Can I take Atorvastatin and Fibre supplements together?

Why this happens

Fibre supplements (like psyllium husk or methylcellulose) can bind to the atorvastatin in your stomach or intestines, preventing it from entering your bloodstream.

What you should do

You do not need to stop taking fibre, but you should separate the doses. Take your atorvastatin at least 1 hour before or 4 hours after taking a fibre supplement.

Important precautions

Pregnancy

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

Drug absorption

Fibre supplements can prevent other medicines from being absorbed properly. Take your other medicines at least 1 hour before or 2 to 4 hours after taking fibre.

Food and drink warnings

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Alcohol

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).

Water/Fluids

It is essential to drink plenty of water (at least 200ml) when taking fibre supplements. Without enough fluid, the supplement can swell and block your throat or bowel.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.