lipase C, hepatic type
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A LIPC gene provides instructions for making an enzyme called hepatic lipase. This enzyme is produced by liver cells and released into the bloodstream where it helps with the conversion of fat-transporting molecules called very low-density lipoproteins (VLDLs) and intermediate-density lipoproteins (IDLs) to low-density lipoproteins (LDLs). The enzyme also assists in transporting molecules called high-density lipoproteins (HDLs) that carry cholesterol and triglycerides from the blood to the liver, where the HDLs deposit these fats so they can be redistributed to other tissues or removed from the body. Hepatic lipase helps to keep these fat-transporting molecules in balance by regulating the formation of LDLs and the transport of HDLs. Normally, high levels of HDL (known as "good cholesterol") and low levels of LDL (known as "bad cholesterol") are protective against heart disease.
Normal function
A LIPC gene provides instructions for making an enzyme called hepatic lipase. This enzyme is produced by liver cells and released into the bloodstream where it helps with the conversion of fat-transporting molecules called very low-density lipoproteins (VLDLs) and intermediate-density lipoproteins (IDLs) to low-density lipoproteins (LDLs). The enzyme also assists in transporting molecules called high-density lipoproteins (HDLs) that carry cholesterol and triglycerides from the blood to the liver, where the HDLs deposit these fats so they can be redistributed to other tissues or removed from the body. Hepatic lipase helps to keep these fat-transporting molecules in balance by regulating the formation of LDLs and the transport of HDLs. Normally, high levels of HDL (known as "good cholesterol") and low levels of LDL (known as "bad cholesterol") are protective against heart disease.
Conditions referring to this gene or chromosome
Other names
HDLCQ12
hepatic lipase
HL
HTGL
lipase C, hepatic
lipase member C
lipase, hepatic
LIPH
Related patient information and medicines
Patient information leaflet
Pancreatite aguda
Anyone with suspected acute pancreatitis will be admitted to hospital for tests to rule out other problems (as many conditions can cause similar symptoms) and to confirm the diagnosis. Blood tests can check the blood level of amylase e/ou lipase (these são digestive enzymes made by the pancreas). Although not 100% reliable, a high blood level of.
Patient information leaflet
Distúrbios de armazenamento de glicogênio
Distúrbios de armazenamento de glicogênio are a group of inherited diseases. They result from a problem with one of the proteins (known as enzymes) involved in the conversion of glucose to glycogen, or the breakdown of glycogen back into glucose. They mostly tend to affect your liver and muscles. Most are diagnosed in childhood. Symptoms include weakness,.
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Câncer primário de fígado
Many types of cancer can spread to the liver - most commonly, cancers of the bowel , pancreas , stomach , lung or breast. The behaviour, treatment and outlook of secondary liver cancers are often quite different to those of primary liver cancer. Hepatocellular carcinoma. This is the most common type. It occurs in about 9 out of 10 cases. This type.
Patient information leaflet
Insuficiência hepática
Aguda liver failure is life-threatening and needs emergency medical care. Liver failure often develops slowly over many years. There are many causes of acute liver failure. These include paracetamol poisoning, infections (for example, hepatite B ou hepatitis C), acute fatty liver of pregnancy and a number of rare genetic conditions. For some.
Patient information leaflet
Posso tomar Pancreatina e Lixiana juntos?
There are no known ... Pancreatin works locally in the gut to help digest food, while Lixiana is absorbed into the bloodstream to prevent blood clots. Why this happens Pancreatin consists of digestive enzymes (lipase, protease, and amylase) that break down fats, proteins, and starches in the digestive tract. Lixiana is an oral anticoagulant (blood.
Patient information leaflet
Cirrose
However, as the function of the liver gradually becomes worse, serious problems can develop. In the UK, the two commonest causes of cirrhosis are alcohol drinking above recommended limits and hepatitis C infection. Treatments may vary, depending on the cause. Hepatite C e cirrose Persistent (chronic) infection with the hepatite C virus.
Leitura adicional e referências
- lipase C, hepatic type; MedlinePlus, National Library of Medicine.
- Chatterjee C, Sparks DL. Hepatic lipase, high density lipoproteins, and hypertriglyceridemia. Am J Pathol. 2011 Apr;178(4):1429-33. doi: 10.1016/j.ajpath.2010.12.050. Epub 2011 Feb 26.
- Kobayashi J, Miyashita K, Nakajima K, Mabuchi H. Hepatic Lipase: a Comprehensive View of its Role on Plasma Lipid and Lipoprotein Metabolism. J Atheroscler Thromb. 2015;22(10):1001-11. doi: 10.5551/jat.31617. Epub 2015 Jul 21.
- Tilly-Kiesi M, Schaefer EJ, Knudsen P, Welty FK, Dolnikowski GG, Taskinen MR, Lichtenstein AH. Lipoprotein metabolism in subjects with hepatic lipase deficiency. Metabolism. 2004 Apr;53(4):520-5. doi: 10.1016/j.metabol.2003.10.020.
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