Posso tomar Sertralina e Trazodona juntos?

You should only take sertralina e trazodone together if they have been specifically prescribed by your doctor. Combining them can increase the risk of síndrome serotoninérgica.

Por que isso acontece

Both sertraline and trazodone increase the levels of serotonin in the brain. When used together, these effects add up (pharmacodynamic interaction), potentially leading to an overload. Additionally, both drugs can have a sedative effect, which is increased when they are combined.

You may be experiencing an interaction between sertraline and trazodone if you have:

• Agitação ou inquietação.

• Confusão.

• Batimentos cardíacos rápidos.

• Sweating more than usual.

• Shivering or goosebumps.

• Muscle twitching or stiffness.

• Diarreia.

• Febre.

If you experience any of these symptoms, seek medical help immediately.

• Take them only if your doctor has prescribed them together.

• Be aware of symptoms of serotonin syndrome, such as shivering, sweating, a very high temperature, fast heartbeat, muscle twitching, or agitation.

• Avoid driving or using machinery until you know how this combination affects you.

Pensamentos suicidas e automutilação

Antidepressants can increase the risk of suicidal thoughts or self-harm, particularly in the first few weeks of treatment or when the dose is changed. Patients and their families should monitor for any changes in mood or behaviour.

Síndrome da Serotonina

Taking these medicines together increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience agitation, hallucinations, rapid heartbeat, shivering, or severe muscle stiffness.

Distúrbios de sangramento

These medicines can increase your risk of bleeding, especially in the stomach. This risk is higher if you also take aspirin, ibuprofen (NSAIDs), or blood-thinning medications like warfarin.

Priapismo (ereção prolongada)

Trazodone can cause a painful, persistent erection that lasts for several hours. This is a medical emergency; if this occurs, stop taking the medicine and go to an A&E department immediately to avoid permanent damage.

Álcool

It is best to avoid or strictly limit alcohol while taking these medicines. Combining alcohol with sertraline or trazodone can significantly increase drowsiness, dizziness, and coordination problems. It may also worsen your underlying condition.

Suco de toranja

Você deve evitar consumir grandes quantidades de suco de toranja enquanto estiver tomando sertralina. A toranja pode aumentar o nível de sertralina no seu sangue, o que pode aumentar o risco de efeitos colaterais.

Grapefruit juice can increase the amount of trazodone in your blood, which may increase the risk of side effects like extreme sleepiness or heart rhythm problems. It is best to avoid drinking large amounts of grapefruit juice.

Cafeína (Café, Chá, Bebidas Energéticas)

Sertraline can sometimes make you feel restless or shaky. High amounts of caffeine can worsen these feelings. Monitor how you feel and consider reducing caffeine if you experience increased anxiety or tremors.

Alimentação (Geral)

Trazodone should ideally be taken after a meal or a snack. Taking it on an empty stomach can increase the risk of dizziness or lightheadedness.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.