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Glyceryl trinitrate rectal ointment

Rectogesic

Glyceryl trinitrate rectal ointment can ease the pain associated with small tears of skin around the back passage (anal fissures).

Use the ointment twice daily at 12-hourly intervals. You can use it for up to eight weeks if necessary.

The most common side-effect is a headache.

Em resumo

  • Glyceryl trinitrate rectal ointment eases pain from anal fissures by increasing blood flow.

  • It is applied inside the back passage every 12 hours for up to eight weeks.

  • Common side-effects include headache and feeling light-headed or dizzy.

  • Do not drink alcohol while using this ointment as it increases side-effects.

  • Tell your doctor if symptoms do not improve or if you experience bleeding from your back passage.

  • Store the ointment in a cool, dry place and discard it eight weeks after opening.

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About glyceryl trinitrate rectal ointment

Tipo de medicamento

A nitrate

Usado para

Pain relief for anal fissures (in adults)

Também chamado de

Nitroglycerin (in US); Rectogesic®

Disponível como

Rectal ointment

Uma fissura anal is a small tear of the skin around your back passage (anus). Glyceryl trinitrate (GTN) rectal ointment (Rectogesic®) works by relaxing the muscle just inside your back passage. Relaxing this muscle increases the flow of blood to the area, which eases pain. It can be helpful where other treatments have not been effective.

A different brand of glyceryl trinitrate ointment (Percutol®) is used to relieve angina pain. For information on this product please see our medicine leaflet Glyceryl trinitrate for angina.

To make sure that this is the right treatment for you, before you start using GTN rectal ointment it is important that your doctor knows:

  • Se você está grávida ou amamentando.

  • Se você tiver algum problema com o funcionamento do seu fígado, ou qualquer problema com o funcionamento dos seus rins.

  • If you have migraines or severe headaches.

  • If you have low blood pressure, or a heart condition.

  • If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia).

  • Se você tem uma glândula tireoide hipoativa.

  • Se você tem uma condição ocular chamada glaucoma.

  • If you have recently had a head injury or a heart attack.

  • Se você já teve uma reação alérgica a um medicamento.

  • If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction.

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  • Before you use the ointment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using the ointment, and it will also provide you with a full list of side-effects which you could experience.

  • Cover your finger with a finger cot (available from pharmacies), or a piece of cling film, or use a disposable glove. Then measure out 2.5 cm of the ointment from the tube on to your finger (there is a measuring line on the packaging to help you). Then, using your finger, gently insert the ointment just inside your back passage. To make sure that the ointment gets to the correct place, insert your finger to the first finger joint. Apply the ointment this way every 12 hours until the pain goes away. You can continue to use the ointment for up to eight weeks, if needed.

  • Remember to follow any lifestyle or dietary advice you have been given by your doctor. Try to avoid becoming constipated, by eating a high-fibre diet and drinking several glasses of water each day.

  • It is best not to drink alcohol while you are using GTN rectal ointment. Alcohol will increase the chance that you experience side-effects such as feeling dizzy and light-headed.

  • If you experience any bleeding from your back passage, or if your symptoms do not improve, you should discuss this with your doctor.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take while you are using GTN rectal ointment.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with GTN rectal ointment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common glyceryl trinitrate rectal ointment side-effects (these affect more than 1 in 10 people)

O que posso fazer se passar por isso?

Dor de cabeça

Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or if it continues, please ask your doctor for further advice

Common glyceryl trinitrate rectal ointment side-effects (these affect fewer than 1 in 10 people)

O que posso fazer se passar por isso?

Sentindo-se tonto ou com vertigem

Não dirija e não use ferramentas ou máquinas enquanto estiver afetado

Sentindo-se enjoado (náusea)

Try to stick to simple meals (avoid rich or spicy foods). If it becomes troublesome, please speak with your doctor

Less common glyceryl trinitrate rectal ointment side-effects

O que posso fazer se passar por isso?

Blurred vision, diarrhoea, local burning or itching

If any become troublesome, please speak with your doctor

If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.

  • Once opened, do not store or use the ointment for longer than eight weeks.

  • Mantenha todos os medicamentos fora do alcance e da vista das crianças.

  • Armazene em local fresco e seco, longe de calor e luz diretos.

Informações importantes sobre todos os medicamentos

Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Este medicamento é para você. Nunca o dê a outras pessoas, mesmo que a condição delas pareça ser a mesma que a sua.

Se você estiver passando por uma cirurgia ou tratamento dentário, lembre-se de informar à pessoa que está realizando o procedimento quais medicamentos você está tomando/usando.

Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.

Se você tiver alguma dúvida sobre este medicamento, pergunte ao seu farmacêutico.

Relatar efeitos colaterais de um medicamento ou vacina

Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

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Perguntas frequentes

How should I store glyceryl trinitrate rectal ointment?

You should store the ointment in a cool, dry place, away from direct heat and light. It's important to keep all medicines out of the reach and sight of children. Once you've opened the tube, do not store or use the ointment for longer than eight weeks.

What should I do if my symptoms don't improve or if I experience bleeding?

If you notice any bleeding from your back passage, or if your symptoms do not get better despite using the ointment as directed, you should discuss this with your doctor.

What should I do if I accidentally use too much ointment?

Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, you should go to the accident and emergency department of your local hospital immediately. Remember to take the ointment container with you, even if it's empty.

Are there any specific situations where I need to mention I'm using this ointment to other healthcare professionals?

Yes, if you are having an operation or dental treatment, it's very important to tell the person carrying out the treatment which medicines you are taking or using, including glyceryl trinitrate rectal ointment.

Can I use other medicines, including over-the-counter ones, with glyceryl trinitrate rectal ointment?

If you are considering buying any other medicines, including those available without a prescription, you should check with a pharmacist to ensure they are suitable for you to take while you are using GTN rectal ointment. It's particularly important to inform your doctor about any medicines you are using to treat erectile dysfunction, as well as any herbal or complementary medicines.

Leitura adicional e referências

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Sobre o autorVer biografia completa

Imagem do autor

Michael Stewart, MRPharmS

Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico

BPharm (Hons), MRPharmS

Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.

Sobre o revisor

Imagem do autor

Sid Dajani

Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.

Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • Próxima revisão agendada: 16 de out. de 2027
  • 20 Out 2024 | Última versão

    Última atualização por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani
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