Can I take Danazol and Tramadol together?

Por que isso acontece

Tramadol is broken down in the liver by specific enzymes. Danazol blocks these enzymes, preventing the body from clearing the tramadol. This leads to a build-up of the painkiller to potentially toxic levels.

You should speak to your doctor before taking these two medicines together. Your doctor may need to adjust your dose of tramadol or monitor you more closely for side effects. If you feel unusually dizzy, sleepy, or have trouble breathing, seek medical help immediately.

Gravidez

You must not take danazol if you are pregnant or planning to become pregnant. It can cause the development of male physical characteristics in a female foetus. You must use effective, non-hormonal contraception (such as condoms) while taking it.

Blood clots (Thromboembolism)

Danazol significantly increases the risk of serious blood clots. Seek immediate medical help if you experience sudden leg swelling, chest pain, or shortness of breath.

Doença hepática

Danazol can cause serious liver damage and non-cancerous liver tumours. You will need regular blood tests to monitor your liver function while taking this medicine.

Epilepsy or history of seizures

Tramadol can increase the risk of having a fit (seizure), even at the recommended dose. This risk is higher if you already have epilepsy or are taking certain antidepressants.

Asthma or breathing problems

Tramadol can cause dangerous breathing difficulties (respiratory depression). You must not take it if you have severe asthma or significant breathing problems.

Álcool

It is best to avoid or strictly limit alcohol while taking danazol. Combining danazol with alcohol can cause you to feel nauseous or short of breath (a disulfiram-like reaction). Additionally, both danazol and alcohol can put strain on your liver, and using them together increases the risk of liver damage.

It is best to avoid or strictly limit alcohol while taking tramadol. Combining alcohol with tramadol significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness.

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Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.