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Can I take Amlodipine and Citalopram together?

Guia de interação medicamentosa

Taking amlodipine and citalopram together may increase the risk of developing an abnormal heart rhythm. While both are commonly prescribed together, they can both affect the electrical activity of your heart. In rare cases, this can lead to a serious condition called QT prolongation, where the heart muscle takes longer than normal to recharge between beats. This can cause palpitations, dizziness, or fainting.

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Por que isso acontece

Both medications have the potential to affect the 'QT interval' (the electrical timing of the heart). Citalopram is known to cause this effect, especially at higher doses, and amlodipine may occasionally contribute to this or change how the heart responds to electrical signals.

For most people, this combination is safe, but you should use caution. Ensure your doctor knows you are taking both. Seek medical help immediately if you feel a sudden fast or pounding heartbeat, severe dizziness, or if you faint. Your doctor may occasionally want to check your heart rhythm with an ECG (heart trace) or monitor your salt levels (electrolytes) through blood tests.

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Transtornos de depressão e ansiedade

You may experience an increase in suicidal thoughts or the urge to self-harm when first starting this medicine or changing the dose. This is more common in young adults under 25. Contact your doctor or go to hospital immediately if this happens.

Distúrbios do ritmo cardíaco (Síndrome do QT longo)

Do not take citalopram if you have a history of abnormal heart rhythms or are taking other medicines that affect heart rhythm, as it can cause a life-threatening heart rhythm change.

Severe aortic stenosis

Amlodipine can cause a dangerous drop in blood pressure if you have a severely narrowed heart valve (aortic stenosis).

Distúrbios de sangramento

Citalopram increases your risk of serious bleeding, especially if you are also taking aspirin, warfarin, or other blood-thinning medicines.

Níveis baixos de sódio (Hiponatremia)

Citalopram can cause a serious drop in blood sodium levels, especially in the elderly. Seek medical help if you experience extreme tiredness, confusion, or muscle twitching.

Álcool

Drinking alcohol while taking these medicines can make you feel more sleepy or dizzy. It is best to stop drinking alcohol or keep your intake to a minimum until you see how the medicines affect you.

Suco de toranja

Grapefruit juice can increase the concentration of amlodipine in your blood, which may make your blood pressure drop too low and increase the risk of side effects like headaches or swollen ankles. Avoid drinking large amounts of grapefruit juice while taking this medicine.

Cafeína (Café, Chá, Bebidas Energéticas)

Citalopram can sometimes cause feelings of restlessness or jitteriness, especially when you first start taking it. Caffeine is a stimulant that can worsen these side effects and may increase feelings of anxiety. It is advisable to monitor your caffeine intake.

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Taking multiple medicines? Our Verificador de Interações de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Aviso Legal

Esta informação é apenas para fins educacionais gerais e não deve ser considerada como um substituto para aconselhamento médico profissional. Sempre consulte seu médico, farmacêutico ou outro profissional de saúde qualificado antes de tomar decisões sobre seus medicamentos. As circunstâncias individuais podem variar, e somente um profissional de saúde que conheça seu histórico médico pode fornecer orientações personalizadas.

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Histórico do artigo

As informações nesta página são escritas e revisadas por clínicos qualificados.

  • 25 Jan 2026 | Publicado originalmente
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