Clinical Pre-screening Protocol for Ovarian Cancer

This study is for women who have been diagnosed with a specific type of ovarian cancer called epithelial ovarian cancer. To take part, your cancer must be considered 'platinum-resistant', which means it has grown or returned within six months after you finished a platinum-based chemotherapy. Alternatively, if platinum-based chemotherapy isn't suitable for you, you might also be eligible.

You should have had no more than one previous course of treatment for your platinum-resistant or platinum-ineligible ovarian cancer. Importantly, the doctors will need to be able to get a sample of your original ovarian cancer tissue, or tissue from a tumour that has spread, which was collected during a past procedure like a surgery or biopsy.

However, some people won't be able to join. For example, if your cancer got worse *during* your last platinum-based chemotherapy (this is called 'platinum-refractory'), you won't be eligible. Also, if you have another type of cancer, unless it's a very early stage cancer (stage 1 or 2) that your doctor believes has been cured, you won't be able to participate. Participants must also be 18 years old or older.

If you decide to participate in this study, the main part of it involves providing a small piece of your ovarian cancer tissue. This tissue would have been collected during a past surgery or biopsy and is already stored safely (it's called 'archival' tissue). You won't need to undergo any new procedures just for this study to get the tissue sample. Doctors will then use this sample to perform the special DRP® test.

There are no additional clinic visits, medications to take, or follow-up appointments directly related to this study. The study primarily involves the analysis of your existing tissue sample and medical records related to your past treatments. The total duration of your direct involvement is minimal, as it doesn't require active participation from you beyond the initial consent for your tissue to be used.