Lactulose for constipation
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 16 Out 2023
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Lactulose can take up to 48 hours to have an effect.
If you find the medicine makes you feel queasy, mix your dose with some water or fruit juice. Alternatively, take your doses with a meal.
Eating a healthy diet, drinking plenty of water and getting regular gentle exercise can all help prevent constipation.
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About lactulose
Tipo de medicamento | An osmotic laxative |
Usado para | Constipação |
Disponível como | Oral liquid medicine, liquid sachets |
Constipação is a common problem. It can mean either going to the toilet less often than usual to empty your bowels, or passing hard or painful stools. Constipation can be caused by a number of things. Not eating enough fibre or not drinking enough fluid can cause constipation. Some conditions (such as pregnancy) can cause constipation, as can a lack of exercise or movement (such as being ill in bed) and some medicines.
Often, increasing the amount of fibre in your diet (such as by eating more fruit, vegetables, cereals, and wholemeal bread) and drinking plenty of water each day can effectively prevent or relieve constipation. You will have been recommended lactulose, a laxative, to help relieve constipation if you cannot increase the fibre in your diet or if this is insufficient. Lactulose works by drawing fluid into your bowel, which makes your stools softer and easier to pass. It is available on prescription, and it can also be bought without a prescription at pharmacies.
Lactulose also changes the acidity of the stools and this helps to discourage the growth of some germs (bacteria) present in the bowel. Because of this, lactulose is also prescribed for people with a liver disease called hepatic encephalopathy. If you have been prescribed it for this reason, ask your doctor if you need further information about the medicine.
Before taking lactulose
Voltar ao conteúdoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lactulose it is important that your doctor or pharmacist knows:
If you are so constipated that you think you may have a blockage.
If you are unable to digest milk sugar (lactose intolerant).
If you have a condition called galactosaemia, where your body cannot process galactose.
If you are pregnant or breastfeeding. Lactulose is not known to be harmful to a baby, but while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
If it is intended for a child. This is because laxatives should only be given to children on the advice of a doctor or healthcare professional.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to this or to any other medicine.
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How to take lactulose
Voltar ao conteúdoBefore you start the treatment, read the manufacturer's printed information leaflet from the pack. It will give you more information about lactulose and will provide you with a full list of the side-effects which you may experience.
Take lactulose exactly as your doctor tells you to, or as directed on the pack. The usual dose for constipation in an adult is 15 ml (three 5 ml spoonfuls) twice daily, although the dose you are advised to take may be different from this as it will be adjusted to suit your needs.
If a doctor or healthcare professional has recommended lactulose for your child, check the label on the pack carefully to make sure that you give the correct dose for the age of your child.
If you forget to take a dose, do not worry, just take the next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Obtendo o máximo do seu tratamento
Voltar ao conteúdoLactulose can take up to 48 hours to act, so it may take two or three days before you feel the full benefit. However, if after several days you do not feel your symptoms are improving, or if they get worse, you should speak with a doctor for further medical advice.
It is important for you to drink plenty while you are constipated. Adults should aim to drink at least two litres (about 8-10 cups) of fluid per day. Most sorts of drink will do, but as a start, try just drinking a glass of water 3-4 times a day in addition to what you normally drink.
Try to eat a balanced diet containing high-fibre foods such as wholemeal and wholegrain breads and cereals, fruit and vegetables, brown rice and wholemeal pasta. If you are not used to a high-fibre diet, it may be best to increase the amount of fibre you eat gradually.
Keeping your body active will help you to keep your digestive system moving, so try to take some regular daily exercise.
You may wish to include some foods in your diet that contain sorbitol. Sorbitol is a naturally occurring sugar. It is not digested very well and draws water into your bowel which has an effect of softening stools. Fruits (and their juices) that have a high sorbitol content include apples, apricots, gooseberries, grapes (and raisins), peaches, pears, plums, prunes, raspberries and strawberries.
You can read more about how to prevent or treat constipation in the separate health information leaflets called Constipação (para adultos) e Constipação em Crianças.
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Can lactulose cause problems?
Voltar ao conteúdoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones which can occur with lactulose. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Lactulose side-effects | O que posso fazer se passar por isso? |
Excess wind (flatulence), tummy (abdominal) discomfort or cramps | These effects soon settle down as your body adjusts but if they continue or become troublesome, speak with your doctor or pharmacist for further advice |
Feeling sick (nausea) or being sick (vomiting) | Try taking lactulose with meals, or mixing your dose with some water or fruit juice |
Se você sentir quaisquer outros sintomas que acha que podem ser devido ao medicamento, fale com seu médico ou farmacêutico para mais conselhos.
How to store lactulose
Voltar ao conteúdoKeep all medicines out of the sight and reach of children.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Voltar ao conteúdoInformações importantes sobre todos os medicamentos
Se você comprar qualquer medicamento, verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Nunca tome mais do que a dose prescrita. Se suspeitar que você ou outra pessoa possa ter tomado uma overdose deste medicamento, vá ao departamento de acidentes e emergências do hospital local. Leve o recipiente com você, mesmo que esteja vazio.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando.
Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy who will dispose of them for you.
Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do site Cartão Amarelo.
Vídeos selecionados para Tratamento gastrointestinal

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Leitura adicional e referências
- Manufacturer's PIL, Duphalac 3.335 g/5 ml Oral Solution; Mylan Products Ltd, The electronic Medicines Compendium. Dated April 2022.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Próxima revisão prevista para: 15 de out. de 2026
16 Out 2023 | Última versão

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