Comprimidos de Ponatinibe

About ponatinib

Ponatinib is a medicine which is given to treat some types of leucemia. Leukaemia is cancer of cells in the bone marrow - these are the cells which develop into blood cells. Ponatinib is given for the types of leukaemia called leucemia mieloide crônica (LMC) e leucemia linfoblástica aguda (LLA).

In cancer, certain cells in the body grow and multiply in a way that is 'out of control'. Chemotherapy (anti-cancer) medicines work by inhibiting the way cells grow and increase in number. Ponatinib belongs to a group of anti-cancer medicines which work by blocking the chemical messengers which send signals to cells to grow. This stops the production of cancer cells.

Before taking ponatinib

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking ponatinib it is important that your doctor knows:

• Se você estiver com uma infecção ou se sentir especialmente mal.

• Se você tiver algum problema com o funcionamento do seu fígado ou se já teve infecção por hepatite B.

• Se você já teve algum transtorno no pâncreas, chamado pancreatite.

• If you drink large amounts of alcohol.

• If you have been told you have high levels of fats called triglycerides in your blood.

• Se você tem uma condição cardíaca ou doença dos vasos sanguíneos.

• Se você está grávida ou amamentando.

• Se você estiver tomando ou usando qualquer outro medicamento. Isso inclui quaisquer medicamentos que você esteja tomando e que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

• Se você já teve uma reação alérgica a um medicamento.

How to take ponatinib tablets

• Before you start the treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside the pack of tablets. These will give you more information about ponatinib and will provide a full list of the side-effects which you may experience from taking it.

• Ponatinib will be prescribed for you by a specialist doctor who is experienced in treating your condition. It is important that you take the tablets exactly as you are told to. It is usual to take one 45 mg tablet daily, although your dose may be different to this. The directions for taking the tablets will be printed on the label of the pack to remind you what your doctor has told you to do, but if you have any concerns or questions, you should contact your doctor or hospital clinic for further advice.

• You can take ponatinib tablets before or after meals. Swallow the tablet whole with a drink of water - do not crush or chew the tablet.

• If you forget to take a dose, make sure that you remember to take your next dose when it is due. Do not take two doses on the same day to make up for a forgotten dose.

Obtendo o máximo do seu tratamento

• Você deve tentar manter seus compromissos regulares com seu médico ou hospital. Isso é para que seu médico possa acompanhar seu progresso. Você precisará fazer exames de rotina durante o tratamento.

• Ponatinib can lower the number of white cells in your blood and this increases the chance that you may get an infection. You should take precautions to reduce the risk of infection whenever you can. So, if possible, avoid other people with infections and let your doctor know straightaway if you think you are getting a sore throat or if you have a high temperature.

• If you buy or take any other medicines, check with a pharmacist that they are suitable to take alongside ponatinib.

• Se você estiver passando por uma cirurgia ou tratamento dentário, sempre informe a pessoa que está realizando o procedimento quais medicamentos você está tomando.

• It is important that you do not get pregnant or father a child while you are taking ponatinib. If this could be a possibility for you, make sure you discuss with your doctor which types of contraception are suitable for you and your partner.

Can ponatinib cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ponatinib. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, fale com seu médico ou farmacêutico.

How to store ponatinib

• Mantenha todos os medicamentos fora do alcance e da vista das crianças.

• Armazene em local fresco e seco, longe de calor e luz diretos.

• Please return any unused or unwanted tablets to your clinic or pharmacy to destroy.

Informações importantes sobre todos os medicamentos