Can I take Apixaban and Ibuprofen together?

You should avoid taking ibuprofeno while you are on apixabana unless specifically instructed to do so by your doctor as taking them together can significantly increases your risk of serious bleeding.

If you need pain relief, paracetamol is generally a safer alternative.

Por que isso acontece

Both medicines affect how your blood clots, but in different ways. Apixaban is an anticoagulant (blood thinner) that interferes with clotting proteins. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that prevents platelets (tiny blood cells) from sticking together.

When used together, they have an 'additive' effect, making the blood much thinner than intended. Additionally, ibuprofen can irritate the lining of the stomach, making stomach ulcers and bleeding more likely.

You may be experiencing an interaction between apixaban and ibuprofen if:

• You notice unusual bruising or bleeding, such as nosebleeds, bleeding gums, or easy bruising.

• You have blood in your urine or stools, or black, tarry stools.

• You experience severe or persistent headaches, dizziness, or lightheadedness.

• You develop stomach pain, indigestion, or ulcers.

• You feel unusually tired or weak without a clear reason.

• Symptoms appear soon after starting or increasing the dose of ibuprofen while taking apixaban.
  

Se você tiver algum dos sintomas acima, você deve:

• Seek urgent medical advice or contact your GP immediately.

• Do not stop taking apixaban unless instructed by a healthcare professional.

• Avoid taking ibuprofen or other AINEs until you have spoken to a doctor or pharmacist.

• Informe o seu profissional de saúde sobre todos os medicamentos e suplementos que você está tomando.

• Attend any blood tests or check-ups recommended to monitor bleeding risk.

Asma

Não tome ibuprofeno se você tiver asma que piora com aspirina ou outros anti-inflamatórios não esteroides (AINEs), pois isso pode desencadear uma crise de asma potencialmente fatal.

Cirurgia de emergência ou ferimento

Always carry your anticoagulant alert card. In the event of a serious injury or emergency surgery, healthcare staff must know you are on apixaban because your blood will not clot normally.

Álcool

Drinking alcohol while taking these medicines can increase the risk of bleeding in your stomach. It is best to limit your alcohol intake or avoid it altogether. If you do drink, keep to the recommended low-risk limits (no more than 14 units a week).

Food (general)

You should ideally take ibuprofen with food or a glass of milk. This helps to protect your stomach lining and reduces the risk of indigestion or stomach irritation.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.