendo abaixo
Por que isso acontece
Older, first-generation antihistamines (like clorfenamina) have 'anticholinergic' effects. This means they can reduce the amount of mucus in the airways, making the remaining mucus thicker and harder to cough up. This can potentially irritate the lungs or make a cough feel more 'tight'. Modern, non-drowsy antihistamines (like cetirizine or loratadine) have very little of this effect.
O que você deve fazer
Voltar ao conteúdoIf you have asthma, it is usually best to choose a modern, non-drowsy antihistamine (such as cetirizina, loratadina, or fexofenadina) rather than older, sedating ones. Always keep your blue 'reliever' inhaler with you. If you notice your chest feeling tighter or your cough becoming drier and more difficult after starting an antihistamine, stop taking it and speak to your GP or pharmacist.
Continue lendo abaixo
Precauções importantes
Voltar ao conteúdoDrowsiness and impairment
These medicines can cause severe drowsiness and significantly impair your ability to drive or operate machinery. The effect is greatly increased if you drink alcohol.
Mental health changes
Montelukast can cause serious neuropsychiatric events, including agitation, sleep disturbances, depression, and suicidal thoughts. If you notice any change in mood or behaviour, stop the medicine and contact a doctor immediately.
Avisos sobre alimentos e bebidas
Voltar ao conteúdoÁlcool
It is best to avoid or strictly limit alcohol when taking antihistamines. Alcohol significantly increases the sedative effects of these medicines, making you much more drowsy, dizzy, and clumsy, which increases the risk of accidents.
Fruit Juices (Grapefruit, Orange, Apple)
Do not drink grapefruit, orange, or apple juice while taking fexofenadine. These juices can significantly reduce the amount of medicine your body absorbs, making the treatment less effective. It is best to take fexofenadine with water.
Char-grilled or Flame-broiled foods
Eating large amounts of char-grilled meat can speed up how quickly your body clears these medicines, potentially making your asthma treatment less effective.
Caffeine (Coffee, Tea, Energy drinks, Cola)
You should avoid or strictly limit drinks containing caffeine. Caffeine is chemically similar to theophylline and aminophylline and can increase the risk of side effects such as heart palpitations, tremors, anxiety, and difficulty sleeping.
High-protein or High-carbohydrate meals
Significant changes to your diet (such as starting a very high-protein or very high-carbohydrate diet) can change how your body processes theophylline and aminophylline. Consult your doctor before making major dietary changes.
Usando outros medicamentos
Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Patient picks for Interações medicamentosas

Verificador de interações medicamentosas
Can I take antihistamines with alcohol?
Combining alcohol with antihistamines can make you feel extremely drowsy, dizzy, and unsteady on your feet. It can also slow down your breathing and significantly impair your coordination and judgement. This effect is much stronger with older 'sedating' antihistamines (like chlorphenamine or promethazine), but it can also happen with newer 'non-drowsy' versions (like cetirizine or loratadine).

Verificador de interações medicamentosas
Can I give my child antihistamines?
Antihistamines can affect children differently than adults. While they usually cause sleepiness, they can sometimes cause 'paradoxical excitation,' making a child hyperactive, shaky, or unable to sleep. In very young children (under 6), some older antihistamines can cause serious breathing problems or severe drowsiness.
Continue lendo abaixo
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
30 Apr 2026 | Publicado originalmente

Pergunte, compartilhe, conecte-se.
Navegue por discussões, faça perguntas e compartilhe experiências em centenas de tópicos de saúde.

Sentindo-se mal?
Avalie seus sintomas online gratuitamente
Inscreva-se no boletim informativo do Patient
Sua dose semanal de conselhos de saúde claros e confiáveis - escritos para ajudá-lo a se sentir informado, confiante e no controle.
By subscribing you accept our Política de Privacidade. Você pode cancelar a inscrição a qualquer momento. Nunca vendemos seus dados.