Can I take Lansoprazole and Clopidogrel together?

It is generally not recommended to take lansoprazol e clopidogrel together as lansoprazole can reduce how well clopidogrel works, making it less effective at preventing blood clots.

Clopidogrel needs to be changed into its active form by an enzyme in the liver (called CYP2C19) to work properly. Lansoprazole can interfere with this enzyme, meaning less of the clopidogrel is converted into its active 'blood-thinning' form.

You should speak to your doctor or pharmacist before taking these together. They may suggest an alternative stomach acid medicine, such as pantoprazole ou famotidine, which are less likely to interfere with clopidogrel.

Como saber se você está tendo uma interação medicamentosa

You may be experiencing an interaction between lansoprazole and clopidogrel if you notice:

• Dor ou pressão no peito.

• Falta de ar.

• Weakness, numbness, or trouble speaking.

• Unexplained blood clots or stroke-like symptoms.

• Changes in bleeding patterns (less than expected).

If you notice these symptoms:

• Call emergency services immediately for chest pain, shortness of breath, or stroke-like signs.

• Do not stop your medications on your own.

• Contact your doctor as soon as possible.

• Keep a record of your symptoms and medications.

Drug Interaction

Lansoprazole can make clopidogrel less effective, increasing your risk of a heart attack or stroke. Your doctor may suggest a different stomach medicine, such as famotidine, instead.

Bleeding Risk

You must tell any surgeon or dentist that you are taking clopidogrel before any procedure is planned, as it increases the risk of serious bleeding and may need to be stopped 7 days in advance.

Diarreia grave

O Lansoprazol pode aumentar o risco de infecções intestinais graves. Se você desenvolver diarreia aquosa severa ou persistente, ou febre, entre em contato com seu médico imediatamente e não tome medicamentos antidiarreicos.

Lúpus (LES) ou reações cutâneas

Consulte seu médico se desenvolver uma erupção cutânea, especialmente em áreas expostas ao sol, pois o lansoprazol pode causar uma reação autoimune rara, mas grave, na pele.

Suco de toranja

Avoid drinking large amounts of grapefruit juice. Grapefruit contains compounds that can reduce the effectiveness of clopidogrel, potentially making it less effective at preventing blood clots.

Álcool

While alcohol does not directly interact with lansoprazole, it is best to limit or avoid it. Alcohol can increase stomach acid production and irritate the digestive system, which may worsen the symptoms your medicine is trying to treat.

It is best to avoid or strictly limit alcohol while taking clopidogrel. Both alcohol and clopidogrel can irritate the stomach lining and increase the risk of internal bleeding, particularly in the stomach and intestines.

Caffeine (coffee, tea, cola)

Caffeine can trigger or worsen symptoms of acid reflux and stomach ulcers. If you are taking lansoprazole for these conditions, reducing your caffeine intake may help the medicine work more effectively.

Alimentação (Horário)

O Lansoprazol funciona melhor se tomado pelo menos 30 minutos antes das refeições. Tomá-lo com ou após a comida pode reduzir sua eficácia na diminuição do ácido estomacal.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.