Can I take Stexerol D3 and Sukkarto together?

Why this happens

Stexerol D3 (Vitamin D3) and Sukkarto (Metformin) are processed by the body through different pathways. Stexerol D3 is a fat-soluble vitamin that helps with calcium absorption, while Sukkarto works primarily in the liver and gut to improve insulin sensitivity. They do not interfere with how each other is absorbed, broken down, or removed from the body.

What you should do

You can continue to take both medicines as prescribed by your doctor. It is often recommended to take Sukkarto with or after a meal to reduce stomach-related side effects. Stexerol D3 is also best absorbed when taken with a meal containing some fat.

Important precautions

Lactic Acidosis

Stop taking Sukkarto and seek urgent medical help if you experience vomiting, stomach ache, muscle cramps, or a general feeling of being very unwell with severe tiredness. This may be a sign of lactic acidosis, a rare but serious complication, especially if you have kidney problems or drink excessive alcohol.

Severe Dehydration

Stop taking Sukkarto temporarily if you have a condition that may lead to severe dehydration, such as severe vomiting, diarrhoea, fever, or reduced fluid intake. This helps prevent serious kidney issues.

Hypercalcaemia (High blood calcium)

You must not take Stexerol D3 if you have high levels of calcium in your blood or urine, or if you have severe kidney stones, as it can dangerously worsen these conditions.

Contrast X-rays/Scans

You must tell your doctor you take Sukkarto if you are having an X-ray or scan involving an injection of 'contrast' dye. You will need to stop taking your tablets before the procedure and for 48 hours afterwards to protect your kidneys.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol while taking Sukkarto. Combining alcohol with metformin increases the risk of a rare but serious condition called lactic acidosis (a build-up of lactic acid in the blood). It also increases the risk of low blood sugar (hypoglycaemia).

It is best to avoid or strictly limit alcohol while taking Stexerol D3. Long-term heavy alcohol use can interfere with how your body processes Vitamin D and may weaken your bones.

Vitamin B12 absorption

While not a direct food interaction, long-term use of Sukkarto can lower your Vitamin B12 levels. You should ensure your diet includes B12-rich foods (like meat, dairy, or eggs) or speak to your doctor about monitoring your levels.

General Food Intake

Sukkarto should be taken with or immediately after a meal. This helps to reduce common side effects such as nausea, vomiting, stomach ache, and diarrhoea.

High-calcium foods (e.g. dairy products, fortified cereals)

Stexerol D3 helps your body absorb calcium. If you consume very high amounts of calcium through your diet while taking high-dose Vitamin D, it can lead to 'hypercalcaemia' (too much calcium in the blood). This can cause nausea, vomiting, and kidney problems. Your doctor may monitor your calcium levels.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.