MitOxyVit: Mitochondrial network modulation approach using hyperbaric oxygen (HBO) therapy and NNbUVB for treating vitiligo
This research, called MitOxyVit, is exploring new ways to treat vitiligo, a condition where people develop white patches on their skin. The study combines two treatments: hyperbaric oxygen therapy, where you breathe pure oxygen in a special chamber, and NNbUVB, which is a type of light treatment. The main goal is to see how much the white patches improve after 24 weeks of treatment, specifically by measuring how much skin colour returns. Researchers will also look at how effective the treatment is at 12 weeks and monitor if participants experience any side effects. This is a Phase II study, meaning it's an early-stage trial trying to find out if the treatment is promising and safe before larger studies are done.
Em resumo
Sobre o que é este estudo?
This clinical trial is investigating a new approach for treating vitiligo, a condition that causes pale or white patches to appear on the skin. It happens when the cells that produce skin pigment stop working. The study is called MitOxyVit and combines two different treatments: hyperbaric oxygen therapy and a specific type of light treatment called NNbUVB.
Hyperbaric oxygen therapy involves breathing pure oxygen in a pressurised room. This increases the amount of oxygen in your blood and is thought to help repair damaged tissues. The light treatment, NNbUVB, uses a specific wavelength of ultraviolet light, which is already a known treatment for vitiligo, to help stimulate pigment cells. Researchers believe that using these two treatments together might be more effective than using them separately.
The main aim of this study is to see how much the white patches on the skin improve after 24 weeks of treatment. They will use a special scoring system to measure how much colour returns to the skin. They will also check how well the treatment is working after 12 weeks and keep a close eye on any side effects that might occur, ensuring the treatment is safe for patients.
Pontos principais
- This study explores a new combination treatment for vitiligo: oxygen therapy and light treatment.
- It aims to see how much skin colour can be restored over 24 weeks.
- The study also monitors for any side effects to ensure safety.
- It's an early-stage study, meaning researchers are testing if the treatment is promising.
- Participants must be 18 years or older, with no upper age limit.
- Você pode se retirar do estudo a qualquer momento.
Quem pode ser elegível?
To be considered for this study, you need to be an adult, aged 18 years or older. There is no upper age limit, so people of all adult ages can potentially take part. Both men and women are welcome to participate in this research.
While the basic requirements are straightforward, there will be other specific medical conditions or previous treatments that might mean you can't join the study. These are put in place to ensure the safety of participants and the accuracy of the study results.
A doctor involved with the study will carefully go through your medical history and current health to determine if this trial is suitable and safe for you.
Este estudo pode ser adequado para você?
Responda a estas perguntas rápidas para ver se você pode ser elegível. Este é apenas um guia — a decisão final é da equipe de pesquisa.
- Você tem 18 anos ou mais?
- Have you been diagnosed with vitiligo?
- Are you willing and able to attend regular clinic appointments?
- Are you comfortable with the idea of receiving hyperbaric oxygen therapy and light treatment?
O que envolve a participação?
If you decide to take part in this study, you will receive a combination of hyperbaric oxygen therapy and light treatment (NNbUVB). The study will run for a total of 24 weeks, during which you will have regular visits to the clinic.
During these visits, healthcare professionals will assess your skin, usually by measuring the amount of colour that has returned to your vitiligo patches. They will also ask you about how you are feeling and if you have experienced any new symptoms or side effects. Your medical team will explain the exact schedule of treatments and assessments you'll need to attend.
After the initial 24 weeks of treatment, there might be follow-up appointments to see how your skin is doing over a longer period. Everything will be clearly explained to you before you agree to join the study.
Riscos e benefícios potenciais
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Perguntas frequentes
O que é vitiligo?
Vitiligo is a long-term skin condition where patches of skin lose their pigment, causing them to turn white.
What is hyperbaric oxygen therapy?
It's a treatment where you breathe pure oxygen in a special room with higher air pressure than usual. This helps more oxygen get into your body.
What is NNbUVB?
NNbUVB is a type of light treatment using specific ultraviolet light wavelengths, often used to help stimulate pigment production in vitiligo.
How long will the treatment last?
The main treatment period in this study is planned for 24 weeks.
Will I have to pay to participate?
No, you will not have to pay for the treatments or assessments directly related to the study.
Como saber mais
Sempre consulte seu médico ou especialista antes de decidir participar de um estudo.
Discussão
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