Can I take Aspirin and Methotrexate together?

Por que isso acontece

Aspirin interferes with how your kidneys remove methotrexate from your body. It also 'bumps' methotrexate off the proteins in your blood that normally keep it inactive, leaving more of the active drug to cause potential harm.

Do not take aspirin (including low-dose 'baby' aspirin) while taking methotrexate unless your specialist doctor has specifically told you to do so. If you need pain relief, paracetamol is usually a safer choice. If you are already taking both, contact your doctor immediately if you notice unusual bruising, bleeding, a sore throat, or mouth ulcers.

Gravidez e concepção

Methotrexate causes severe birth defects. Both men and women must use effective contraception during treatment and for at least 6 months after stopping. Stop immediately and see a doctor if pregnancy is suspected.

Asma

Não tome aspirina se você tem histórico de asma desencadeada por aspirina ou outros anti-inflamatórios não esteroides (AINEs), pois isso pode causar um ataque de asma potencialmente fatal.

Infection and blood disorders - methotrexate

Seek urgent medical attention for signs of infection (fever, sore throat) or unexplained bruising/bleeding. Methotrexate can severely suppress your immune system and bone marrow.

Álcool

You should strictly limit or avoid alcohol while taking methotrexate. Both alcohol and methotrexate can stress the liver; combining them significantly increases your risk of serious liver damage (cirrhosis or scarring).

Cafeína (Café, Chá, Refrigerante)

High amounts of caffeine may reduce how well methotrexate works for some conditions like rheumatoid arthritis. Try to keep your intake of coffee, tea, and caffeinated soft drinks consistent and moderate.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.