Can I take Aspirin and Diclofenac together?
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Publicado originalmente 25 Jan 2026
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Taking aspirin and diclofenac together significantly increases your risk of developing stomach ulcers, internal bleeding, and kidney problems. Both medicines belong to the same family (NSAIDs), and using them together 'doubles up' the risk of side effects without providing much extra pain relief.
Neste artigo:
You should not take aspirina e diclofenaco together unless specifically instructed by your doctor.
Both drugs work by blocking enzymes (COX-1 and COX-2) that protect the lining of your stomach and keep your kidneys working properly.
When you take both, the protective layer in your stomach is weakened further, and blood flow to the kidneys can be reduced. Additionally, both drugs thin the blood, making any bleeding more difficult to stop.
If you must take both, your doctor may prescribe a 'stomach protector' medicine (such as omeprazole).
If you are taking low-dose aspirin for heart protection, speak to your GP or pharmacist before using diclofenac, as diclofenac can interfere with aspirin's heart-protective benefits and increase your risk of a stomach bleed.
How to know if you're having a drug interaction?
You may be experiencing an interaction between aspirin and diclofenac if you have:
Stomach pain, indigestion, or heartburn.
Náusea ou vômito.
Black, tarry stools or blood in your stools.
Vômito com sangue.
Unusual bruising or bleeding.
Dizziness or headaches.
Swelling of the ankles or feet.
Shortness of breath or chest pain (rare but serious).
O que você deve fazer
Voltar ao conteúdoSe você tiver algum dos sintomas acima, você deve:
Stop taking the medicines and contact your GP or pharmacist if you develop stomach pain, indigestion, nausea, unusual bruising or mild bleeding.
Seek urgent medical help (call 999 / go to A&E) if you have:
Black, tarry poo.
Vomit (sick) that looks like blood or coffee grounds.
Severe stomach pain.
Chest pain or shortness of breath.
Signs of an allergic reaction (swelling of face/lips, difficulty breathing).
Do not restart either medicine until you have spoken to a healthcare professional.
Continue lendo abaixo
Precauções importantes
Voltar ao conteúdoAsma
Do not take these medicines if you have asthma and have ever had a flare-up or breathing difficulties triggered by aspirin or other NSAIDs. This can cause a life-threatening allergic reaction or severe asthma attack.
Stomach ulcers or bleeding
Avoid these medicines if you have a history of stomach ulcers or gastrointestinal bleeding. They significantly increase the risk of serious stomach damage and internal bleeding.
Gravidez (terceiro trimestre)
Do not take these medicines if you are more than 20 weeks pregnant. They can cause serious kidney or heart problems in the unborn baby and may lead to complications during delivery.
Avisos sobre alimentos e bebidas
Voltar ao conteúdoÁlcool
Drinking alcohol while taking these medicines increases the risk of irritation and bleeding in your stomach and intestines. It is best to avoid or limit alcohol consumption.
Cafeína (café, chá, bebidas energéticas)
Aspirin can increase the effects of caffeine, potentially leading to jitteriness, a racing heart, or difficulty sleeping. Additionally, both caffeine and aspirin can irritate the stomach lining, increasing the risk of indigestion or ulcers when combined.
Continue lendo abaixo
Usando outros medicamentos
Voltar ao conteúdoTomando vários medicamentos? Nosso Verificador de Interações de Medicamentos ajuda você a verificar se suas prescrições, medicamentos de venda livre e suplementos são seguros para serem tomados juntos. Basta procurar seus medicamentos para ver possíveis interações e o que fazer sobre elas.
Aviso Legal
Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.
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Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
25 Jan 2026 | Publicado originalmente

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