Can I take Hydroxocobalamin and Sukkarto together?
Guia de interação medicamentosa
Publicado originalmente 25 Jan 2026
Atende aos diretrizes editoriais
- BaixarBaixar
- Compartilhar
- Language
- Discussão
- Versão em Áudio
- Add to preferred sources on Google
Sukkarto (metformin) can lower the levels of Vitamin B12 (hydroxocobalamin) in your body over time. While hydroxocobalamin is used to treat B12 deficiency, taking Sukkarto may make it harder for your body to maintain healthy levels, potentially requiring more frequent monitoring or higher doses of the vitamin.
Neste artigo:
Video picks for Interações medicamentosas
Continue lendo abaixo
Por que isso acontece
Sukkarto (metformin) interferes with the way the digestive system absorbs Vitamin B12 from food and supplements. It can also affect how the body moves B12 into the blood. Since you are taking hydroxocobalamin to replace or boost your B12 levels, the Sukkarto may work against this by reducing how much of the vitamin your body can actually use.
O que você deve fazer
Voltar ao conteúdoYou can take these medicines together, but you should inform your doctor. They may want to perform regular blood tests to check your Vitamin B12 levels, especially if you have been taking Sukkarto for a long time. If you feel unusually tired, have a sore tongue, or feel 'pins and needles' in your hands or feet, tell your doctor as these can be signs of low B12.
Continue lendo abaixo
Precauções importantes
Voltar ao conteúdoProblemas graves nos rins ou no fígado
You must not take Sukkarto if you have severe kidney or liver failure, as it significantly increases the risk of a rare but life-threatening condition called lactic acidosis.
Dehydration or severe infection
Stop taking Sukkarto and seek medical advice immediately if you develop severe vomiting, diarrhoea, or a high fever. These can lead to dehydration, which increases the risk of serious kidney problems while on this medicine.
X-ray or scan using iodine contrast dye
You must stop taking Sukkarto before and for 48 hours after having an X-ray or scan involving an injection of 'contrast dye', as the combination can cause acute kidney failure.
Hypokalaemia (low potassium)
When starting treatment for severe vitamin B12 deficiency, your potassium levels can drop rapidly as your body produces new red blood cells. This can be dangerous for your heart and may require monitoring by your doctor.
Avisos sobre alimentos e bebidas
Voltar ao conteúdoÁlcool
It is best to avoid or strictly limit alcohol while taking Sukkarto. Combining alcohol with metformin increases the risk of a rare but very serious condition called lactic acidosis (a build-up of acid in the blood). It can also increase the risk of low blood sugar (hypoglycaemia).
It is best to avoid or strictly limit alcohol while receiving hydroxocobalamin treatment. Excessive alcohol consumption can interfere with the absorption of Vitamin B12 and may worsen the underlying deficiency being treated. Combining alcohol with medication also increases the risk of liver strain.
Ingestão Geral de Alimentos
Sukkarto should be taken with or immediately after a meal. This helps to reduce common side effects such as nausea, vomiting, stomach ache, and diarrhoea.
Continue lendo abaixo
Usando outros medicamentos
Voltar ao conteúdoTaking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Aviso Legal
Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.
Patient picks for Interações medicamentosas

Verificador de interações medicamentosas
Posso tomar Losartana e Vitamina D juntos?
Não há interação direta conhecida entre losartana e suplementos de vitamina D. Tomar os dois juntos é geralmente considerado seguro.

Verificador de interações medicamentosas
Can I take Sertraline and Fluoxetine together?
Taking sertraline and fluoxetine together significantly increases the risk of a rare but serious condition called serotonin syndrome. This happens because both medicines work by increasing the level of a chemical called serotonin in your brain. If levels get too high, it can cause symptoms like shivering, diarrhoea, confusion, severe muscle tightness, fever, and even seizures. Additionally, fluoxetine can slow down how your body breaks down sertraline, leading to a build-up of the drug in your system and increasing the risk of side effects.
Continue lendo abaixo
Histórico do artigo
As informações nesta página são escritas e revisadas por clínicos qualificados.
25 Jan 2026 | Publicado originalmente

Pergunte, compartilhe, conecte-se.
Navegue por discussões, faça perguntas e compartilhe experiências em centenas de tópicos de saúde.

Sentindo-se mal?
Avalie seus sintomas online gratuitamente
Inscreva-se no boletim informativo do Patient
Sua dose semanal de conselhos de saúde claros e confiáveis - escritos para ajudá-lo a se sentir informado, confiante e no controle.
By subscribing you accept our Política de Privacidade. Você pode cancelar a inscrição a qualquer momento. Nunca vendemos seus dados.