Can I take Sertraline and Ibuprofen together?

It is generally recommended that you do not take sertralina e ibuprofeno together as they increases your risk of internal bleeding.

Por que isso acontece

Sertraline (an SSRI) reduces the amount of serotonin in your blood platelets, which are the cells responsible for clotting. Ibuprofen (an NSAID) also interferes with platelet function and can damage the protective lining of the stomach. When used together, these two effects combine to significantly raise the risk of a bleed.

• Speak to your doctor or pharmacist before taking these together.

• If you need pain relief, paracetamol is usually a safer choice while taking sertraline.

• If your doctor confirms you must take both, take them with food to protect your stomach.

• Seek medical help immediately if you notice signs of bleeding, such as vomit that looks like coffee grounds, very dark or tarry poo (stools), or unexplained bruising.

Stomach ulcers and bleeding

Taking these medicines together significantly increases your risk of serious stomach bleeding. Contact your doctor immediately if you notice black, tarry stools or vomit that looks like coffee grounds.

Asma

Do not take ibuprofen if you have asthma that is worsened by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can trigger a severe, life-threatening asthma attack.

Low sodium levels (hyponatraemia)

Sertraline can cause a dangerous drop in blood sodium levels, especially in the elderly. Seek medical help if you experience persistent confusion, muscle weakness, or seizures.

Gravidez (terceiro trimestre)

Não tome ibuprofeno se estiver grávida de mais de 6 meses, pois pode causar problemas graves no coração e nos rins do bebê e complicações durante o parto.

Álcool

It is best to avoid drinking alcohol while taking sertraline. Alcohol can increase the sedative effects of the medicine, making you feel more sleepy, dizzy, or unsteady. It can also worsen the symptoms of depression or anxiety.

It is best to avoid or strictly limit alcohol while taking ibuprofen. Combining alcohol with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen increases the risk of irritation to your stomach lining and can lead to stomach ulcers or bleeding.

Suco de toranja

Você deve evitar consumir grandes quantidades de suco de toranja enquanto estiver tomando sertralina. A toranja pode aumentar o nível de sertralina no seu sangue, o que pode aumentar o risco de efeitos colaterais.

Cafeína (Café, Chá, Bebidas Energéticas)

Sertraline can sometimes make you feel restless or shaky. High amounts of caffeine can worsen these side effects or increase feelings of anxiety.

Alimentos

Ibuprofen should ideally be taken with food or a glass of milk. This helps to protect your stomach lining and reduces the risk of indigestion or stomach ache.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.