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Can I take Ibuprofen and Naproxen together?

Guia de interação medicamentosa

Taking ibuprofen and naproxen together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. It can also make your blood pressure rise and cause fluid retention.

Não tome ibuprofeno e naproxeno at the same time. If one is not managing your pain, speak to a pharmacist or doctor about adding a different type of painkiller, such as paracetamol, which works differently and is generally safe to take alongside one NSAID.

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Por que isso acontece

Both ibuprofen and naproxen belong to the same family of medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). They work by blocking the same enzymes in the body.

Taking both is like taking a double dose of the same type of medicine; it doesn't provide better pain relief but it does double the strain on your stomach lining and kidneys.

You may be experiencing an interaction between ibuprofen and naproxen if:

  • You took ibuprofen and naproxen together or close in time.

  • You have black, tarry, or bloody poo (stools).

  • You have stomach pain, heartburn, or feeling sick (nausea).

  • You feel dizzy or very tired.

  • You notice swelling, shortness of breath, or chest pain,

  • You pee less than usual or have swollen ankles/legs.

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Se você tiver algum dos sintomas acima, você deve:

  • Stop taking ibuprofen and naproxen (don’t mix them).

  • Use paracetamol instead for pain, unless a doctor says otherwise.

  • Get urgent help for chest pain, breathing problems, severe stomach pain, or vomiting blood/black stools.

  • Contact a GP or pharmacist if symptoms are mild but don’t go away.

  • Drink water and avoid alcohol while you recover.

Asma

Do not take these medicines if you have asthma, as they can trigger a severe or life-threatening asthma attack (bronchospasm).

Úlceras estomacais ou sangramento

Avoid these medicines if you have ever had a stomach ulcer or gastrointestinal bleeding, as they significantly increase the risk of serious internal bleeding and perforation.

Gravidez (terceiro trimestre)

Do not take these medicines if you are more than 28 weeks pregnant, as they can cause serious heart and kidney problems in the unborn baby and complications during birth.

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Álcool

Drinking alcohol while taking NSAIDs like ibuprofen or naproxen can increase the risk of stomach irritation, stomach ulcers, and gastrointestinal bleeding. It is best to limit alcohol intake or avoid it entirely if you have a history of stomach issues.

Alimentação (Geral)

While not an interaction that changes how the drug works, you should ideally take these medicines with or just after food or a snack. This helps to protect your stomach lining and reduces the risk of indigestion or stomach pain.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.

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Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • 24 Jan 2026 | Publicado originalmente
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