mitochondrially encoded cytochrome b
Última atualização 18 de ago de 2020
Atende aos diretrizes editoriais
- BaixarBaixar
- Compartilhar
- Language
- Discussão
- Versão em Áudio
- Adicionar às fontes preferidas no Google
A MT-CYB gene provides instructions for making a protein called cytochrome b. This protein plays a key role in structures called mitochondria, which convert the energy from food into a form that cells can use. Cytochrome b is one of 11 components of a group of proteins called complex III. In mitochondria, complex III performs one step of a process known as oxidative phosphorylation, in which oxygen and simple sugars are used to create adenosine triphosphate (ATP), the cell's main energy source. During oxidative phosphorylation, the protein complexes, including complex III, drive the production of ATP through a step-by-step transfer of negatively charged particles called electrons. Cytochrome b is involved in the transfer of these particles through complex III.
Normal function
A MT-CYB gene provides instructions for making a protein called cytochrome b. This protein plays a key role in structures called mitochondria, which convert the energy from food into a form that cells can use. Cytochrome b is one of 11 components of a group of proteins called complex III. In mitochondria, complex III performs one step of a process known as oxidative phosphorylation, in which oxygen and simple sugars are used to create adenosine triphosphate (ATP), the cell's main energy source. During oxidative phosphorylation, the protein complexes, including complex III, drive the production of ATP through a step-by-step transfer of negatively charged particles called electrons. Cytochrome b is involved in the transfer of these particles through complex III.
Although most DNA is packaged in chromosomes within the nucleus (nuclear DNA), mitochondria also have a small amount of their own DNA, called mitochondrial DNA (mtDNA). This type of DNA contains many genes essential for normal mitochondrial function. Cytochrome b is the only component of complex III that is produced from a gene found in mitochondrial DNA.
Conditions referring to this gene or chromosome
Other names
COB
CYTB
cytochrome b
cytochrome b (mitochondrion) [Homo sapiens]
MTCYB
UQCR3
Related patient information and medicines
Patient information leaflet
Posso tomar Black cohosh e Glucosamina juntos?
Both are generally c... Why this happens These two substances are processed by the body through different pathways. Glucosamine is an amino sugar used by the body to build cartilage, while black cohosh is a herbal remedy that primarily affects hormonal pathways or neurotransmitters. They do not compete for the same enzymes in the doença hepática (such as.
Patient information leaflet
Vacina 6 em 1
The 6-in-1 vaccine is part of routine childhood immunisations and protects babies against six different serious illnesses. Three doses are given. Further boosters without all six components are given at other times later in childhood and in adult life. The 6-in-1 vaccine used to be given as the 3-in-1 vaccine DTaP along with the polio vaccine.
Patient information leaflet
Posso tomar Prometazina e Vitamina D3 juntos?
It is generally considered sa... Why this happens Promethazine is an antihistamine processed primarily by the liver's cytochrome P450 enzymes, while vitamin D3 is a fat-soluble vitamin that undergoes a different metabolic pathway (hydroxylation in the liver and kidneys). They do not interfere with each other's absorption, metabolism, or effects in.
Patient information leaflet
Posso tomar Glucosamina e Erva-de-São-João juntos?
T... It is generally considered safe to take these two supplements together. Why this happens Glucosamine is primarily used by the body to build cartilage and does not significantly affect the liver enzymes (Cytochrome P450) that St John's wort is known to influence. St John's wort works by altering brain chemicals and speeding up the breakdown of.
Patient information leaflet
Posso tomar Black cohosh e Vitamina C juntos?
Why this happens Black cohosh and vitamin C are processed by the body th... Vitamin C is a water-soluble vitamin that does not significantly interfere with the liver enzymes (such as the Cytochrome P450 system) that process black cohosh. Additionally, they do not have overlapping effects that would cause a dangerous build-up or a reduction in.
Medicine leaflet
Vacina de mRNA contra COVID-19
Drink plenty of fluids and rest if possible. About COVID-19 mRNA vaccine (Comirnaty®, Spikevax®) Type of medicine COVID-19 mRNA vaccine Used for Protection against infection caused by SARS-CoV-2 virus, original and Omicron variants Also called Comirnaty® 'Pfizer BioNTech' vaccine; 'Moderna' Spikevax® vaccine Available as Multi-dose injection vials.
Leitura adicional e referências
- mitochondrially encoded cytochrome b; MedlinePlus, National Library of Medicine.
- Andreu AL, Hanna MG, Reichmann H, Bruno C, Penn AS, Tanji K, Pallotti F, Iwata S, Bonilla E, Lach B, Morgan-Hughes J, DiMauro S. Exercise intolerance due to mutations in the cytochrome b gene of mitochondrial DNA. N Engl J Med. 1999 Sep 30;341(14):1037-44. doi: 10.1056/NEJM199909303411404.
- Blakely EL, Mitchell AL, Fisher N, Meunier B, Nijtmans LG, Schaefer AM, Jackson MJ, Turnbull DM, Taylor RW. A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast. FEBS J. 2005 Jul;272(14):3583-92. doi: 10.1111/j.1742-4658.2005.04779.x.
- Gil Borlado MC, Moreno Lastres D, Gonzalez Hoyuela M, Moran M, Blazquez A, Pello R, Marin Buera L, Gabaldon T, Garcia Penas JJ, Martin MA, Arenas J, Ugalde C. Impact of the mitochondrial genetic background in complex III deficiency. PLoS One. 2010 Sep 17;5(9):e12801. doi: 10.1371/journal.pone.0012801.
- Meunier B, Fisher N, Ransac S, Mazat JP, Brasseur G. Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases. Biochim Biophys Acta. 2013 Nov-Dec;1827(11-12):1346-61. doi: 10.1016/j.bbabio.2012.11.015. Epub 2012 Dec 5.
Participe da conversa
Compartilhe seus pensamentos ou experiências com outros em nosso comunidades de pacientes.
Pergunte, compartilhe, conecte-se.
Navegue por discussões, faça perguntas e compartilhe experiências em centenas de tópicos de saúde.
Inscreva-se no boletim informativo do Patient
Sua dose semanal de conselhos de saúde claros e confiáveis - escritos para ajudá-lo a se sentir informado, confiante e no controle.
Ao se inscrever, você aceita nossos Política de Privacidade. Você pode cancelar a inscrição a qualquer momento. Nunca vendemos seus dados.