Can I take Sertraline and Citalopram together?

It is generally not recommended that you take sertralina e citalopram together as they are the same class of SSRI (antidepressivo) and work in the same way to increase serotonin levels.

Taking them together creates an 'additive effect' where the levels become dangerously high, increasing the risk of síndrome serotoninérgica. Additionally, both drugs can affect the electrical activity of the heart in a similar way.

You should not take these two medicines together unless specifically instructed and closely monitored by a specialist.

Como saber se você está tendo uma interação medicamentosa

You may be experiencing a drug interaction between sertraline and citalopram if you notice:

• Agitation, restlessness or confusion.

• Shivering or sweating.

• Muscle twitching, stiffness or jerking movements.

• Fast heartbeat.

• Diarreia.

• Dor de cabeça.

• Feeling unusually anxious or overactive.

These may be signs of síndrome serotoninérgica, which can be serious.

Seek urgent medical help if you have:

• A high fever.

• Severe confusion or agitation.

• Convulsões.

• Irregular heartbeat.

• Perda de consciência.

If you are currently taking both, do not stop taking them suddenly, but contact your doctor immediately to discuss a safe plan.

Depression and anxiety disorders

These medicines can cause an increase in suicidal thoughts or the urge to self-harm, particularly in the first few weeks of treatment or when the dose is changed. Monitor your mood closely.

Síndrome da Serotonina

Combining these with other medicines that affect serotonin (such as St John’s Wort, tramadol, or triptans) can cause a life-threatening reaction involving high fever, agitation, and muscle stiffness.

Distúrbios de sangramento

These medicines can increase your risk of bleeding, especially in the stomach. Use with caution if you take aspirin, ibuprofen (NSAIDs), or blood-thinning medicines like warfarin.

Heart rhythm disorders (QT prolongation)

Citalopram can affect the electrical rhythm of your heart. It must be avoided if you have a pre-existing heart rhythm problem or are taking other medicines that affect the heart rate.

Níveis baixos de sódio (Hiponatremia)

Citalopram can cause a serious drop in blood sodium levels, especially in the elderly. Seek medical help if you experience extreme tiredness, confusion, or muscle twitching.

Álcool

It is best to avoid or strictly limit alcohol while taking these medicines. Alcohol can increase the drowsiness and dizziness caused by the medication, and may also make your symptoms of depression or anxiety worse.

Suco de toranja

You should avoid drinking large amounts of grapefruit juice while taking sertraline. Grapefruit can increase the level of sertraline in your blood, which may increase the risk of side effects.

Cafeína (Café, Chá, Bebidas Energéticas)

Citalopram can sometimes cause feelings of restlessness or jitteriness, especially when you first start taking it. Caffeine is a stimulant that can worsen these side effects and may increase feelings of anxiety. It is advisable to monitor your caffeine intake.

Tomando vários medicamentos? Nosso Verificador de Interações de Medicamentos ajuda você a verificar se suas prescrições, medicamentos de venda livre e suplementos são seguros para serem tomados juntos. Basta procurar seus medicamentos para ver possíveis interações e o que fazer sobre elas.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.