Can I take Atorvastatin and Rivaroxaban together?

Por que isso acontece

Both medications are processed by the same enzyme system in the liver (CYP3A4) and a transport protein (P-gp). Because they compete for these systems, atorvastatin can slow down the breakdown of rivaroxaban, leading to slightly higher levels of the blood thinner in your body.

It is generally safe to take these two medicines together, as the interaction is usually mild. However, you should be vigilant for any signs of unusual bleeding or bruising. If you notice blood in your urine, black tarry stools, or a nosebleed that won't stop, contact your doctor immediately. Ensure your doctor knows you are taking both, especially if your dose of atorvastatin is increased.

Gravidez

Você não deve tomar atorvastatina se estiver grávida ou planejando engravidar, pois pode causar danos graves ao bebê. Use contracepção eficaz enquanto estiver tomando este medicamento.

Muscle disorders - atorvastatin

Procure aconselhamento médico imediato se você sentir dor muscular inexplicada, sensibilidade ou fraqueza. Em casos raros, isso pode levar a uma condição séria chamada rabdomiólise, que causa danos aos rins.

Active bleeding or high bleeding risk

Rivaroxaban significantly increases your risk of serious bleeding. You must seek immediate medical help if you have a fall or head injury, or if you notice signs of internal bleeding such as black tarry stools or coughing up blood.

Suco de toranja

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Álcool

While there is no direct interaction, drinking large amounts of alcohol can increase the risk of liver problems with atorvastatin and increase the risk of stomach bleeding with rivaroxaban. It is best to stick to the recommended daily limits.

Food (General) - rivaroxabana

The 15mg and 20mg tablets must be taken with food to ensure the medicine is absorbed properly into your body. If taken on an empty stomach, the medicine may not work as well. The 2.5mg and 10mg doses can be taken with or without food.

Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.