Can I take Atorvastatin and Omeprazole together?

It is generally considered safe to take atorvastatin e omeprazole together, but with caution, as omeprazole may increase blood levels of atorvastatin.

It is often helpful to take your atorvastatin at the same time each day to maintain steady levels in your body.

Por que isso acontece

Omeprazole can affect the way the body breaks down atorvastatin by interfering with certain enzymes in the liver (CYP3A4) and transport proteins. It also changes the acidity of the stomach, which can slightly alter how much of the statin is absorbed into the bloodstream.

You may be experiencing an interaction between atorvastatin and omeprazole if:

• You develop new or worsening muscle pain, tenderness, or weakness.

• You feel unusually tired or weak without a clear reason.

• You notice dark-coloured pee (urine).

• You experience unexplained muscle cramps.

• Blood tests show raised muscle enzymes (CK levels) or changes in liver function.

• Symptoms start soon after starting or changing the dose of either medicine.

Serious interactions are uncommon, but always speak to a doctor or pharmacist if you notice new or worrying symptoms while taking both medicines.

Se você tiver algum dos sintomas acima, você deve:

• Contact your GP or pharmacist for advice as soon as possible.

• Do not stop taking your medicines suddenly unless advised by a healthcare professional

• Seek urgent medical help if muscle pain is severe, widespread, or worsening

• Get medical advice immediately if you notice dark urine or severe weakness

• Tell your healthcare professional about all medicines and supplements you are taking

• Attend any blood tests arranged to check muscle or liver health

Gravidez

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can harm the developing baby. Use effective contraception while taking it.

Muscle pain or weakness - atorvastatin

Report any unexplained muscle pain, tenderness, or weakness to your doctor immediately. In rare cases, this can lead to serious kidney problems.

Severe or persistent diarrhoea

Contact your doctor if you develop severe or watery diarrhoea that does not stop, as omeprazole can increase the risk of a serious bowel infection called C. difficile.

Suco de toranja

Grapefruit juice can increase the level of atorvastatin in your blood, which may increase the risk of side effects like muscle pain. Avoid drinking large amounts (more than 1.2 litres a day), though a small glass is usually fine.

Álcool

Drinking large amounts of alcohol while taking atorvastatin can increase the risk of liver problems. It is best to keep your intake within the recommended limits.

Tomando vários medicamentos? Nosso Verificador de Interações de Medicamentos ajuda você a verificar se suas prescrições, medicamentos de venda livre e suplementos são seguros para serem tomados juntos. Basta procurar seus medicamentos para ver possíveis interações e o que fazer sobre elas.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.