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Can I take Alogliptin and Metformin together?

Guia de interação medicamentosa

Taking alogliptin and metformin together is generally safe and very common. However, because both medicines work to lower your blood sugar, there is a slightly higher risk of your blood sugar dropping too low (hypoglycaemia). This is more likely if you are also taking other diabetes medicines like insulin or a sulphonylurea.

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Por que isso acontece

Both drugs work in different ways to lower blood glucose. Alogliptin helps the body release more insulin after eating, while metformin reduces the amount of sugar the liver produces and helps the body use its own insulin better. Together, they have an 'additive' effect, meaning they work as a team to control blood sugar more effectively than either drug alone.

You should continue taking both medicines as prescribed by your doctor. It is important to learn the signs of low blood sugar (such as feeling shaky, sweaty, hungry, or dizzy) and always carry a fast-acting sugar source, like glucose tablets or a sugary drink. If you frequently experience symptoms of low blood sugar, speak to your doctor as they may need to adjust your doses.

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Acidose láctica

Stop taking metformin and seek urgent medical help if you experience severe vomiting, diarrhoea, or dehydration. This medicine can cause a rare but life-threatening build-up of acid in the blood if you become severely unwell or have kidney problems.

Pancreatite

Stop taking alogliptina and see a doctor immediately if you develop severe and persistent stomach pain, which may reach through to your back. This can be a sign of an inflamed pancreas.

Contrast X-rays/Scans

You must tell your doctor you take metformin if you are having an X-ray or scan involving an injection of 'contrast' dye. You will need to stop taking metformin for 48 hours to prevent sudden kidney damage.

Álcool

Drinking alcohol while taking metformin can increase the risk of a rare but serious condition called lactic acidosis. It can also cause your blood sugar levels to drop too low (hypoglycaemia). You should avoid excessive alcohol consumption and binge drinking.

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Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.

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Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • 25 Jan 2026 | Publicado originalmente
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