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Medicamentos genéricos vs marcas comerciais

Todo medicamento tem um nome genérico aprovado. Se for fabricado por várias empresas, cada uma também dará ao medicamento um nome de marca (comercial). Assim, um medicamento pode ter um nome genérico e também ter um ou mais nomes de marca. Isso às vezes pode levar a confusão.

Em resumo

  • Generic medicines are drugs identified by their approved medical name.

  • Brand name medicines are specific versions of a drug made by a company.

  • The colour or shape of your medicine may change if a different company makes it.

  • Doctors often prescribe the generic name, which is usually cheaper for the NHS.

  • Most generic and brand-name versions of a medicine have the same quality and action.

  • Some medicines, like certain epilepsy drugs, are always prescribed by brand name.

  • If in doubt about a medicine, speak to your pharmacist.

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What are generic medicines?

Each medicine has an approved name called the generic name. A group of medicines that have similar actions often have similar-sounding generic names. For example, fenoximetilpenicilina, ampicillin, amoxicilina e flucloxacilina are in one group of antibióticos.

What are brand name medicines?

Many medicines also have one (or more) brand names. This is chosen by the company that makes it. Several companies may make the same generic medicine, each with their own brand name. The name is often chosen to be memorable for advertising, or to be easier to say or spell than the generic name. For example, paracetamol is a generic name. There are several companies that make this with brand names such as Panadol®, Calpol®, etc.

The brand name is usually written most clearly on any packaging. However, you will always see the generic name written somewhere on the packet (often in small print). Some medicines only have the generic name on the packet.

The colour, size, shape, etc, of brands of the same medicine may vary depending on which company makes it. Do not be alarmed if your regular medicine seems to have changed colour or shape. It may be that the pharmacist is getting it from a different company, or the doctor has written the prescription in a generic way rather than using a brand name. However, the medicine will be the same if the generic name is the same as before.

Produtos combinados

Some tablets or pills contain a combination of medicines. Combination products are often marketed and sold with a brand (trade) name. However, the individual ingredients (the individual medicines that are combined into the one tablet or pill) will all be listed in small print on the packet. For example, a popular painkiller has a brand name of Solpadol®. This contains two generic medicines - paracetamol and codeína. It can also be prescribed under its generic name of co-codamol.

Prescrição genérica

Doctors are encouraged to prescribe by using the name of the generic medicine. This is because:

  • The generic medicine name is the one doctors are trained to use. There are sometimes many brand (trade) names for one medicine. Possible confusion or mistakes are reduced if all doctors use the same names when talking about and prescribing medicines.

  • Generic medicines are often cheaper for the NHS. Even for medicines that you can buy, such as paracetamol, there is often a big price difference between brands.

  • If generic medicine is prescribed, a pharmacist can dispense any suitable (available) product to the patient. This cuts out the risk of delays in the patient receiving their treatment whilst waiting for a specific brand.

A few medicines, however, are always prescribed by the specific brand. This is because there are significant differences between the different brands in the amount you end up having in your body (bioavailability). Examples of these type of medicines are:

What about quality of medicines?

In the UK there are strict quality controls before a product licence is granted for brand (trade) named or generic versions of medicines. This means that a generic or brand name version of the same medicine will be of the same quality, and have the same action.

Check with your pharmacist if in doubt about the use of a medicine.

Perguntas frequentes

What is 'generic prescribing'?

Generic prescribing is when doctors write prescriptions using the official generic name of a medicine, rather than a specific brand name. This practice helps to reduce confusion, as all doctors use the same names for medicines. It also allows pharmacists to dispense any suitable and available product that contains the prescribed generic medicine, ensuring patients receive their treatment without delays. Furthermore, generic medicines are often more cost-effective for the NHS.

Why would my medicine's colour or shape change?

It is normal for the colour, size, or shape of your medicine to vary, even if it's the same medicine you usually take. This often happens because the pharmacist might be sourcing the medicine from a different company, or your doctor may have prescribed it using its generic name rather than a specific brand. As long as the generic name on the packaging remains the same, you can be assured that the medicine is identical to what you had before.

Can medicines have more than one generic name?

No, each medicine has one approved name called the generic name. However, a single generic medicine can be sold under multiple brand names, chosen by different companies that manufacture it. For instance, paracetamol is a generic name, but it's sold under brand names like Panadol® and Calpol®.

How can I tell the difference between a generic and a brand name for a medicine on the packaging?

On medicine packaging, the brand name is usually displayed most prominently and clearly. However, the generic name will always be present somewhere on the packet, often in smaller print. Sometimes, only the generic name appears on the packaging.

What are combination products in medicine?

Combination products are tablets or pills that contain more than one type of medicine. These products are often sold under a single brand name. Despite the brand name, the packaging will list all the individual generic medicines that are combined within that tablet or pill. For example, Solpadol® is a brand name for a combination product containing paracetamol and codeine, which is also generally known as co-codamol.

Are there any medicines that are always prescribed by their brand name?

Yes, some medicines are always prescribed by their specific brand name. This is because there can be significant differences in how much of the medicine ends up in your body (known as bioavailability) between different brands. Examples include certain epilepsy medicines like lamotrigine, theophylline, diltiazem, nifedipine, isosorbide mononitrate, lithium, beclometasone inhalers (e.g., Clenil®, Qvar®), and mesalazine.

Leitura adicional e referências

  • Formulário Nacional Britânico (BNF); Serviços de Evidências NICE (acesso apenas no Reino Unido)
  • Gozzo L, Caraci F, Drago F; Bioequivalence, Drugs with Narrow Therapeutic Index and The Phenomenon of Biocreep: A Critical Analysis of the System for Generic Substitution. Healthcare (Basel). 2022 Jul 26;10(8):1392. doi: 10.3390/healthcare10081392.

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Dr Hayley Willacy, FRCGP

Médico Generalista, Autor Médico

MBChB (1992), DRCOG, DFFP, MRCOG (Part 1) MRCGP (2007), DFSRH (2013), MSc - medical education (2020)

A Dra. Hayley Willacy era uma médica do NHS atuando no noroeste da Inglaterra, que se aposentou da prática clínica em 2022 após 30 anos. 

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Dr Krishna Vakharia, MRCGP

Diretor Médico de Saúde, Optum UK

MBChB, MRCGP(2013), BMedSci (hons), DFSRH, DRCOG, PGDipDerm (Distn)

Dr. Krishna Vakharia é uma médica de clínica geral do NHS. Ela também é examinadora regular do Diploma de Pós-Graduação em Dermatologia Prática na Universidade de Cardiff, além de ser a Diretora Médica de Saúde na Optum UK.

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