Preparações de clindamicina para acne
Dalacin T, Zindaclin
Revisado por Sid DajaniÚltima atualização por Michael Stewart, MRPharmSÚltima atualização 18 de maio de 2023
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Clindamycin is an antibiotic - to treat acne, it is applied to the skin as a lotion, solution, or gel.
Apply the preparation to all of the affected area of skin, not just to individual spots.
The most common side-effect is mild skin irritation.
Em resumo
Clindamycin is an antibiotic skin preparation used to treat acne.
It is available as a solution, lotion, or gel.
You should apply it exactly as your doctor tells you, usually once or twice daily.
Common side effects include skin irritation, itching, dryness, or oiliness.
Consult your doctor if you experience diarrhoea while using this preparation.
About clindamycin skin preparations
Tipo de medicamento | An antibiotic skin preparation |
Usado para | Acne |
Também chamado de | Dalacin T®; Zindaclin®; Duac® Once Daily (clindamycin with peróxido de benzoíla); Treclin® (clindamycin with tretinoin) |
Disponível como | Solution, lotion and gel |
Acne is the common cause of spots. Most people with acne are aged between 12 and 25 years, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing inflamed spots.
Antibiotics like clindamycin, work by stopping bacteria that can contribute to acne from multiplying. One brand of clindamycin (Duac® Once Daily gel) also contains peróxido de benzoíla, which helps to unplug blocked pores. Clindamycin is also available in combination with tretinoin in a gel called Treclin®.
Clindamycin is also available as capsules to take by mouth, and as a cream for vaginal infection. These are used for other conditions, not acne. There are two separate medicine leaflets available which provide more information about these, called Cápsulas de clindamicina para infecção e Creme de clindamicina para vaginose bacteriana.
Before using clindamycin skin preparations
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using clindamycin on your skin, it is important that your doctor knows:
If you are pregnant or breastfeeding. (Although using clindamycin lotion is not known to be harmful to an unborn baby, you should let your doctor know if you think you are pregnant.)
Se você tiver algum problema intestinal que cause diarreia.
Se você já teve uma reação alérgica a um medicamento ou a uma preparação para a pele.
How to use clindamycin skin preparations
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about clindamycin, and it will also explain how to use the preparation you have been prescribed.
Apply the preparation exactly as your doctor tells you to. Wash and gently dry your skin, and then apply a thin layer to the whole of the area where your spots occur. The label on the pack will tell you how many times a day to use the preparation. Some clindamycin skin preparations are used once each day, others are used twice a day. Wash your hands well after using it.
Dalacin T® topical solution contains a small amount of alcohol which can cause stinging if it gets into grazes, or on to sensitive areas of skin. If you are using this brand of clindamycin, try to avoid getting it on areas of your skin in or around your nostrils, your eyes and your mouth.
Obtendo o máximo do seu tratamento
Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. A full course of treatment may last for several months.
It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water may worsen acne. Do not wash more than you normally do. You cannot clean off blackheads.
During your treatment your doctor may ask you to use another (non-antibiotic) skin preparation from time to time. It is important that you follow your doctor's advice, as this is to help prevent your spots from becoming resistant to treatment.
Can clindamycin skin preparations cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clindamycin when used on the skin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common clindamycin side-effects (these affect more than 1 in 10 people) | O que posso fazer se passar por isso? |
Skin irritation, itching, dryness or oiliness | Stop using the preparation for a day or so to allow your skin to recover. These effects usually reduce as your skin gets used to the preparation, but if they continue or become troublesome, you should speak with your doctor |
Less common clindamycin side-effects (these affect fewer than 1 in 100 people) | O que posso fazer se passar por isso? |
Diarreia | Contact your doctor for further advice before applying any more of the preparation |
If you experience any other symptoms which you think may be due to the preparation, speak with your doctor or pharmacist.
How to store clindamycin skin preparations
Mantenha todos os medicamentos fora do alcance e da vista das crianças.
Armazene em local fresco e seco, longe de calor e luz diretos.
Informações importantes sobre todos os medicamentos
Informações importantes sobre todos os medicamentos
This preparation is for external use only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Se você comprar qualquer medicamento, verifique com um farmacêutico se é seguro tomá-lo com seus outros medicamentos.
Se você for se submeter a uma operação ou tratamento dentário, informe à pessoa que está realizando o tratamento quais medicamentos você está tomando ou usando.
This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.
Não guarde medicamentos vencidos ou indesejados. Leve-os à sua farmácia local, que se encarregará de descartá-los para você.
If you have any questions about this preparation, ask your pharmacist for further advice.
Relatar efeitos colaterais de um medicamento ou vacina
Se você sentir efeitos colaterais, pode relatá-los online através do Site do Yellow Card.

Inseguro sobre misturar medicamentos?
Verifique possíveis interações entre medicamentos, suplementos e alimentos antes de tomá-los juntos.
Perguntas frequentes
Are there different forms of clindamycin for acne?
Yes, clindamycin for acne is available as a solution, lotion, and gel. It can also be found in combination preparations, such as Duac® Once Daily gel, which includes benzoyl peroxide, and Treclin® gel, which contains tretinoin.
How do clindamycin skin preparations help with acne?
Clindamycin is an antibiotic that works by stopping the proliferation of bacteria that contribute to acne. Some combination products, like Duac® Once Daily gel, also contain ingredients (benzoyl peroxide) that help to unblock pores.
What should I do if I am pregnant or breastfeeding and considering using clindamycin skin preparations?
It's important to inform your doctor if you are pregnant or breastfeeding. While using clindamycin lotion is not known to be harmful to an unborn baby, your doctor needs to be aware of your situation.
When should I apply clindamycin skin preparations?
You should apply the preparation exactly as instructed by your doctor. Typically, you wash and gently dry your skin, then apply a thin layer to the entire area affected by spots. The frequency of application (once or twice daily) will be indicated on the product label and by your doctor. Always remember to wash your hands well after applying it.
Can clindamycin skin preparations be used for other types of infections?
While clindamycin is an antibiotic, the skin preparations discussed are specifically for acne. Clindamycin also comes in capsules for oral use and a cream for vaginal infections, but these forms are used for different conditions and not for acne.
Leitura adicional e referências
- Manufacturer's PIL, Dalacin® T Topical Solution/Topical Lotion; Pfizer Limited, The electronic Medicines Compendium. Dated February 2021.
- Medicamentos Completo BNF 89ª Edição; Associação Médica Britânica e Sociedade Real de Farmácia da Grã-Bretanha, Londres.
Sobre o autorVer biografia completa

Michael Stewart, MRPharmS
Gerente de Revisão de Folhetos de Medicamentos – Contratado, Farmacêutico
BPharm (Hons), MRPharmS
Michael é um farmacêutico comunitário atuando nas Midlands e em South Yorkshire, com mais de 20 anos de experiência em aconselhamento sobre medicamentos e condições médicas. Ele tem uma sólida formação em treinamento em saúde, tendo produzido e ministrado cursos de treinamento para equipes de farmácia e funcionários de ambientes de cuidados residenciais, incluindo enfermeiros. Ele também contribuiu para conselhos consultivos de farmácia para o manejo de condições de baixa gravidade na comunidade.
Sobre o revisor

Sid Dajani
Sultan Dajani se formou na Escola de Farmácia de Londres em 1994 e se tornou o membro mais jovem eleito para o conselho da Sociedade Real de Farmácia desde sua fundação em 1842.
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
Artigo também disponível em Inglês, Alemão, Espanhol, Francês, Italiano, Português, Hindi, Hebraico, Árabe, e Sueco.
Próxima revisão prevista para: 17 Nov 2027
18 de maio de 2023 | Última versão

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