About agomelatine

Agomelatine is an atypical antidepressant used to treat depressão.

Depression is common and symptoms can affect day-to-day life and can become very distressing. Treatments include talking (psychological) treatments and antidepressant medicines.

Our bodies follow a daily cycle, called circadian rhythms, which control sleep and other functions. When these rhythms are disrupted, it can lead to depression. Agomelatine helps depression by restoring this natural balance.

The most common side effects of agomelatine are:

• Sentindo-se mal.

• Diarreia.

• Sentindo-se tonto, cansado ou sonolento.

• Dor de cabeça

• Constipação.

• Dor de estômago.

• Dificuldade para dormir.

• Sentindo-se ansioso.

• Increased sweating.

• Dor nas costas.

Você encontrará uma lista completa na bula fornecida com o seu medicamento. Os efeitos indesejados geralmente melhoram à medida que seu corpo se ajusta ao novo medicamento, mas fale com seu médico ou farmacêutico se algum dos seguintes persistir ou se tornar problemático.

Se você sentir quaisquer outros sintomas que acha que podem ser causados pelos comprimidos, fale com seu médico ou farmacêutico para mais orientações.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking agomelatine it is important that your doctor knows:

• Se você tem menos de 18 anos ou mais de 75 anos de idade.

• Se você está grávida ou amamentando.

• Se você tiver algum problema com o funcionamento do seu fígado, ou se tiver algum problema com o funcionamento dos seus rins.

• If you have ever had abnormally 'high' moods or dementia.

• Se você consome grandes quantidades de álcool regularmente.

• Se você estiver tomando outros medicamentos. Isso inclui quaisquer medicamentos que estejam disponíveis para compra sem receita médica, bem como medicamentos fitoterápicos e complementares.

• Se você já teve uma reação alérgica a um medicamento.

• Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about agomelatine, and will also provide you with a full list of the side effects which you could experience from taking it.

• Take agomelatine exactly as your doctor tells you to. The usual dose is one tablet daily. This may be increased in some people to two tablets daily (taken together) after a couple of weeks.

• You should take the tablets at bedtime. The tablets can be taken either with or without food.

• If you forget to take a dose, do not worry, just take the next dose when it is due.
  

• It can take a week or two after starting the tablets before the effect begins to build up, and maybe a few weeks longer before you feel the full benefit from the treatment. Do not stop taking agomelatine after a few days, thinking it is not helping.

• Try to keep your regular appointments with your doctor. This is because your doctor will want you to have a blood test every few weeks to check that your liver is staying healthy.

  • Your doctor will also give you a booklet to read which explains about what symptoms to look out for as signs that the medicine could be harming your liver. There is a list of these symptoms in the section below on the problems which can be caused by agomelatine.

• While you feel depressed or are taking agomelatine, you may have thoughts about harming yourself or ending your life. It is very important that you tell your doctor about this straightaway if it happens to you.

• Taking agomelatine and alcohol is not recommended, so do not drink alcohol during your treatment with this medicine.

• Smoking can affect the amount of agomelatine in your body. Let your doctor know if you either start or stop smoking while you are taking agomelatine.

• Your doctor will ask you to carry on taking agomelatine for a while after you feel better. This is to stop your symptoms from returning.

• There are several types of antidepressants and they differ in their possible side effects. If you find that agomelatine does not suit you then let your doctor know, as another could be found that will suit you.

• Mantenha todos os medicamentos fora do alcance e da vista das crianças.

• Armazene em local fresco e seco, longe de calor e luz diretos.
  

Is agomelatine a strong antidepressant?

Agomelatine is not considered a “strong” antidepressant in the traditional sense, but it can be effective for some people. It works differently to many other antidepressants, helping regulate sleep as well as mood.

Does agomelatine cause weight gain?

Agomelatine is less likely to cause weight gain than many other antidepressants. While changes in weight can happen for some people, they are not usually common side effects.

What class of drug is agomelatine?

Agomelatine belongs to a class of antidepressants known as melatonergic antidepressants. It works differently from SSRIs and SNRIs by acting on melatonin and serotonin receptors, which may help improve sleep patterns as well as mood.