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Can I take Evening primrose oil and Vitamin C together?

Guia de interação medicamentosa

There are no known significant interactions between evening primrose oil and vitamin C. It is generally considered safe to take these two supplements together.

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Por que isso acontece

Evening primrose oil is a source of omega-6 fatty acids (specifically gamma-linolenic acid), while vitamin C is a water-soluble antioxidant. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness. In fact, some evidence suggests that antioxidants like vitamin C may help protect the fatty acids in evening primrose oil from oxidising (breaking down) in the body.

You can continue to take both supplements as directed. As with any supplement, it is best to take them with food to reduce the chance of an upset stomach. If you have any underlying health conditions or are taking prescribed medications (especially blood thinners or epilepsy medication), consult your pharmacist or doctor before starting new supplements.

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Epilepsy or Schizophrenia

Evening primrose oil may increase the risk of seizures, particularly in people with a history of epilepsy or those taking phenothiazine medications for schizophrenia.

Distúrbios de coagulação ou cirurgia próxima

Evening primrose oil can thin the blood and increase the risk of bruising or bleeding. You must stop taking it at least two weeks before any scheduled surgery.

Kidney stones or kidney disease

High doses of vitamin C can increase the amount of oxalate in your urine, significantly raising the risk of developing kidney stones.

G6PD deficiency

If you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, high doses of vitamin C can cause your red blood cells to break down (haemolysis).

Hemocromatose

Vitamin C increases the absorption of iron from your food. If you have an iron-overload disorder like haemochromatosis, you should avoid high-dose supplements.

Álcool

It is best to avoid or strictly limit alcohol when taking evening primrose oil. While there is no direct chemical interaction, both substances can lower the seizure threshold in susceptible individuals, and alcohol may worsen the side effects of the supplement, such as nausea or indigestion.

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Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.

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Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • 25 Jan 2026 | Publicado originalmente
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